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1. Clinical and immunoserological characteristics of anti‐p200 pemphigoid: Comparisons of patients with epitope spreading and non‐epitope spreading NSTL国家科技图书文献中心

Yuan Wang |  Suo Li... -  《International journal of dermatology》 - 2025,64(2) - 359~366 - 共8页

摘要:. Although the phenomenon of epitope spreading has been |  without epitope spreading. Methods We performed a |  combined immunoserological assays. Results Epitope |  non‐epitope spreading group, patients in the epitope |  epitope spreading. Anti‐p200 pemphigoid patients with
关键词: anti‐p200 pemphigoid |  laminin‐γ1 |  p200 |  epitope spreading |  immunoblotting

2. Multi-epitope vaccines Xlc and Ddc against Glaesserella parasuis infection in mice NSTL国家科技图书文献中心

Dai, Lu |  Wan, Jiajia... -  《Veterinary Microbiology》 - 2025,304 - 共10页

摘要:-epitope proteins Xlc and Ddc were obtained by |  %, and 50 %). Overall, the combination of multi-epitope | , and 10. These results indicated that multi-epitope |  study, the B-cell, CTL and Th cell epitopes of CtdB |  concatenating epitopes through linkers. After immunization
关键词: Glaesserella parasuis |  Epitope prediction |  Cross-protection |  Multi-epitope vaccines

3. A computational approach for MHC-restricted multi-epitope vaccine design targeting Oropouche virus structural proteins NSTL国家科技图书文献中心

Silva, Leticia Barbo... |  da Silva, Laura Leon...... -  《Acta tropica.》 - 2025,263 - Article 107575~Article 107575 - 共8页

摘要:-epitope vaccine candidate. RefSeq sequences of the |  Information Virus and submitted to epitope search in Immune |  Epitope Database. Antigenicity, allergenicity, stability |  multi-epitope vaccine candidate, with beta-defensin | -epitope protein with TLR-2, TLR-3, TLR-6, and TLR-8
关键词: Oropouche |  Immunoinformatics |  Vaccinology reverse |  Multi-epitope

4. Designing a novel multi‐epitope antigen for diagnosing human cytomegalovirus infection: An immunoinformatics approach NSTL国家科技图书文献中心

Marzieh Asadi |  Younes Ghasemi... -  《Biotechnology and Applied Biochemistry》 - 2025,72(2) - 469~483 - 共15页

摘要:. Developing multi‐epitope antigens for serological assays | . This study aimed to design a novel multi‐epitope |  appropriate linkers. The designed multi‐epitope antigen |  analysis revealed that the multi‐epitope antigen exhibits |  findings suggest that this multi‐epitope antigen is a
关键词: B‐cell epitope |  diagnosis |  HCMV |  immunoinformatic |  in silico |  multi‐epitope antigen

5. Immunoinformatic approach to design an efficient multi‐epitope peptide vaccine against melanoma NSTL国家科技图书文献中心

Mahvash Dehghankhold |  Navid Nezafat... -  《Biotechnology and Applied Biochemistry》 - 2025,72(1) - 164~186 - 共23页

摘要:. Specifically, the use of epitope melanoma vaccine, a subset | . The aim of this study was to create a multi‐epitope |  factor B (RpfB) adjuvants, and the helper epitope of |  pan HLADR‐binding epitope (PADRE) were incorporated | Abstract Melanoma is known to be the most
关键词: bioinformatics |  melanoma |  molecular dynamics |  multi‐epitope |  vaccine

6. Preparation and epitope identification of a novel monoclonal antibody against 3A protein of Senecavirus A NSTL国家科技图书文献中心

Ling, Xiang-hui |  Zhang, Biao... -  《Veterinary Microbiology》 - 2025,303 - 共11页

摘要: characterize the epitope of mAb 5A7, serial truncated |  assay showed the epitope of mAb 5A7 was |  epitopes are located on the extrinsic membrane domain of | Senecavirus A (SVA) infection causes vesicular |  disease in pigs and acute death of newborn piglets
关键词: Senecavirus A |  3A protein |  Monoclonal antibody |  B cell epitope

7. Design of a multi-epitope vaccine candidate against carrion disease by immunoinformatics approach NSTL国家科技图书文献中心

Rivera-Asencios D. |  Espinoza-Culupu A.... -  《Computers in Biology and Medicine》 - 2025,184 - 109397~109397 - 共12页

摘要:. This study aimed to design a multi-epitope vaccine |  epitopes, as well as CD4+ and CD8+T cell epitopes, were | , Ecuador, Colombia, and worldwide. B-cell epitopes and T | -cell nested epitopes from outer membrane and |  virulence-associated proteins were selected. Epitopes were
关键词: Bartonella bacilliformis |  Carrion's disease |  Immunoinformatics |  Multi-epitope |  TLR4 |  Vaccine

8. Development of polyclonal chicken egg yolk immunoglobulin Y (IgY) antibodies targeting SARS-CoV-2 multi-epitope antigen NSTL国家科技图书文献中心

Fibriani, Azzania |  Naisanu, Katerina... -  《Journal of Virological Methods》 - 2025,331 - 115062~115062 - 共7页

摘要:. After immunizing hens with a SARS-CoV-2 multi-epitope |  to SARS-CoV-2 antigens, both the multi-epitope | Severe acute respiratory syndrome-coronavirus | -2 (SARS-CoV-2) is the primary cause of the |  Coronavirus disease 2019 (COVID-19) pandemic, which affects
关键词: COVID-19 |  SARS-CoV-2 |  Immunodominant epitope |  Multi-epitope |  Polyclonal antibody |  Immunoglobulin Y |  Chicken egg yolk

9. Engineering Base Changes and Epitope-Tagged Alleles in Mice Using Cas9 RNA-Guided Nuclease NSTL国家科技图书文献中心

Marina Gertsenstein |  Lauri G. Lintott... -  《Current Protocols in Mouse Biology》 - 2025,5(4) - Engineering Base/1~Engineering Base/32 - 共32页

摘要:-nucleotide variants to disease states. Epitope tags enable |  for epitope tags—appropriateCas9 protospacer | Mice carrying patient-associated base changes |  are powerful tools to define the causality of single |  immuno-based studies of genes for which no antibodies
关键词: Cas9 |  electroporation |  epitope tags |  genome editing |  microin-jection |  mouse |  single nucleotide variant

10. Designing a T cell multi-epitope vaccine against hRSV with reverse vaccinology: An immunoinformatics approach NSTL国家科技图书文献中心

Guan, Peibin |  Qi, Congyan... -  《Colloids and Surfaces,B.Biointerfaces》 - 2025,251 - 共15页

摘要: epitope vaccine composed of 385 amino acids, consisting |  glycoprotein. The designed multi-epitope vaccine was expected |  epitopes of additional pathogens. | As an infectious viral pathogen, human |  respiratory syncytial virus (hRSV) can cause severe
关键词: Human respiratory syncytial virus (hRSV) |  Multi-epitope vaccine |  Immune simulation |  Immunoinformatics |  Molecular docking
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