NSTL国家科技图书文献中心

1. Amniotic fluid stem cell extracellular vesicles promote lung development via TGF-beta modulation in a fetal rat model of oligohydramnios NSTL国家科技图书文献中心

Doktor, Fabian | Figueira, Rebeca Lop...... - 《Journal of Controlled Release》 - 2025,377 - 427～441 - 共15页

摘要： TGF-beta signaling. Conversely, oligohydramnios | patterning (decreased Sox2 and Sox9 expression), and TGF | -beta* signaling. We then tested antenatal* | -EVs had decreased branching morphogenesis and TGF | -beta* signaling. This is the first study reporting*

关键词： PPROM | Lung development | Stem cell | Exosome | Fetal medicine | Congenital diaphragmatic hernia

2. The impact and mechanisms of YL-IPA08, a potent ligand for the translocator protein (18 kDa) on protection against LPS-induced depression and cognitive dysfunction in rodents NSTL国家科技图书文献中心

Cui, Lin-yu | Duan, Jing-yao ... - 《Metabolic brain disease》 - 2025,40(3) - Article: 137～Article: 137 - 共12页

摘要： anti-inflammatory factors (IL-4, IL-10, TGF-beta* 1* | levels of TGF-beta* 1 and smad3 (member of TGF-beta 1* | pathway) in PFC of LPS mice by TSPO activation. TGF-beta | inflammation regulation and TSPO-TGF-beta* 1/Smad pathway* | inflammatory cytokines (IL-6, IL-1 beta* and TNF-alpha) and*

关键词： Translocator protein (18 kDa) | Depression | Anxiety | Cognitive dysfunction | Transforming growth factor-beta 1 (TGF-beta 1)

3. Transforming growth factor-β in tumor microenvironment: Understanding its impact on monocytes and macrophages for its targeting NSTL国家科技图书文献中心

Hourani, Tetiana | Sharma, Amit ... - 《International reviews of immunology》 - 2025,44(2) - 82～97 - 共16页

摘要： multifaceted role of transforming growth factor beta (TGF | TGF-beta is a pivotal cytokine that | microenvironment (TME). We specifically discuss how TGF-beta | -beta) in cancer biology, focusing on its intricate | current translational and clinical efforts targeting TGF

关键词： Inflammation | macrophages | monocytes | signaling | TGF-beta | tumor microenvironment

4. Integral Roles of the TGFβ Signaling Pathway in Uterine Function and Disease NSTL国家科技图书文献中心

Unser, Anna Catherin... | Monsivais, Diana - 《Endocrinology》 - 2025,166(3) - bqaf032～bqaf032 - 共14页

摘要： transforming growth factor beta (TGF beta) superfamily | the current understanding of how the TGF beta | The uterus is a complex organ that requires | precise signaling networks to mediate functions | necessary for homeostasis and reproductive processes. The

关键词： uterus | endometrium | TGF beta signaling | uterine disease | endometriosis

5. Interactions of flavonoid and coumarin derivative compounds with transforming growth factor-beta receptor 1 (TGF-βR1): integrating virtual screening, molecular dynamics, maximum common substructure, and ADMET approaches in the treatment of idiopathic pulmonary fibrosis NSTL国家科技图书文献中心

Istifli, Erman Salih | Netz, Paulo A. - 《Journal of molecular modeling》 - 2025,31(4) - 共20页

摘要： molecules. Transforming growth factor-beta receptor 1 (TGF | flavonoid and coumarin compounds as novel TGF-beta* R1* | TGF-beta R1 kinase domain (PDB ID: 6B8Y) using | -beta* R1) is a key player in the pathogenesis of IPF* | '-trihydroxyflavone and dicoumarol could be considered novel TGF

关键词： Idiopathic pulmonary fibrosis | Plant-based compounds | Virtual screening | Molecular dynamics | Maximum common substructure | ADMET

6. Induction of SOX17 with stimulation of WNT, TGF-beta, and FGF signaling drives embryonal carcinomas into the yolk-sac tumor lineage resulting in increased cisplatin resistance NSTL国家科技图书文献中心

Kotthoff, Mara | Skowron, Margaretha ...... - 《International Journal of Cancer》 - 2025,156(11) - 2210～2224 - 共15页

摘要： stimulation of WNT, TGF-beta* / Activin, and FGF signaling* | Relapsing germ cell tumor (GCT) patients often | harbor components of the aggressive subtype yolk-sac | tumor (YST), suggesting that YST formation is an | escape mechanism under therapy. Nevertheless, the

关键词： cisplatin resistance | differentiation | embryonal carcinoma | SOX17 / FOXA2 | yolk-sac tumors | yolk‐sac tumors

7. TGFβ2 Promotes the Construction of Fibrotic and Immunosuppressive Tumor Microenvironment in Pancreatic Adenocarcinoma: A Comprehensive Analysis NSTL国家科技图书文献中心

Yu, Xiaofen | Chen, Xuefen ... - 《Molecular biotechnology》 - 2025,67(6) - 2562～2575 - 共14页

摘要： tumor microenvironment (TME). TGF* beta signaling* | , the role of TGF* beta 2 in TME of PAAD remains to be* | elucidated. In this study, we showed that TGF* beta 2 was* | showed that TGF* beta 2 correlated positively with* | showed that TGF* beta 2 correlated with the infiltration*

关键词： TGF beta 2 | Pancreatic adenocarcinoma | Immune infiltrate | Fibroblast | Comprehensive analyses

8. Estrogen Receptor β Activation Mitigates Colitis-associated Intestinal Fibrosis via Inhibition of TGF-β/Smad and TLR4/MyD88/NF-κB Signaling Pathways NSTL国家科技图书文献中心

Ling, Fangmei | Chen, Yidong ... - 《Inflammatory bowel diseases》 - 2025,31(1) - 11～27 - 共17页

摘要： transforming growth factor (TGF)-beta-induced fibroblast | enriched in ECM-receptor interaction, TGF-beta* signaling* | blotting confirmed the involvement of TGF-beta/Smad and | activity of TGF-beta* 1 and TLR4 could be suppressed by ER* | modulation of the TGF-beta/Smad and TLR4/MyD88/NF-kappa B

关键词： intestinal fibrosis | Crohn's disease | estrogen receptor beta | TGF-beta | TLR4

9. Targeting TGF-β: a promising strategy for cancer therapy NSTL国家科技图书文献中心

Himani, Charanjit | Kaur, Charanjit ... - 《Medical oncology.》 - 2025,42(5) - Article: 142～Article: 142 - 共22页

摘要：Transforming growth factor beta (TGF-beta) has | promoter in different stages of cancer. TGF-beta* emerged* | are focusing on the different types of TGF- beta | , colorectal cancer, lung cancer and ovarian cancer. TGF-beta | receptor kinase inhibitors. In recent studies, TGF- beta

关键词： TGF-beta inhibitors | Anticancer | Anti-breast cancer | Skin cancer | Colorectal cancer

10. Shh Protects the Injured Spinal Cord in Mice by Promoting the Proliferation and Inhibiting the Apoptosis of Nerve Cells via the Gli1-TGF-β1/ERK Axis NSTL国家科技图书文献中心

Liu, Yunfei | Hou, Meihua ... - 《Cell biochemistry and function》 - 2025,43(1) - e70038～e70038 - 共17页

摘要： growth factor-beta (TGF-beta) signaling pathway | , inhibiting the classic TGF-beta* 1/Smad signaling pathway* | and activating the TGF-beta* 1/extracellular* | research indicates that Gli1 regulates the transforming | Spinal cord injury (SCI) is a common

摘要： TGF-beta signaling. Conversely, oligohydramnios | patterning (decreased Sox2 and Sox9 expression), and TGF | -beta* signaling. We then tested antenatal* | -EVs had decreased branching morphogenesis and TGF | -beta* signaling. This is the first study reporting*

关键词： PPROM | Lung development | Stem cell | Exosome | Fetal medicine | Congenital diaphragmatic hernia

关键词： Translocator protein (18 kDa) | Depression | Anxiety | Cognitive dysfunction | Transforming growth factor-beta 1 (TGF-beta 1)

摘要： multifaceted role of transforming growth factor beta (TGF | TGF-beta is a pivotal cytokine that | microenvironment (TME). We specifically discuss how TGF-beta | -beta) in cancer biology, focusing on its intricate | current translational and clinical efforts targeting TGF

关键词： Inflammation | macrophages | monocytes | signaling | TGF-beta | tumor microenvironment

摘要： transforming growth factor beta (TGF beta) superfamily | the current understanding of how the TGF beta | The uterus is a complex organ that requires | precise signaling networks to mediate functions | necessary for homeostasis and reproductive processes. The

关键词： uterus | endometrium | TGF beta signaling | uterine disease | endometriosis

摘要： molecules. Transforming growth factor-beta receptor 1 (TGF | flavonoid and coumarin compounds as novel TGF-beta* R1* | TGF-beta R1 kinase domain (PDB ID: 6B8Y) using | -beta* R1) is a key player in the pathogenesis of IPF* | '-trihydroxyflavone and dicoumarol could be considered novel TGF

关键词： Idiopathic pulmonary fibrosis | Plant-based compounds | Virtual screening | Molecular dynamics | Maximum common substructure | ADMET

摘要： stimulation of WNT, TGF-beta* / Activin, and FGF signaling* | Relapsing germ cell tumor (GCT) patients often | harbor components of the aggressive subtype yolk-sac | tumor (YST), suggesting that YST formation is an | escape mechanism under therapy. Nevertheless, the

关键词： cisplatin resistance | differentiation | embryonal carcinoma | SOX17 / FOXA2 | yolk-sac tumors | yolk‐sac tumors

摘要： tumor microenvironment (TME). TGF* beta signaling* | , the role of TGF* beta 2 in TME of PAAD remains to be* | elucidated. In this study, we showed that TGF* beta 2 was* | showed that TGF* beta 2 correlated positively with* | showed that TGF* beta 2 correlated with the infiltration*

关键词： TGF beta 2 | Pancreatic adenocarcinoma | Immune infiltrate | Fibroblast | Comprehensive analyses

关键词： intestinal fibrosis | Crohn's disease | estrogen receptor beta | TGF-beta | TLR4

摘要：Transforming growth factor beta (TGF-beta) has | promoter in different stages of cancer. TGF-beta* emerged* | are focusing on the different types of TGF- beta | , colorectal cancer, lung cancer and ovarian cancer. TGF-beta | receptor kinase inhibitors. In recent studies, TGF- beta

关键词： TGF-beta inhibitors | Anticancer | Anti-breast cancer | Skin cancer | Colorectal cancer

摘要： growth factor-beta (TGF-beta) signaling pathway | , inhibiting the classic TGF-beta* 1/Smad signaling pathway* | and activating the TGF-beta* 1/extracellular* | research indicates that Gli1 regulates the transforming | Spinal cord injury (SCI) is a common

关键词： ERK | Gli1 | Shh | spinal cord injury | TGF-beta 1

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： TGF-beta signaling. Conversely, oligohydramnios | patterning (decreased Sox2 and Sox9 expression), and TGF | -beta signaling. We then tested antenatal | -EVs had decreased branching morphogenesis and TGF | -beta signaling. This is the first study reporting

关键词： PPROM | Lung development | Stem cell | Exosome | Fetal medicine | Congenital diaphragmatic hernia

摘要： anti-inflammatory factors (IL-4, IL-10, TGF-beta 1 | levels of TGF-beta 1 and smad3 (member of TGF-beta 1 | pathway) in PFC of LPS mice by TSPO activation. TGF-beta | inflammation regulation and TSPO-TGF-beta 1/Smad pathway | inflammatory cytokines (IL-6, IL-1 beta and TNF-alpha) and

关键词： Translocator protein (18 kDa) | Depression | Anxiety | Cognitive dysfunction | Transforming growth factor-beta 1 (TGF-beta 1)

摘要： multifaceted role of transforming growth factor beta (TGF | TGF-beta is a pivotal cytokine that | microenvironment (TME). We specifically discuss how TGF-beta | -beta) in cancer biology, focusing on its intricate | current translational and clinical efforts targeting TGF

关键词： Inflammation | macrophages | monocytes | signaling | TGF-beta | tumor microenvironment

摘要： transforming growth factor beta (TGF beta) superfamily | the current understanding of how the TGF beta | The uterus is a complex organ that requires | precise signaling networks to mediate functions | necessary for homeostasis and reproductive processes. The

关键词： uterus | endometrium | TGF beta signaling | uterine disease | endometriosis

摘要： molecules. Transforming growth factor-beta receptor 1 (TGF | flavonoid and coumarin compounds as novel TGF-beta R1 | TGF-beta R1 kinase domain (PDB ID: 6B8Y) using | -beta R1) is a key player in the pathogenesis of IPF | '-trihydroxyflavone and dicoumarol could be considered novel TGF

关键词： Idiopathic pulmonary fibrosis | Plant-based compounds | Virtual screening | Molecular dynamics | Maximum common substructure | ADMET

摘要： stimulation of WNT, TGF-beta / Activin, and FGF signaling | Relapsing germ cell tumor (GCT) patients often | harbor components of the aggressive subtype yolk-sac | tumor (YST), suggesting that YST formation is an | escape mechanism under therapy. Nevertheless, the

关键词： cisplatin resistance | differentiation | embryonal carcinoma | SOX17 / FOXA2 | yolk-sac tumors | yolk‐sac tumors

摘要： tumor microenvironment (TME). TGF beta signaling | , the role of TGF beta 2 in TME of PAAD remains to be | elucidated. In this study, we showed that TGF beta 2 was | showed that TGF beta 2 correlated positively with | showed that TGF beta 2 correlated with the infiltration

关键词： TGF beta 2 | Pancreatic adenocarcinoma | Immune infiltrate | Fibroblast | Comprehensive analyses

关键词： intestinal fibrosis | Crohn's disease | estrogen receptor beta | TGF-beta | TLR4

摘要：Transforming growth factor beta (TGF-beta) has | promoter in different stages of cancer. TGF-beta emerged | are focusing on the different types of TGF- beta | , colorectal cancer, lung cancer and ovarian cancer. TGF-beta | receptor kinase inhibitors. In recent studies, TGF- beta

关键词： TGF-beta inhibitors | Anticancer | Anti-breast cancer | Skin cancer | Colorectal cancer

摘要： growth factor-beta (TGF-beta) signaling pathway | , inhibiting the classic TGF-beta 1/Smad signaling pathway | and activating the TGF-beta 1/extracellular | research indicates that Gli1 regulates the transforming | Spinal cord injury (SCI) is a common

关键词： ERK | Gli1 | Shh | spinal cord injury | TGF-beta 1

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： TGF-beta signaling. Conversely, oligohydramnios | patterning (decreased Sox2 and Sox9 expression), and TGF | -beta* signaling. We then tested antenatal* | -EVs had decreased branching morphogenesis and TGF | -beta* signaling. This is the first study reporting*

摘要： molecules. Transforming growth factor-beta receptor 1 (TGF | flavonoid and coumarin compounds as novel TGF-beta* R1* | TGF-beta R1 kinase domain (PDB ID: 6B8Y) using | -beta* R1) is a key player in the pathogenesis of IPF* | '-trihydroxyflavone and dicoumarol could be considered novel TGF

摘要： stimulation of WNT, TGF-beta* / Activin, and FGF signaling* | Relapsing germ cell tumor (GCT) patients often | harbor components of the aggressive subtype yolk-sac | tumor (YST), suggesting that YST formation is an | escape mechanism under therapy. Nevertheless, the

摘要： tumor microenvironment (TME). TGF* beta signaling* | , the role of TGF* beta 2 in TME of PAAD remains to be* | elucidated. In this study, we showed that TGF* beta 2 was* | showed that TGF* beta 2 correlated positively with* | showed that TGF* beta 2 correlated with the infiltration*

摘要：Transforming growth factor beta (TGF-beta) has | promoter in different stages of cancer. TGF-beta* emerged* | are focusing on the different types of TGF- beta | , colorectal cancer, lung cancer and ovarian cancer. TGF-beta | receptor kinase inhibitors. In recent studies, TGF- beta

摘要： growth factor-beta (TGF-beta) signaling pathway | , inhibiting the classic TGF-beta* 1/Smad signaling pathway* | and activating the TGF-beta* 1/extracellular* | research indicates that Gli1 regulates the transforming | Spinal cord injury (SCI) is a common