NSTL国家科技图书文献中心

1. Intracellular Magnetic Hyperthermia Enables Concurrent Down-Regulation of CD47 and SIRPα To Potentiate Antitumor Immunity NSTL国家科技图书文献中心

Wang, Siyao | Jiao, Wangbo ... - 《Nano letters》 - 2024,24(9) - 2894～2903 - 共10页

摘要： avenues for cancer therapy. Targeting phagocytosis | checkpoints, particularly the CD47-signal regulatory protein | Harnessing the potential of tumor-associated | macrophages (TAMs) to engulf tumor cells offers promising | alpha (SIRP alpha) axis, is crucial for modulating TAM

关键词： Magnetic hyperthermia | ferrimagnetic vortex-domainironoxide nanoring | CD47-SIRP alpha axis inhibition | enhanced macrophage phagocytosis | hepatocellular carcinomaimmunotherapy | CANCER | MACROPHAGES | NANORINGS | ESCAPE | TARGET

2. Siglec10 Expression on Tumor-associated Macrophages Is an Independent Prognostic Factor in Stage I Lung Adenocarcinoma NSTL国家科技图书文献中心

CHIHIRO YOSHIDA | KYUICHI KADOTA ... - 《Anticancer Research: International Journal of Cancer Research and Treatment》 - 2024,44(3) - 1289～1297 - 共9页

摘要： phagocytic checkpoints* in lung adenocarcinoma remains* | and prognostic significance of phagocytosis | checkpoints mediated by Siglec10 in TAMs of patients with | Background/aim: Prognostic indicators for | postoperative lung adenocarcinoma are elusive. The interaction

关键词： CD24 | Siglec10 | immune evasion | lung adenocarcinoma | prognostic factor.

3. Multi-omics analysis reveals GAPDH posttranscriptional regulation of IFN-γ and PHGDH as a metabolic checkpoint of microglia polarization NSTL国家科技图书文献中心

Yang, Shangchen | Yuan, Ziqi ... - 《Brain, Behavior, and Immunity》 - 2024,117 - 155～166 - 共12页

摘要： microglia functions, including phagocytosis* and cytokine* | mechanism of metabolic checkpoints* in human microglia or* | A "switch" in the metabolic pattern of | microglia is considered to be required to meet the | metabolic demands of cell survival and functions. However

关键词： Metabolic checkpoint | Microglia | GAPDH | PHGDH | IFN-gamma | Polarization

4. Understanding the regulation of "Don't Eat-Me" signals by inflammatory signaling pathways in the tumor microenvironment for more effective therapy NSTL国家科技图书文献中心

Karizak, Ashkan Zare | Salmasi, Zahra ... - 《Journal of Cancer Research and Clinical Oncology》 - 2023,149(1) - 511～529 - 共19页

摘要： checkpoints are inhibitors that regulate immunity as vital | . Moreover, the immune checkpoints* are involved in* | checkpoints as a signal from "self" and their expression on | healthy cells prevent phagocytosis. Cells (e.g | checkpoints, such as low CD47 and/or PD-L1, are phagocytosed

关键词： CD47-SIRP alpha pathway | Combinational cancer immunotherapy | Precision medicine | Therapeutic resistance | Phagocytosis checkpoints | PD-L1 | ACUTE MYELOID-LEUKEMIA | SIRP-ALPHA | CD47 | CELL...

5. Targeting phagocytosis to enhance antitumor immunity NSTL国家科技图书文献中心

Huntoon, Kristin | Lee, DaeYong ... - 《Trends in cancer.》 - 2023,9(8) - 650～665 - 共16页

摘要： phagocytosis checkpoints on the activation of antitumor | immunotherapy that targets adaptive immune checkpoints | . However, innate immune checkpoints, which can hinder the | surveillance processes, such as phagocytosis, and incorporate | Many patients with metastatic or treatment

关键词： TUMOR-ASSOCIATED MACROPHAGES | CD47 BLOCKADE | INHIBITS PHAGOCYTOSIS | MEDIATED DESTRUCTION | INDUCIBLE EXPRESSION | THERAPEUTIC TARGET | APOPTOTIC CELLS | STEM-CELLS | CLASS-I | CANCER

6. The Impact of Colistin Resistance on the Activation of Innate Immunity by Lipopolysaccharide Modification NSTL国家科技图书文献中心

Avendano-Ortiz, Jose | Ponce-Alonso, Manuel ... - 《Infection and immunity.》 - 2023,91(2) - e00012-23～e00012-23 - 共11页

摘要： determine their survival after phagocytosis* and induction* | after phagocytosis* and elicits a higher inflammatory* | Colistin resistance is acquired by different | lipopolysaccharide (LPS) modifications. We proposed to evaluate the | of effect in vivo colistin resistance acquisition

关键词： colistin | antibiotic resistance | LPS modification | monocytes | phagocytosis | inflammation | immune checkpoints | CHECKPOINT BLOCKADE | CYSTIC-FIBROSIS | LPS

7. The new progress in cancer immunotherapy NSTL国家科技图书文献中心

Shimu, Ajmeri Sultan... | Wei, Hua-xing ... - 《Clinical and experimental medicine》 - 2023,23(3) - 553～567 - 共15页

摘要： innate and adaptive immune checkpoints* which play a* | , as well as other intrinsic and phagocytosis | checkpoints. Together, these insights will pave the way for | The cross talk between immune and non-immune | cells in the tumor microenvironment leads to

关键词： Cancer | Immunotherapy | Immune checkpoint | Siglec | SIRP-alpha | NK cells | TUMOR-ASSOCIATED MACROPHAGES | INNATE IMMUNE-RESPONSE | REGULATORY T-CELLS | ACQUIRED-RESISTANCE...

8. PD-L1 antibody enhanced beta-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model NSTL国家科技图书文献中心

Hu, Xin | Shui, Yifang ... - 《Cancer immunology, immunotherapy :》 - 2023,72(3) - 719～731 - 共13页

摘要： inhibit macrophage phagocytosis* and PD-L1 could induce a* | CD11b(+) cell immune checkpoints* in the melanoma model.* | In the tumor microenvironment (TME), one of | the major functions of tumor-recruited CD11b | (+) cells are the suppression of the T-cell-mediated anti

关键词： Tumor-recruited CD11b(+) cells | beta-glucan | PD-L1 | Tumor-infiltrating lymphocytes | Tumor microenvironment | INFILTRATING MYELOID CELLS | T-CELLS | TUMOR-GROWTH | DRUG | COMBINATION...

9. IL2RA+VSIG4+ tumor-associated macrophage is a key subpopulation of the immunosuppressive microenvironment in anaplastic thyroid cancer NSTL国家科技图书文献中心

Pan Z. | Bao L.... - 《Biochimica et biophysica acta. Molecular basis of disease: BBA》 - 2023,1869(1) - 166591～166591 - 共7页

摘要： oxidative phosphorylation (M2 phenotype) and phagocytosis | + T cells and Tregs through immune checkpoints* (such* | ? 2022Extensive infiltration of tumor | -associated macrophages was correlated poor prognosis in | anaplastic thyroid cancer (ATC). However, the heterogeneity

关键词： Anaplastic thyroid cancer | Heterogeneity | Immune escape | Macrophage | Single-cell RNA-sequencing

10. Targeting macrophage-mediated tumor cell phagocytosis: An overview of phagocytosis checkpoints blockade, nanomedicine intervention, and engineered CAR-macrophage therapy NSTL国家科技图书文献中心

Moradinasab S. | Pourbagheri-Sigarood...... - 《International immunopharmacology》 - 2022,103 - 108499～108499 - 共7页

摘要： of macrophage phagocytosis* and consequent adaptive* | clinical data, targeting macrophage phagocytosis* has* | macrophage phagocytosis, such as blocking phagocytosis | checkpoints and exploiting nanoparticles as efficient | approaches in elevating macrophages-mediated phagocytosis

摘要： avenues for cancer therapy. Targeting phagocytosis | checkpoints, particularly the CD47-signal regulatory protein | Harnessing the potential of tumor-associated | macrophages (TAMs) to engulf tumor cells offers promising | alpha (SIRP alpha) axis, is crucial for modulating TAM

关键词： Magnetic hyperthermia | ferrimagnetic vortex-domainironoxide nanoring | CD47-SIRP alpha axis inhibition | enhanced macrophage phagocytosis | hepatocellular carcinomaimmunotherapy | CANCER | MACROPHAGES | NANORINGS | ESCAPE | TARGET

摘要： phagocytic checkpoints* in lung adenocarcinoma remains* | and prognostic significance of phagocytosis | checkpoints mediated by Siglec10 in TAMs of patients with | Background/aim: Prognostic indicators for | postoperative lung adenocarcinoma are elusive. The interaction

关键词： CD24 | Siglec10 | immune evasion | lung adenocarcinoma | prognostic factor.

摘要： microglia functions, including phagocytosis* and cytokine* | mechanism of metabolic checkpoints* in human microglia or* | A "switch" in the metabolic pattern of | microglia is considered to be required to meet the | metabolic demands of cell survival and functions. However

关键词： Metabolic checkpoint | Microglia | GAPDH | PHGDH | IFN-gamma | Polarization

摘要： checkpoints are inhibitors that regulate immunity as vital | . Moreover, the immune checkpoints* are involved in* | checkpoints as a signal from "self" and their expression on | healthy cells prevent phagocytosis. Cells (e.g | checkpoints, such as low CD47 and/or PD-L1, are phagocytosed

关键词： CD47-SIRP alpha pathway | Combinational cancer immunotherapy | Precision medicine | Therapeutic resistance | Phagocytosis checkpoints | PD-L1 | ACUTE MYELOID-LEUKEMIA | SIRP-ALPHA | CD47 | CELL...

摘要： phagocytosis checkpoints on the activation of antitumor | immunotherapy that targets adaptive immune checkpoints | . However, innate immune checkpoints, which can hinder the | surveillance processes, such as phagocytosis, and incorporate | Many patients with metastatic or treatment

关键词： TUMOR-ASSOCIATED MACROPHAGES | CD47 BLOCKADE | INHIBITS PHAGOCYTOSIS | MEDIATED DESTRUCTION | INDUCIBLE EXPRESSION | THERAPEUTIC TARGET | APOPTOTIC CELLS | STEM-CELLS | CLASS-I | CANCER

摘要： determine their survival after phagocytosis* and induction* | after phagocytosis* and elicits a higher inflammatory* | Colistin resistance is acquired by different | lipopolysaccharide (LPS) modifications. We proposed to evaluate the | of effect in vivo colistin resistance acquisition

关键词： colistin | antibiotic resistance | LPS modification | monocytes | phagocytosis | inflammation | immune checkpoints | CHECKPOINT BLOCKADE | CYSTIC-FIBROSIS | LPS

摘要： innate and adaptive immune checkpoints* which play a* | , as well as other intrinsic and phagocytosis | checkpoints. Together, these insights will pave the way for | The cross talk between immune and non-immune | cells in the tumor microenvironment leads to

关键词： Cancer | Immunotherapy | Immune checkpoint | Siglec | SIRP-alpha | NK cells | TUMOR-ASSOCIATED MACROPHAGES | INNATE IMMUNE-RESPONSE | REGULATORY T-CELLS | ACQUIRED-RESISTANCE...

摘要： inhibit macrophage phagocytosis* and PD-L1 could induce a* | CD11b(+) cell immune checkpoints* in the melanoma model.* | In the tumor microenvironment (TME), one of | the major functions of tumor-recruited CD11b | (+) cells are the suppression of the T-cell-mediated anti

关键词： Tumor-recruited CD11b(+) cells | beta-glucan | PD-L1 | Tumor-infiltrating lymphocytes | Tumor microenvironment | INFILTRATING MYELOID CELLS | T-CELLS | TUMOR-GROWTH | DRUG | COMBINATION...

摘要： oxidative phosphorylation (M2 phenotype) and phagocytosis | + T cells and Tregs through immune checkpoints* (such* | ? 2022Extensive infiltration of tumor | -associated macrophages was correlated poor prognosis in | anaplastic thyroid cancer (ATC). However, the heterogeneity

关键词： Anaplastic thyroid cancer | Heterogeneity | Immune escape | Macrophage | Single-cell RNA-sequencing

摘要： of macrophage phagocytosis* and consequent adaptive* | clinical data, targeting macrophage phagocytosis* has* | macrophage phagocytosis, such as blocking phagocytosis | checkpoints and exploiting nanoparticles as efficient | approaches in elevating macrophages-mediated phagocytosis

关键词： CAR-macrophage | Immunotherapy | Nanomedicine | Phagocytosis Checkpoints Blockade | Tumor-associated Macrophage

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： avenues for cancer therapy. Targeting phagocytosis | checkpoints, particularly the CD47-signal regulatory protein | Harnessing the potential of tumor-associated | macrophages (TAMs) to engulf tumor cells offers promising | alpha (SIRP alpha) axis, is crucial for modulating TAM

关键词： Magnetic hyperthermia | ferrimagnetic vortex-domainironoxide nanoring | CD47-SIRP alpha axis inhibition | enhanced macrophage phagocytosis | hepatocellular carcinomaimmunotherapy | CANCER | MACROPHAGES | NANORINGS | ESCAPE | TARGET

摘要： phagocytic checkpoints in lung adenocarcinoma remains | and prognostic significance of phagocytosis | checkpoints mediated by Siglec10 in TAMs of patients with | Background/aim: Prognostic indicators for | postoperative lung adenocarcinoma are elusive. The interaction

关键词： CD24 | Siglec10 | immune evasion | lung adenocarcinoma | prognostic factor.

摘要： microglia functions, including phagocytosis and cytokine | mechanism of metabolic checkpoints in human microglia or | A "switch" in the metabolic pattern of | microglia is considered to be required to meet the | metabolic demands of cell survival and functions. However

关键词： Metabolic checkpoint | Microglia | GAPDH | PHGDH | IFN-gamma | Polarization

摘要： checkpoints are inhibitors that regulate immunity as vital | . Moreover, the immune checkpoints are involved in | checkpoints as a signal from "self" and their expression on | healthy cells prevent phagocytosis. Cells (e.g | checkpoints, such as low CD47 and/or PD-L1, are phagocytosed

关键词： CD47-SIRP alpha pathway | Combinational cancer immunotherapy | Precision medicine | Therapeutic resistance | Phagocytosis checkpoints | PD-L1 | ACUTE MYELOID-LEUKEMIA | SIRP-ALPHA | CD47 | CELL...

摘要： phagocytosis checkpoints on the activation of antitumor | immunotherapy that targets adaptive immune checkpoints | . However, innate immune checkpoints, which can hinder the | surveillance processes, such as phagocytosis, and incorporate | Many patients with metastatic or treatment

关键词： TUMOR-ASSOCIATED MACROPHAGES | CD47 BLOCKADE | INHIBITS PHAGOCYTOSIS | MEDIATED DESTRUCTION | INDUCIBLE EXPRESSION | THERAPEUTIC TARGET | APOPTOTIC CELLS | STEM-CELLS | CLASS-I | CANCER

摘要： determine their survival after phagocytosis and induction | after phagocytosis and elicits a higher inflammatory | Colistin resistance is acquired by different | lipopolysaccharide (LPS) modifications. We proposed to evaluate the | of effect in vivo colistin resistance acquisition

关键词： colistin | antibiotic resistance | LPS modification | monocytes | phagocytosis | inflammation | immune checkpoints | CHECKPOINT BLOCKADE | CYSTIC-FIBROSIS | LPS

摘要： innate and adaptive immune checkpoints which play a | , as well as other intrinsic and phagocytosis | checkpoints. Together, these insights will pave the way for | The cross talk between immune and non-immune | cells in the tumor microenvironment leads to

关键词： Cancer | Immunotherapy | Immune checkpoint | Siglec | SIRP-alpha | NK cells | TUMOR-ASSOCIATED MACROPHAGES | INNATE IMMUNE-RESPONSE | REGULATORY T-CELLS | ACQUIRED-RESISTANCE...

摘要： inhibit macrophage phagocytosis and PD-L1 could induce a | CD11b(+) cell immune checkpoints in the melanoma model. | In the tumor microenvironment (TME), one of | the major functions of tumor-recruited CD11b | (+) cells are the suppression of the T-cell-mediated anti

关键词： Tumor-recruited CD11b(+) cells | beta-glucan | PD-L1 | Tumor-infiltrating lymphocytes | Tumor microenvironment | INFILTRATING MYELOID CELLS | T-CELLS | TUMOR-GROWTH | DRUG | COMBINATION...

摘要： oxidative phosphorylation (M2 phenotype) and phagocytosis | + T cells and Tregs through immune checkpoints (such | ? 2022Extensive infiltration of tumor | -associated macrophages was correlated poor prognosis in | anaplastic thyroid cancer (ATC). However, the heterogeneity

关键词： Anaplastic thyroid cancer | Heterogeneity | Immune escape | Macrophage | Single-cell RNA-sequencing

摘要： of macrophage phagocytosis and consequent adaptive | clinical data, targeting macrophage phagocytosis has | macrophage phagocytosis, such as blocking phagocytosis | checkpoints and exploiting nanoparticles as efficient | approaches in elevating macrophages-mediated phagocytosis

关键词： CAR-macrophage | Immunotherapy | Nanomedicine | Phagocytosis Checkpoints Blockade | Tumor-associated Macrophage

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： phagocytic checkpoints* in lung adenocarcinoma remains* | and prognostic significance of phagocytosis | checkpoints mediated by Siglec10 in TAMs of patients with | Background/aim: Prognostic indicators for | postoperative lung adenocarcinoma are elusive. The interaction

摘要： microglia functions, including phagocytosis* and cytokine* | mechanism of metabolic checkpoints* in human microglia or* | A "switch" in the metabolic pattern of | microglia is considered to be required to meet the | metabolic demands of cell survival and functions. However

摘要： checkpoints are inhibitors that regulate immunity as vital | . Moreover, the immune checkpoints* are involved in* | checkpoints as a signal from "self" and their expression on | healthy cells prevent phagocytosis. Cells (e.g | checkpoints, such as low CD47 and/or PD-L1, are phagocytosed

摘要： determine their survival after phagocytosis* and induction* | after phagocytosis* and elicits a higher inflammatory* | Colistin resistance is acquired by different | lipopolysaccharide (LPS) modifications. We proposed to evaluate the | of effect in vivo colistin resistance acquisition

摘要： innate and adaptive immune checkpoints* which play a* | , as well as other intrinsic and phagocytosis | checkpoints. Together, these insights will pave the way for | The cross talk between immune and non-immune | cells in the tumor microenvironment leads to

摘要： inhibit macrophage phagocytosis* and PD-L1 could induce a* | CD11b(+) cell immune checkpoints* in the melanoma model.* | In the tumor microenvironment (TME), one of | the major functions of tumor-recruited CD11b | (+) cells are the suppression of the T-cell-mediated anti

摘要： oxidative phosphorylation (M2 phenotype) and phagocytosis | + T cells and Tregs through immune checkpoints* (such* | ? 2022Extensive infiltration of tumor | -associated macrophages was correlated poor prognosis in | anaplastic thyroid cancer (ATC). However, the heterogeneity

摘要： of macrophage phagocytosis* and consequent adaptive* | clinical data, targeting macrophage phagocytosis* has* | macrophage phagocytosis, such as blocking phagocytosis | checkpoints and exploiting nanoparticles as efficient | approaches in elevating macrophages-mediated phagocytosis