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1. Modulating the phosphorylation status of target proteins through bifunctional molecules NSTL国家科技图书文献中心

He, Qindi |  Wang, Zhijie... -  《Drug discovery today》 - 2025,30(2) - Article 104307~Article 104307 - 共15页

摘要:Phosphorylation is an important form of | . Dysregulation of phosphorylation is closely associated with |  phosphorylation status of POIs by phosphorylation-regulating |  kinases/phosphatases, and thus alter the phosphorylation |  protein post- translational modification (PTM) in cells
关键词: phosphorylation |  dephosphorylation |  bifunctional molecules |  chemically induced proximity |  post-translational modification

2. Visible-light-promoted phosphorylation carbonylation of unactivated alkenes NSTL国家科技图书文献中心

Miao, Ren-Guan |  Wang, Yuanrui... -  《Journal of Catalysis》 - 2025,442 - 共5页

摘要: presented a visible light-promoted phosphorylation | Phosphorus-containing compounds represent a |  class of chemicals of great significance. Therefore | , it is of high value to develop efficient C-P bond |  formation methods. However, the activity of phosphoryl
关键词: Carbonylation |  Photocatalyst |  Alkene |  Phosphorylation |  4-diketone |  Double functionalization

3. DeepPhoPred: Accurate Deep Learning Model to Predict Microbial Phosphorylation NSTL国家科技图书文献中心

Ahmed, Faisal |  Sharma, Alok... -  《Proteins》 - 2025,93(2) - 465~481 - 共17页

摘要:Phosphorylation is a substantial | . Phosphorylation prediction in a microbial organism can assist in |  phosphorylation sites are costly, slow, and tedious. Hence low |  information to predict phosphorylation sites. Our empirical |  outperforms the existing microbial phosphorylation site
关键词: classification |  convolutional neural network |  evolutionary information |  imbalance learning |  microbial phosphorylation |  posttranslational modification |  structural information

4. Asymptotic expansions beyond the tQSSA for the double phosphorylation mechanism NSTL国家科技图书文献中心

Alberto M. Bersani |  Alessandro Borri... -  《Mathematics and computers in simulation》 - 2025,233(Jul.) - 137~164 - 共28页

摘要: phosphorylation (dephosphorylation) enzymatic reaction, or | In this paper we study the asymptotic |  properties of the mathematical model of the double |  futile cycle. Starting from the total quasi-steady |  state approximation (tQSSA), and applying singular
关键词: Double phosphorylation |  Michaelis-Menten kinetics |  Singular perturbations |  Asymptotic expansions |  Total quasi-steady state approximation |  Center manifold

5. CERK1-mediated phosphorylation of PBL19 is crucial for antifungal defense in plants NSTL国家科技图书文献中心

Li, Yujia |  Huang, Xiangjuan... -  《Planta》 - 2025,261(3) - 共8页

摘要: against pathogens. Protein phosphorylation plays a | , PBL19 undergoes phosphorylation-mediated by the |  identified eight specific phosphorylation sites on PBL19 |  phosphorylation-mediated signaling to combat fungal pathogens | Main conclusionPhosphorylation of PBL19
关键词: Chitin |  PBL19 |  CERK1 |  Phosphorylation |  Fungal resistance

6. Protein phosphatase PP2C19 controls hypocotyl phototropism through the phosphorylation modification of NONPHOTOTROPIC HYPOCOTYL3 in Arabidopsis NSTL国家科技图书文献中心

Sakai, Tatsuya |  Haga, Ken... -  《Plant and cell physiology》 - 2025,66(1) - 23~35 - 共13页

摘要: but also by the phosphorylation status of the |  and a BL form of the phosphorylation modification |  reverse reaction of NPH3 phosphorylation modification |  reaction of NPH3 phosphorylation, which acts as a phot1 | Plants exhibit shoot growth in the direction
关键词: Arabidopsis |  phototropism |  PP2C |  NPH3 |  phosphorylation

7. Isoliquiritigenin attenuates tumor progression and PD-L1 expression by inhibiting the phosphorylation of STAT3 in melanoma NSTL国家科技图书文献中心

Zeng, Haiyan |  Guo, Aoxiang... -  《Medical oncology.》 - 2025,42(4) - Article: 118~Article: 118 - 共10页

摘要: phosphorylation. TIMER algorithm analysis showed that the levels |  phosphorylation inhibitor Stattic could enhance the effect of |  expression by repressing the phosphorylation of STAT3 | Isoliquiritigenin (ISL) has been reported with |  antitumor activities. While, the underlying molecular
关键词: Isoliquiritigenin |  STAT3 phosphorylation |  PD-L1 |  Melanoma

8. Phosphorylation of ADF7-Mediated by AGC1.7 Regulates Pollen Germination in Arabidopsis thaliana NSTL国家科技图书文献中心

Li, Xiaoyi |  Yu, Qin... -  《Plant, Cell & Environment》 - 2025,48(2) - 1149~1161 - 共13页

摘要: phosphorylation to regulate the dynamics of the actin filaments | . Expression of the phosphorylation-mimetic mutant protein |  model whereby AGC1.7-mediated ADF7 phosphorylation |  with ADF7 in vitro and in vivo. AGC1.7 phosphorylates | Actin depolymerizing factors (ADFs), like
关键词: actin depolymerization factors |  ADF7 |  AGC1.7 |  phosphorylation |  pollen germination

9. Phosphorylation of PA at serine 225 enhances viral fitness of the highly pathogenic H5N1 avian influenza virus in mice NSTL国家科技图书文献中心

Zhang, Manyu |  Zeng, Zixiong... -  《Veterinary Microbiology》 - 2025,302 - 共16页

摘要: how phosphorylation regulates this protein and |  identified PA S225 as the phosphorylation site in the |  investigated the role of phosphorylation in regulating PA |  S225A) or continuous phosphorylation (PA S225E |  assay in vitro showed that PA S225A phosphorylation
关键词: PA |  Phosphorylation |  S225 |  Virulence |  Mice

10. A confined-water-assisted mechanochemical approach for solvent-free surface phosphorylation of cellulose NSTL国家科技图书文献中心

Kuang, Yanhao |  Wang, Wenyan... -  《Cellulose》 - 2025,32(3) - 1527~1538 - 共12页

摘要:-confined reaction to facilitate cellulose phosphorylation |  the phosphorylation process. As a result, the |  mechanochemical phosphorylation of cellulose, and can also be |  phosphorylating agents on the cellulose surface, facilitating |  phosphorylated cellulose demonstrated a high degree of
关键词: Cellulose |  Mechanochemistry |  Hydration layer |  Surface-confined reaction |  Phosphorylation
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