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1. Spatial Transcriptomics of the Respiratory System NSTL国家科技图书文献中心

Megas, Stathis |  Wilbrey-Clark, Anna... -  《Annual Review of Physiology》 - 2025,87 - 447~470 - 共24页

摘要: commonly used spatial analysis workflows, highlighting |  that will augment how we interpret spatial data |  spatially resolved transcriptomics is already providing | Over the last decade, single-cell genomics has |  revealed remarkable heterogeneity and plasticity of cell
关键词: respiratory system |  lung |  spatial transcriptomics |  genomics |  machine |  learning |  bioinformatics |  machine learning

2. Prenatal exposure on nanoplastics: A study of spatial transcriptomics in hippocampal offspring NSTL国家科技图书文献中心

Tian L. |  Chen J.... -  《Environmental Pollution》 - 2025,366(Feb.1) - 1.1~1.9 - 共9页

摘要: cell type. Spatial transcriptomics was used to |  conclusion, spatial transcriptomics reveals that maternal |  mechanisms of damage are unknown. In this study, spatial |  transcriptomics was used to investigate changes in the | © 2024 Elsevier LtdNanoplastics, as
关键词: Intercellular communication |  Maternal exposure |  Nanoplastics |  Pseudo-time |  Spatial transcriptomics

3. Initial regional cytoarchitectonic differences in dorsal and orbitobasal human developing frontal cortex revealed by spatial transcriptomics NSTL国家科技图书文献中心

Janja,Kopić |  Parthiv,Haldipur... -  《Brain structure & function》 - 2025,230(1) - Article: 13~Article: 13 - 共13页

摘要: spatial information. Here, we employed NanoString GeoMx | ™ Digital Spatial Profiler (DSP) technology to examine | Abstract Early development of the human fetal |  cerebral cortex involves a set of precisely coordinated |  molecular processes that remains rather underexplored
关键词: Regional cytoarchitectonics |  Spatial transcriptomics |  Human fetal brain |  Frontal cortex

4. Spatial Transcriptomics Reveals Cancer and Stromal Cell Heterogeneity Between Center and Invasive Front of Pancreatic Cancer NSTL国家科技图书文献中心

Alver, Tine Norman |  Bergholtz, Helga... -  《Modern pathology》 - 2025,38(6) - Article 100726~Article 100726 - 共12页

摘要: revealed, but the spatial distribution of the |  been characterized. In this study, digital spatial | Intratumor heterogeneity is considered a major |  cause of treatment failure in pancreatic ductal |  adenocarcinoma (PDAC). In recent years, marked heterogeneity at
关键词: pancreatic cancer |  spatial transcriptomics |  cancer associated fibroblasts |  tumor biology

5. Spatial and Single-Cell Transcriptomics Reveals the Regional Division of the Spatial Structure of MASH Fibrosis NSTL国家科技图书文献中心

Li, Jin-zhong |  Yang, Liu... -  《Liver international》 - 2025,45(4) - e16125~e16125 - 共13页

摘要: spatial transcriptomics integrated with single-cell RNA | -seq. Results: Spatial transcriptomics analysis of | Objective: To elucidate the regional |  distribution of metabolic dysfunction-associated |  steatohepatitis (MASH) fibrosis within the liver and to identify
关键词: ADAMTSL2 |  fibrosis |  hepatic stellate cell |  MASH |  spatial transcriptomics

6. Spatiotemporal Cellular Dynamics of Germinal Center Reaction in Coronavirus Disease 2019 Lung-Draining Lymph Node Based on Imaging-Based Spatial Transcriptomics NSTL国家科技图书文献中心

Oh, Taehwan |  Woo, Youngmin... -  《Laboratory investigation》 - 2025,105(1) - 102180~102180 - 共11页

摘要:-based spatial transcriptomics to delineate immune cell |  reinfection. The spatial transcriptome atlas produced herein |  therapeutic interventions in the spatial context. (c) 2024 | Although lymph node structures may be |  compromised in severe SARS-CoV-2 infection, the extent and
关键词: COVID-19 |  germinal center |  lymph node drainage |  nonhuman primates |  SARS-CoV-2 |  spatial transcriptomics

7. Visium spatial transcriptomics and proteomics identifies novel hepatic cell populations and transcriptomic signatures of alcohol-associated hepatitis NSTL国家科技图书文献中心

Gripshover, Tyler C. |  Treves, Rui S.... -  《Alcoholism, clinical and experimental research.》 - 2025,49(1) - 106~116 - 共11页

摘要: subpopulations. This study used a hepatic spatial | ) were used for Visium spatial transcriptomic and | BackgroundAlcohol-associated hepatitis (AH) is |  the clinical manifestation of alcohol-associated |  liver disease (ALD). AH is a complex disease
关键词: alcohol‐associated hepatitis |  proliferating cell nuclear antigen‐positive (PCNA+) hepatocytes |  Visium spatial transcriptomics

8. Integrating Metabolic RNA Labeling-Based Time-Resolved Single-Cell RNA Sequencing with Spatial Transcriptomics for Spatiotemporal Transcriptomic Analysis NSTL国家科技图书文献中心

Xiaoyong Chen |  Shichao Lin... -  《Small Methods》 - 2025,9(3) - 1~14 - 共14页

摘要:-resolved scRNA-seq with spatial transcriptomics is a new | . With spatial transcriptomics, it is further revealed | . However, this technology fails to reveal the spatial | Metabolic RNA labeling-based time-resolved |  single-cell RNA sequencing (scRNA-seq) has provided
关键词: EZH2 |  glioblastoma |  mesenchymal transition |  single-cell |  spatiotemporal

9. Fine localization and functional differentiation of exocarp cell clusters during fruit senescence revealed by single-cell and spatial transcriptomics NSTL国家科技图书文献中心

Jia, Jingyu |  Chen, Enyan... -  《Postharvest Biology and Technology》 - 2025,219 - 共14页

摘要: analysis of scRNA-seq and spatial RNAseq data at | The differentiation trajectories of 13 cell |  clusters in H. undatus during senescence have been |  revealed by single- cell transcriptome (scRNA-seq | ) analysis, and the five cell clusters in the exocarp have
关键词: Flavonoid |  Pseudotime |  Biotic and abiotic stresses |  Differentiation trajectories |  Gene regulatory network (GRN)

10. Spatial diversity of in vivo tissue immunity NSTL国家科技图书文献中心

Miyamoto, Yu |  Ishii, Masaru -  《International immunology.》 - 2025,37(2) - 91~96 - 共6页

摘要: imaging and spatial transcriptomics have revealed the | The immune system exhibits spatial |  spatial heterogeneity of immune cell distribution and | . Recent spatial analyses have suggested that a |  spatial communication between immune cells, environment
关键词: intravital imaging |  spatial transcriptomics |  tissue immunology
检索条件Spatial transcriptomics

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