NSTL国家科技图书文献中心

1. Solution-mediated phase transformation of cocrystals at the solid-liquid interface: Relationships between the supersaturation generation rate and transformation pathway NSTL国家科技图书文献中心

Fan, Runhui | Chen, An ... - 《International Journal of Pharmaceutics》 - 2025,668 - 124969～124969 - 共15页

摘要：Cocrystals easily undergo solution-mediated | phase transformation at the surface of dissolving | new scenario for the phase* transformation of* | buffer, a multistep pathway for phase* transformation of* | center dot H2O. A one-step phase* transformation was*

关键词： Liquiritigenin cocrystal | Eudragit E100 | Coformer | Solution-mediated phase transformation | Solid-liquid interface

2. Intensified solid-state transformation during anti-solvent cocrystallization in flow NSTL国家科技图书文献中心

Gupta D. | Mak A.T.C.... - 《Chemical Engineering and Processing》 - 2025,208 - 共20页

摘要： crystallization. Therefore, intensifying a solution-mediated | phase transformation is important. In this work, the | phase transformation process in the carbamazepine | tank are documented. The phase* transformation process* | © 2024Pharmaceutical cocrystals consist of an

关键词： Cocrystals | Crystallization | Phase purity | Solid-state transformation | Static mixer | Tubular crystallizer

3. Effects of dimethylarsenate coprecipitation with ferrihydrite on Fe (II)-induced mineral transformation and the release of dimethylarsenate NSTL国家科技图书文献中心

Chen, Yi | Quan, Yueyang ... - 《Environmental Pollution》 - 2025,367(Feb.15) - 1.1～1.10 - 共10页

摘要： properties and Fe(II)-induced phase* transformation of DMAs* | ) inhibits the Fh transformation* to goethite. No goethite* | continuously released into the solution, with the released | the Fh aging and transformation* to lepidocrocite and* | mediated by Fe (hydr)oxides in natural environments, and

关键词： Iron (hydr)oxides | Organoarsenicals | Coprecipitation | Mineral transformation | Desorption | RAY-ABSORPTION SPECTROSCOPY | ORGANIC-MATTER | ATR-FTIR | FE(II)-CATALYZED TRANSFORMATION | SURFACE COMPLEXATION...

4. Enhanced dissolution of curcumin-resorcinol cocrystal by the inhibition effect of HPMCAS on solution-mediated phase transformation NSTL国家科技图书文献中心

Wang W. | Lu J.... - 《Journal of Molecular Liquids》 - 2024,403 - 共5页

摘要： solution-mediated phase transformation (SMPT) of | solution at 2 h was nearly 15 μg/mL, which was at least | , while the transformation* was prevented in the presence* | © 2024 Elsevier B.V.The present study aimed to | investigate the inhibition effect of polymers on the

关键词： Cocrystal | Curcumin | Diffusion layer | Precipitation inhibitor | Supersaturation

5. Comprehensive exploration of riboflavin solid forms and preparation mechanism of stable forms NSTL国家科技图书文献中心

Yunxia Shao | Wenjie Kuang ... - 《Chemical Engineering Research & Design: Transactions of the Institution of Chemical Engineers》 - 2024,208 - 303～312 - 共10页

摘要： phase transformation among the riboflavin polymorphs | most frequent form.Consequently,a solution-mediated | phase transformation(SMPT)process was proposed to | crystalline phase impurity of riboflavin in the solid state | marketed in crystalline form.However,the phase

关键词： Riboflavin | polymorphs | Stability | Solution-mediated phase transformation

6. Revealing the mechanism of polymer inhibition of 2,4-dichlorophenoxy-acetic acid Polymorphs phase transition by experimental and molecular dynamics simulation NSTL国家科技图书文献中心

Fang, Lan | Cen, Zhenkai ... - 《Journal of Molecular Liquids》 - 2024,394 - ARTN 123691～ - 共9页 - 被引量：1

摘要： solution-mediated phase transformation makes the precise | preparation of pure metastable forms of drugs by solution | can effectively prevent crystal form transformation | the solution. We performed the induction time and | suggest that polymorph control during the solution

关键词： Polymorph control | Polymer additive | Nucleation inhibition | Growth inhibition | Molecular simulation | CRYSTALLIZATION | TRANSFORMATION | ADDITIVES

7. Insight into the Structure and Property Diversity of Four Nicorandil Oxalate Salt Polymorphs Based on Experiments and Quantum Chemistry Study NSTL国家科技图书文献中心

Wang, Qinglin | Guo, Chunyang ... - 《Crystal growth & design》 - 2024,24(3) - 977～991 - 共15页

摘要： successfully isolated from ethanol/water solution, while the | studies including solvent-mediated* polymorph* | transformation, physical-chemical stability, and intrinsic | dissolution of those polymorphs were conducted. Phase | transformation from S3 to S4 in high-humidity conditions and

关键词： PHARMACEUTICAL SALTS | CRYSTAL | SOLUBILITY | CRYSTALLIZATION | ACID | DRUG | COCRYSTALS | STABILITY | MOLECULES | MECHANISM

8. Mechanistic Insight of Polymer Effects on the Kinetic of Solution-Mediated Phase Transformation of Nitrofurantoin Anhydrate to Monohydrate NSTL国家科技图书文献中心

Xiyan,Wang | Xiaohong,Ji ... - 《Pharmaceutical research》 - 2023,40(6) - 1587～1598 - 共12页 - 被引量：2

摘要：, inhibition of phase* transformation is vital to stabilize* | phase transformation were decreased in the presence of | completely inhibited the phase* transformation of anhydrate* | Abstract Purpose Nitrofurantoin is an | effective antibacterial drug for the treatment of lower

关键词： additives | molecular dynamic simulation | nitrofurantoin anhydrate | nucleation and crystal growth | solution-mediated phase transformation

9. Revealing the role of polymer in the robust preparation of the 2,4-dichlorophenoxyacetic acid metastable crystal form by Al-based image analysis EI 工程索引 NSTL国家科技图书文献中心

Lan Fang | Jian Liu ... - 《Powder Technology: An International Journal on the Science and Technology of Wet and Dry Particulate Systems》 - 2023,413 - 118077,2-11～ - 共11页 - 被引量：5

摘要： solution-mediated phase transformation (SMPT) with the | The selective preparation of pure polymorphs | is of great significance in the pharmaceutical | industry. This work aims to prepare the pure metastable | Form II of the 2,4-dichlorophenoxyacetic acid (2,4-D

关键词： 2,4-dichlorophenoxyacetic acid | Metastable form | Polymorph control | Solution-mediated phase transformation | Image analysis

10. Solid-state characterization of ibuprofen-isonicotinamide cocrystals prepared by electrospraying and solvent evaporation NSTL国家科技图书文献中心

Reza Ghafari | Azin Jahangiri ... - 《Therapeutic delivery》 - 2023,14(2) - 121～138 - 共18页

摘要： size, powder flow, wettability, solution mediated | phase transformation (SMPT), and dissolution rate were | increase in dissolution. Therefore, solution mediated | phase transformation should be considered in | characterization of crystalline phase, production yield, particle

摘要：Cocrystals easily undergo solution-mediated | phase transformation at the surface of dissolving | new scenario for the phase* transformation of* | buffer, a multistep pathway for phase* transformation of* | center dot H2O. A one-step phase* transformation was*

关键词： Liquiritigenin cocrystal | Eudragit E100 | Coformer | Solution-mediated phase transformation | Solid-liquid interface

摘要： crystallization. Therefore, intensifying a solution-mediated | phase transformation is important. In this work, the | phase transformation process in the carbamazepine | tank are documented. The phase* transformation process* | © 2024Pharmaceutical cocrystals consist of an

关键词： Cocrystals | Crystallization | Phase purity | Solid-state transformation | Static mixer | Tubular crystallizer

关键词： Iron (hydr)oxides | Organoarsenicals | Coprecipitation | Mineral transformation | Desorption | RAY-ABSORPTION SPECTROSCOPY | ORGANIC-MATTER | ATR-FTIR | FE(II)-CATALYZED TRANSFORMATION | SURFACE COMPLEXATION...

摘要： solution-mediated phase transformation (SMPT) of | solution at 2 h was nearly 15 μg/mL, which was at least | , while the transformation* was prevented in the presence* | © 2024 Elsevier B.V.The present study aimed to | investigate the inhibition effect of polymers on the

关键词： Cocrystal | Curcumin | Diffusion layer | Precipitation inhibitor | Supersaturation

摘要： phase transformation among the riboflavin polymorphs | most frequent form.Consequently,a solution-mediated | phase transformation(SMPT)process was proposed to | crystalline phase impurity of riboflavin in the solid state | marketed in crystalline form.However,the phase

关键词： Riboflavin | polymorphs | Stability | Solution-mediated phase transformation

摘要： solution-mediated phase transformation makes the precise | preparation of pure metastable forms of drugs by solution | can effectively prevent crystal form transformation | the solution. We performed the induction time and | suggest that polymorph control during the solution

关键词： Polymorph control | Polymer additive | Nucleation inhibition | Growth inhibition | Molecular simulation | CRYSTALLIZATION | TRANSFORMATION | ADDITIVES

摘要： successfully isolated from ethanol/water solution, while the | studies including solvent-mediated* polymorph* | transformation, physical-chemical stability, and intrinsic | dissolution of those polymorphs were conducted. Phase | transformation from S3 to S4 in high-humidity conditions and

关键词： PHARMACEUTICAL SALTS | CRYSTAL | SOLUBILITY | CRYSTALLIZATION | ACID | DRUG | COCRYSTALS | STABILITY | MOLECULES | MECHANISM

摘要：, inhibition of phase* transformation is vital to stabilize* | phase transformation were decreased in the presence of | completely inhibited the phase* transformation of anhydrate* | Abstract Purpose Nitrofurantoin is an | effective antibacterial drug for the treatment of lower

关键词： additives | molecular dynamic simulation | nitrofurantoin anhydrate | nucleation and crystal growth | solution-mediated phase transformation

摘要： solution-mediated phase transformation (SMPT) with the | The selective preparation of pure polymorphs | is of great significance in the pharmaceutical | industry. This work aims to prepare the pure metastable | Form II of the 2,4-dichlorophenoxyacetic acid (2,4-D

关键词： 2,4-dichlorophenoxyacetic acid | Metastable form | Polymorph control | Solution-mediated phase transformation | Image analysis

摘要： size, powder flow, wettability, solution mediated | phase transformation (SMPT), and dissolution rate were | increase in dissolution. Therefore, solution mediated | phase transformation should be considered in | characterization of crystalline phase, production yield, particle

关键词： cocrystal | dissolution | electrospraying | ibuprofen | isonicotinamide | phase transformation

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Cocrystals easily undergo solution-mediated | phase transformation at the surface of dissolving | new scenario for the phase transformation of | buffer, a multistep pathway for phase transformation of | center dot H2O. A one-step phase transformation was

关键词： Liquiritigenin cocrystal | Eudragit E100 | Coformer | Solution-mediated phase transformation | Solid-liquid interface

摘要： crystallization. Therefore, intensifying a solution-mediated | phase transformation is important. In this work, the | phase transformation process in the carbamazepine | tank are documented. The phase transformation process | © 2024Pharmaceutical cocrystals consist of an

关键词： Cocrystals | Crystallization | Phase purity | Solid-state transformation | Static mixer | Tubular crystallizer

关键词： Iron (hydr)oxides | Organoarsenicals | Coprecipitation | Mineral transformation | Desorption | RAY-ABSORPTION SPECTROSCOPY | ORGANIC-MATTER | ATR-FTIR | FE(II)-CATALYZED TRANSFORMATION | SURFACE COMPLEXATION...

摘要： solution-mediated phase transformation (SMPT) of | solution at 2 h was nearly 15 μg/mL, which was at least | , while the transformation was prevented in the presence | © 2024 Elsevier B.V.The present study aimed to | investigate the inhibition effect of polymers on the

关键词： Cocrystal | Curcumin | Diffusion layer | Precipitation inhibitor | Supersaturation

摘要： phase transformation among the riboflavin polymorphs | most frequent form.Consequently,a solution-mediated | phase transformation(SMPT)process was proposed to | crystalline phase impurity of riboflavin in the solid state | marketed in crystalline form.However,the phase

关键词： Riboflavin | polymorphs | Stability | Solution-mediated phase transformation

摘要： solution-mediated phase transformation makes the precise | preparation of pure metastable forms of drugs by solution | can effectively prevent crystal form transformation | the solution. We performed the induction time and | suggest that polymorph control during the solution

关键词： Polymorph control | Polymer additive | Nucleation inhibition | Growth inhibition | Molecular simulation | CRYSTALLIZATION | TRANSFORMATION | ADDITIVES

摘要： successfully isolated from ethanol/water solution, while the | studies including solvent-mediated polymorph | transformation, physical-chemical stability, and intrinsic | dissolution of those polymorphs were conducted. Phase | transformation from S3 to S4 in high-humidity conditions and

关键词： PHARMACEUTICAL SALTS | CRYSTAL | SOLUBILITY | CRYSTALLIZATION | ACID | DRUG | COCRYSTALS | STABILITY | MOLECULES | MECHANISM

摘要：, inhibition of phase transformation is vital to stabilize | phase transformation were decreased in the presence of | completely inhibited the phase transformation of anhydrate | Abstract Purpose Nitrofurantoin is an | effective antibacterial drug for the treatment of lower

关键词： additives | molecular dynamic simulation | nitrofurantoin anhydrate | nucleation and crystal growth | solution-mediated phase transformation

摘要： solution-mediated phase transformation (SMPT) with the | The selective preparation of pure polymorphs | is of great significance in the pharmaceutical | industry. This work aims to prepare the pure metastable | Form II of the 2,4-dichlorophenoxyacetic acid (2,4-D

关键词： 2,4-dichlorophenoxyacetic acid | Metastable form | Polymorph control | Solution-mediated phase transformation | Image analysis

摘要： size, powder flow, wettability, solution mediated | phase transformation (SMPT), and dissolution rate were | increase in dissolution. Therefore, solution mediated | phase transformation should be considered in | characterization of crystalline phase, production yield, particle

关键词： cocrystal | dissolution | electrospraying | ibuprofen | isonicotinamide | phase transformation

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Cocrystals easily undergo solution-mediated | phase transformation at the surface of dissolving | new scenario for the phase* transformation of* | buffer, a multistep pathway for phase* transformation of* | center dot H2O. A one-step phase* transformation was*

摘要： crystallization. Therefore, intensifying a solution-mediated | phase transformation is important. In this work, the | phase transformation process in the carbamazepine | tank are documented. The phase* transformation process* | © 2024Pharmaceutical cocrystals consist of an

摘要： solution-mediated phase transformation (SMPT) of | solution at 2 h was nearly 15 μg/mL, which was at least | , while the transformation* was prevented in the presence* | © 2024 Elsevier B.V.The present study aimed to | investigate the inhibition effect of polymers on the

摘要： successfully isolated from ethanol/water solution, while the | studies including solvent-mediated* polymorph* | transformation, physical-chemical stability, and intrinsic | dissolution of those polymorphs were conducted. Phase | transformation from S3 to S4 in high-humidity conditions and

摘要：, inhibition of phase* transformation is vital to stabilize* | phase transformation were decreased in the presence of | completely inhibited the phase* transformation of anhydrate* | Abstract Purpose Nitrofurantoin is an | effective antibacterial drug for the treatment of lower