NSTL国家科技图书文献中心

1. Equine lentivirus Gag protein degrades mitochondrial antiviral signaling protein via the E3 ubiquitin ligase Smurf1 NSTL国家科技图书文献中心

Chen, Kewei | Zhou, Bingqian ... - 《Journal of Virology》 - 2025,99(1) - e01691-24～e01691-24 - 共25页

摘要： mitochondrial antiviral signaling* protein (MAVS) and* | antiviral signaling* protein (MAVS). However, viruses have* | degradation, and that EIAV Gag protein* recruited the E3* | which protein* domain of Gag could interact with MAVS* | structural protein* Gag in targeting MAVS to counteract*

关键词： lentivirus | EIAV | HIV | MAVS | RLR

2. Plumage polymorphism in the black sparrowhawk (Accipiter melanoleucus) is strongly associated with the expression level of agouti signaling protein NSTL国家科技图书文献中心

Rodseth, Edmund | Amar, Arjun ... - 《The Journal of Heredity》 - 2025,116(3) - 193～207 - 共15页

摘要： MC1R or the agouti signaling* protein (ASIP) genes* | ), tyrosinase (TYR), and tyrosinase-related protein* 1 (TYRP1* | Melanin-based plumage polymorphisms in birds | are often associated with mutations in the | melanogenesis genes, notably the melanocortin-1 receptor (MC1R

关键词： Accipiter | agouti | eumelanin | MC1R | melanogenesis | plumage morph

3. Mitogen-Activated Protein Kinase Phosphatase-5 is Required for TGF-β Signaling Through a JNK-Dependent Pathway NSTL国家科技图书文献中心

Dorry, Sam | Perla, Sravan ... - 《Molecular and Cellular Biology》 - 2025,45(1) - 17～31 - 共15页

摘要：Mitogen-activated protein* kinase (MAPK* | -specificity family of protein* phosphatases that* | signaling, and that this regulation occurs through a JNK | transcriptomic analysis, we identify TGF-beta signaling | -beta signaling. This study elucidates a novel

关键词： Mitogen-activated protein kinase | protein phosphatase | cell signaling | protein phosphorylation | signal transduction

4. Identification of a dual specificity protein phosphatase and its function in regulating innate immune signaling in Crassostrea gigas NSTL国家科技图书文献中心

Huo, Chuncao | Liu, Yaqiong ... - 《Fish & Shellfish Immunology》 - 2025,162 - 共10页

摘要： resistance. Dual-specificity protein* phosphatases (DUSPs* | ) play critical roles in regulating cellular signaling | its regulatory role in innate immune signaling* in C* | protein. CgDUSP4 was highly expressed in hemocytes and | . Subcellular localization analysis revealed that the protein

关键词： Crassostrea gigas | Dual specificity protein phosphatase | MAPK | Innate immune signaling regulation | Dephosphorylation

5. Disruption of ATR Signaling by Epstein–Barr Virus Latent Membrane Protein 1 Sensitizes Nasopharyngeal Carcinoma Cells to Cisplatin NSTL国家科技图书文献中心

Gabriella Zarkovic | Phillip Ziegler ... - 《Journal of Medical Virology》 - 2025,97(5) - e70407～e70407 - 共12页

摘要： oncoprotein, latent membrane protein* 1 (LMP1), perturbs DNA* | damage response (DDR) signaling, activation of cell | DDR signaling* and hypersensitivity by LMP1 or ATR* | ABSTRACT Nasopharyngeal carcinoma (NPC) occurs | with high incidence in Southeast Asia where almost

关键词： DNA damage response signaling | Epstein–Barr virus | latent membrane protein 1 | nasopharyngeal carcinoma

6. Early-Life Stress Influences the Transcriptional Activation of Alpha-2A Adrenergic Receptor and Associated Protein Kinase A Signaling Molecules in the Frontal Cortex of Rats NSTL国家科技图书文献中心

Ali, Sarah | Dwivedi, Yogesh - 《Molecular Neurobiology》 - 2025,62(4) - 5297～5310 - 共14页

摘要： subsequent deficits in norepinephrine (NE) signaling* have* | receptor and its downstream second messenger signaling | signaling cascade. To do so, we studied expression levels | ]), and downstream protein* kinase A (PKA) catalytic* | Early life is a highly sensitive period

关键词： Early-life stress | Alpha-2A adrenergic receptor | Protein kinase A | Rat frontal cortex | Signaling system

7. The S273R protein of African swine fever virus antagonizes the canonical NF- κ B signaling pathway by I κ B α NSTL国家科技图书文献中心

Ren, Haojie | Shi, Lan-Fang ... - 《Journal of Virology》 - 2025,99(5) - e0222524～e0222524 - 共21页

摘要：, especially the NF-kappa B signaling* pathway, play central* | study, we identified the ASFV S273R protein* (pS273R* | signaling pathway independently of its protease activity | beta-triggered NF-kappa B signaling* pathway in* | inhibition of the NF-kappa B signaling* pathway. These*

关键词： African swine fever virus | canonical NF- kappa B signaling pathway | S273R protein | I kappa B alpha | inflammatory responses

8. The structural protein VP3 of enterovirus D68 interacts with MAVS to inhibit the NF-κB signaling pathway NSTL国家科技图书文献中心

Chen, Honghua | Huang, Mengqian ... - 《Journal of Virology》 - 2025,99(4) - e0016325～e0016325 - 共17页

摘要： indispensable for mitochondrial antiviral signaling protein | immune evasion mediated by EV-D68 structural protein | protein VP3 targets specifically the interferon | regulatory factor 7 to inhibit type I interferon signaling | (MAVS)-activated type I interferon signaling

关键词： EV-D68 | VP3 | MAVS | NF-kappa B | mitochondrial damage

9. G protein-coupled estrogen receptor biased signaling in health and disease NSTL国家科技图书文献中心

Bushi, Aisha | Ma, Yixuan ... - 《Pharmacology and Therapeutics》 - 2025,269 - 108822～108822 - 共20页

摘要：G protein-coupled estrogen receptor (GPER | signaling, influencing diverse physiological processes and | , GPER exhibits biased signaling, wherein ligand | explores the nuanced mechanisms of biased signaling | implications, biased signaling* through GPER remains*

关键词： GPER | Biased signaling | Cellular pathways | Therapeutic implications | Precision medicine

10. HSF1 and CPSF1 affect milk fat and protein synthesis by regulating the AKT/mTOR signaling pathway NSTL国家科技图书文献中心

Chen, Zhujun | Zhang, Xinyi ... - 《Journal of Animal Science》 - 2025,103 - 共11页

摘要： associated with milk fat and protein* percentages. However* | , their roles in milk fat and protein* synthesis and the* | milk fat and milk protein* synthesis in MAC-T cells* | signaling pathway, one of the most important pathways for | fat and protein* synthesis, through its interaction*

关键词： lentivirus | EIAV | HIV | MAVS | RLR

摘要： MC1R or the agouti signaling* protein (ASIP) genes* | ), tyrosinase (TYR), and tyrosinase-related protein* 1 (TYRP1* | Melanin-based plumage polymorphisms in birds | are often associated with mutations in the | melanogenesis genes, notably the melanocortin-1 receptor (MC1R

关键词： Accipiter | agouti | eumelanin | MC1R | melanogenesis | plumage morph

摘要：Mitogen-activated protein* kinase (MAPK* | -specificity family of protein* phosphatases that* | signaling, and that this regulation occurs through a JNK | transcriptomic analysis, we identify TGF-beta signaling | -beta signaling. This study elucidates a novel

关键词： Mitogen-activated protein kinase | protein phosphatase | cell signaling | protein phosphorylation | signal transduction

关键词： Crassostrea gigas | Dual specificity protein phosphatase | MAPK | Innate immune signaling regulation | Dephosphorylation

摘要： oncoprotein, latent membrane protein* 1 (LMP1), perturbs DNA* | damage response (DDR) signaling, activation of cell | DDR signaling* and hypersensitivity by LMP1 or ATR* | ABSTRACT Nasopharyngeal carcinoma (NPC) occurs | with high incidence in Southeast Asia where almost

关键词： DNA damage response signaling | Epstein–Barr virus | latent membrane protein 1 | nasopharyngeal carcinoma

摘要： subsequent deficits in norepinephrine (NE) signaling* have* | receptor and its downstream second messenger signaling | signaling cascade. To do so, we studied expression levels | ]), and downstream protein* kinase A (PKA) catalytic* | Early life is a highly sensitive period

关键词： Early-life stress | Alpha-2A adrenergic receptor | Protein kinase A | Rat frontal cortex | Signaling system

摘要：, especially the NF-kappa B signaling* pathway, play central* | study, we identified the ASFV S273R protein* (pS273R* | signaling pathway independently of its protease activity | beta-triggered NF-kappa B signaling* pathway in* | inhibition of the NF-kappa B signaling* pathway. These*

关键词： African swine fever virus | canonical NF- kappa B signaling pathway | S273R protein | I kappa B alpha | inflammatory responses

摘要： indispensable for mitochondrial antiviral signaling protein | immune evasion mediated by EV-D68 structural protein | protein VP3 targets specifically the interferon | regulatory factor 7 to inhibit type I interferon signaling | (MAVS)-activated type I interferon signaling

关键词： EV-D68 | VP3 | MAVS | NF-kappa B | mitochondrial damage

摘要：G protein-coupled estrogen receptor (GPER | signaling, influencing diverse physiological processes and | , GPER exhibits biased signaling, wherein ligand | explores the nuanced mechanisms of biased signaling | implications, biased signaling* through GPER remains*

关键词： GPER | Biased signaling | Cellular pathways | Therapeutic implications | Precision medicine

摘要： associated with milk fat and protein* percentages. However* | , their roles in milk fat and protein* synthesis and the* | milk fat and milk protein* synthesis in MAC-T cells* | signaling pathway, one of the most important pathways for | fat and protein* synthesis, through its interaction*

关键词： AKT/mTOR | CPSF1 | HSF1 | milk fat | milk protein

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： mitochondrial antiviral signaling protein (MAVS) and | antiviral signaling protein (MAVS). However, viruses have | degradation, and that EIAV Gag protein recruited the E3 | which protein domain of Gag could interact with MAVS | structural protein Gag in targeting MAVS to counteract

关键词： lentivirus | EIAV | HIV | MAVS | RLR

摘要： MC1R or the agouti signaling protein (ASIP) genes | ), tyrosinase (TYR), and tyrosinase-related protein 1 (TYRP1 | Melanin-based plumage polymorphisms in birds | are often associated with mutations in the | melanogenesis genes, notably the melanocortin-1 receptor (MC1R

关键词： Accipiter | agouti | eumelanin | MC1R | melanogenesis | plumage morph

摘要：Mitogen-activated protein kinase (MAPK | -specificity family of protein phosphatases that | signaling, and that this regulation occurs through a JNK | transcriptomic analysis, we identify TGF-beta signaling | -beta signaling. This study elucidates a novel

关键词： Mitogen-activated protein kinase | protein phosphatase | cell signaling | protein phosphorylation | signal transduction

摘要： resistance. Dual-specificity protein phosphatases (DUSPs | ) play critical roles in regulating cellular signaling | its regulatory role in innate immune signaling in C | protein. CgDUSP4 was highly expressed in hemocytes and | . Subcellular localization analysis revealed that the protein

关键词： Crassostrea gigas | Dual specificity protein phosphatase | MAPK | Innate immune signaling regulation | Dephosphorylation

摘要： oncoprotein, latent membrane protein 1 (LMP1), perturbs DNA | damage response (DDR) signaling, activation of cell | DDR signaling and hypersensitivity by LMP1 or ATR | ABSTRACT Nasopharyngeal carcinoma (NPC) occurs | with high incidence in Southeast Asia where almost

关键词： DNA damage response signaling | Epstein–Barr virus | latent membrane protein 1 | nasopharyngeal carcinoma

摘要： subsequent deficits in norepinephrine (NE) signaling have | receptor and its downstream second messenger signaling | signaling cascade. To do so, we studied expression levels | ]), and downstream protein kinase A (PKA) catalytic | Early life is a highly sensitive period

关键词： Early-life stress | Alpha-2A adrenergic receptor | Protein kinase A | Rat frontal cortex | Signaling system

摘要：, especially the NF-kappa B signaling pathway, play central | study, we identified the ASFV S273R protein (pS273R | signaling pathway independently of its protease activity | beta-triggered NF-kappa B signaling pathway in | inhibition of the NF-kappa B signaling pathway. These

关键词： African swine fever virus | canonical NF- kappa B signaling pathway | S273R protein | I kappa B alpha | inflammatory responses

摘要： indispensable for mitochondrial antiviral signaling protein | immune evasion mediated by EV-D68 structural protein | protein VP3 targets specifically the interferon | regulatory factor 7 to inhibit type I interferon signaling | (MAVS)-activated type I interferon signaling

关键词： EV-D68 | VP3 | MAVS | NF-kappa B | mitochondrial damage

摘要：G protein-coupled estrogen receptor (GPER | signaling, influencing diverse physiological processes and | , GPER exhibits biased signaling, wherein ligand | explores the nuanced mechanisms of biased signaling | implications, biased signaling through GPER remains

关键词： GPER | Biased signaling | Cellular pathways | Therapeutic implications | Precision medicine

摘要： associated with milk fat and protein percentages. However | , their roles in milk fat and protein synthesis and the | milk fat and milk protein synthesis in MAC-T cells | signaling pathway, one of the most important pathways for | fat and protein synthesis, through its interaction

关键词： AKT/mTOR | CPSF1 | HSF1 | milk fat | milk protein

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： MC1R or the agouti signaling* protein (ASIP) genes* | ), tyrosinase (TYR), and tyrosinase-related protein* 1 (TYRP1* | Melanin-based plumage polymorphisms in birds | are often associated with mutations in the | melanogenesis genes, notably the melanocortin-1 receptor (MC1R

摘要：Mitogen-activated protein* kinase (MAPK* | -specificity family of protein* phosphatases that* | signaling, and that this regulation occurs through a JNK | transcriptomic analysis, we identify TGF-beta signaling | -beta signaling. This study elucidates a novel

摘要： oncoprotein, latent membrane protein* 1 (LMP1), perturbs DNA* | damage response (DDR) signaling, activation of cell | DDR signaling* and hypersensitivity by LMP1 or ATR* | ABSTRACT Nasopharyngeal carcinoma (NPC) occurs | with high incidence in Southeast Asia where almost

摘要： subsequent deficits in norepinephrine (NE) signaling* have* | receptor and its downstream second messenger signaling | signaling cascade. To do so, we studied expression levels | ]), and downstream protein* kinase A (PKA) catalytic* | Early life is a highly sensitive period

摘要：, especially the NF-kappa B signaling* pathway, play central* | study, we identified the ASFV S273R protein* (pS273R* | signaling pathway independently of its protease activity | beta-triggered NF-kappa B signaling* pathway in* | inhibition of the NF-kappa B signaling* pathway. These*

摘要：G protein-coupled estrogen receptor (GPER | signaling, influencing diverse physiological processes and | , GPER exhibits biased signaling, wherein ligand | explores the nuanced mechanisms of biased signaling | implications, biased signaling* through GPER remains*

摘要： associated with milk fat and protein* percentages. However* | , their roles in milk fat and protein* synthesis and the* | milk fat and milk protein* synthesis in MAC-T cells* | signaling pathway, one of the most important pathways for | fat and protein* synthesis, through its interaction*