NSTL国家科技图书文献中心

1. TRP Channels in Excitotoxicity NSTL国家科技图书文献中心

Zong, Pengyu | Legere, Nicholas ... - 《The Neuroscientist》 - 2025,31(1) - 80～97 - 共18页

摘要：Glutamate excitotoxicity* is a central* | GluD receptors. Thus, excitotoxicity* could be* | excitotoxicity in human patients, mainly due to the limited | excitotoxicity. Transient receptor potential (TRP) channels | , including excitotoxicity. In this review, our focus

关键词： excitotoxicity | stroke | epilepsy | TRP channels | TRPM2 | TRPM4 | TRPCs | TRPV4

2. Multi-Omic Analysis of Glutamate Excitotoxicity in Primary Neuronal Cultures NSTL国家科技图书文献中心

Jennifer H. Nguyen | Xiaolu Zhang ... - 《Journal of neurochemistry.》 - 2025,169(6) - e70110～e70110 - 共19页

摘要：Glutamate excitotoxicity* plays a critical role* | -induced excitotoxicity. Intermediate doses of glutamate | excitotoxicity induces molecular changes at the transcriptome | in neurodegeneration by triggering NMDA receptor | hyperactivation, leading to elevated synaptic calcium levels and

关键词： MAPK signaling; glutamate excitotoxicity; kinomics; multiomics; transcriptomics.

3. Excitatory amino acids as therapeutic agents: Reversing neurodegenerative trajectory by tackling excitotoxicity NSTL国家科技图书文献中心

Dhurandhar, Yogita | Tomar, Shubham ... - 《Neurological sciences》 - 2025,46(2) - 549～560 - 共12页

摘要： mitigating excitotoxicity-a process characterized by | Neurodegenerative diseases pose significant | challenges to healthcare systems globally due to their | complex etiology and relentless progression, often | rendering conventional treatments ineffective. Recent

关键词： D-amino acids | Neurotoxicity | Excitotoxicity | Remission | Excitatory

4. Reduction in presynaptic glutamate release and the prevention of glutamate excitotoxicity by lupeol in rats NSTL国家科技图书文献中心

Lu, Cheng-Wei | Lin, Tzu-Yu ... - 《Neurochemistry International》 - 2025,185 - Article 105951～Article 105951 - 共9页

摘要： the excitotoxicity* induced by kainic acid (KA) in* | . In the KA-induced acute excitotoxicity* model* | effect by reducing glutamate excitotoxicity* through the* | the treatment of glutamatergic excitotoxicity* and* | This study aimed to investigate whether lupeol

关键词： Lupeol | P/Q-type Ca2+channel | Glutamate release inhibition | Glutamate excitotoxicity | Kainic acid | Cortex

5. Age-dependent changes in NMDA-induced excitotoxicity and neuromodulatory effects of kynurenic acid and its analogue in mouse brain slices NSTL国家科技图书文献中心

Balog, Emma | Jenei, Gyula ... - 《Neuroscience Letters》 - 2025,854 - Article 138220～Article 138220 - 共7页

摘要： various animal models. Glutamate-induced excitotoxicity | excitotoxicity model to investigate the neuromodulatory agents | its analogue, SZR72 on NMDA-induced excitotoxicity | different ages using an in vitro NMDA excitotoxicity* model.* | Kynurenic acid (KYNA) is one of the main

关键词： Kynurenic acid | Kynurenic acid analogue | N-methyl-D-aspartate | Mouse acute brain slice preparations | Excitotoxicity

6. Protective effect of Apelin-13 on D-glutamic acid-induced excitotoxicity in SH-SY5Y cell line: An in-vitro study NSTL国家科技图书文献中心

Oruc, Kadriye Yagmur | Agturk, Gokhan ... - 《Neuropeptides》 - 2025,109 - Article 102483～Article 102483 - 共16页

摘要：Excitotoxicity, resulting from excessive | excitotoxicity in SH-SY5Y human neuroblastoma cells, an in | excitotoxicity-induced neuronal damage, emphasizing its ability | accumulation of glutamate in the extracellular space, leads | to neuronal cell death. This study investigates the

关键词： Apelin-13 | Excitotoxicity | D-glutamic acid | Neuroinflammation | SH-SY5Y cell line | Neurotoxicity

7. Differential molecular mechanism of the neuroprotective activity of mulberries (Morus Alba & Morus Nigra) against glutamate induced-excitotoxicity on cortical neurons NSTL国家科技图书文献中心

Olfa Rebai | Vicky Gomez Sanchez ... - 《Journal of Berry Research》 - 2025,15(2) - 120～133 - 共14页

摘要： against Glutamate excitotoxicity. Protective effect of | MAE against Glutamate excitotoxicity. Our data | Neurotoxicity induced by glutamate is used | herein in his study for testing the neuroprotective | effects of Tunisian mulberries fruits extracts from two

关键词： HPLC- LCMS | neuroprotection | oxidative stress | molecular mechanism | glutamate excitotoxicity | MAPK | antioxidant system | apoptosis

8. Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment NSTL国家科技图书文献中心

Moriarty, Colin | Gupta, Natasha ... - 《Cell biology international.》 - 2025,49(5) - 421～434 - 共14页

摘要： as glutamate excitotoxicity, leading to neuronal | damage. This excitotoxicity* contributes to neuronal* | used to counteract glutamate excitotoxicity, but its | efficacy in directly combating excitotoxicity* is limited* | reducing glutamate excitotoxicity* in glioblastoma. In*

关键词： cystine-glutamate antiporter | GLAST | glioblastoma | glutamate | mGlu3R | temozolomide

9. Neurological Manifestations Following Traumatic Brain Injury: Role of Behavioral, Neuroinflammation, Excitotoxicity, Nrf-2 and Nitric Oxide NSTL国家科技图书文献中心

Goyal, Lav | Singh, Shamsher - 《CNS & neurological disorders drug targets》 - 2025,24(1) - 47～59 - 共13页 - 被引量：1

摘要：Traumatic Brain Injury (TBI) is attributed to | a forceful impact on the brain caused by sharp | , penetrating bodies, like bullets and any sharp object. Some | popular instances like falls, traffic accidents | , physical assaults, and athletic injuries frequently cause

关键词： Traumatic brain injury | behavioral changes | neuro-inflammation | excitotoxic changes | Nrf-2 | and nitric oxide

10. Environmentally relevant concentrations lithium exposure induces neurotoxicity in yellowstripe goby (Mugilogobius chulae): Responses of BDNF/AKT/FoxOs in regulating glutamate excitotoxicity and mitochondrial function NSTL国家科技图书文献中心

Gong, Weibo | Zhao, Yufei ... - 《Aquatic Toxicology》 - 2025,281 - 共9页

摘要：The wide application of lithium in green | energy and clinical psychiatry results in ubiquitous | occurrence of lithium in aquatic environments. However | , researches on the toxicity of lithium are largely confined | to acute and/or high-dose scenarios, with

摘要：Glutamate excitotoxicity* is a central* | GluD receptors. Thus, excitotoxicity* could be* | excitotoxicity in human patients, mainly due to the limited | excitotoxicity. Transient receptor potential (TRP) channels | , including excitotoxicity. In this review, our focus

关键词： excitotoxicity | stroke | epilepsy | TRP channels | TRPM2 | TRPM4 | TRPCs | TRPV4

摘要：Glutamate excitotoxicity* plays a critical role* | -induced excitotoxicity. Intermediate doses of glutamate | excitotoxicity induces molecular changes at the transcriptome | in neurodegeneration by triggering NMDA receptor | hyperactivation, leading to elevated synaptic calcium levels and

关键词： MAPK signaling; glutamate excitotoxicity; kinomics; multiomics; transcriptomics.

摘要： mitigating excitotoxicity-a process characterized by | Neurodegenerative diseases pose significant | challenges to healthcare systems globally due to their | complex etiology and relentless progression, often | rendering conventional treatments ineffective. Recent

关键词： D-amino acids | Neurotoxicity | Excitotoxicity | Remission | Excitatory

摘要： the excitotoxicity* induced by kainic acid (KA) in* | . In the KA-induced acute excitotoxicity* model* | effect by reducing glutamate excitotoxicity* through the* | the treatment of glutamatergic excitotoxicity* and* | This study aimed to investigate whether lupeol

关键词： Lupeol | P/Q-type Ca2+channel | Glutamate release inhibition | Glutamate excitotoxicity | Kainic acid | Cortex

摘要： various animal models. Glutamate-induced excitotoxicity | excitotoxicity model to investigate the neuromodulatory agents | its analogue, SZR72 on NMDA-induced excitotoxicity | different ages using an in vitro NMDA excitotoxicity* model.* | Kynurenic acid (KYNA) is one of the main

关键词： Kynurenic acid | Kynurenic acid analogue | N-methyl-D-aspartate | Mouse acute brain slice preparations | Excitotoxicity

摘要：Excitotoxicity, resulting from excessive | excitotoxicity in SH-SY5Y human neuroblastoma cells, an in | excitotoxicity-induced neuronal damage, emphasizing its ability | accumulation of glutamate in the extracellular space, leads | to neuronal cell death. This study investigates the

关键词： Apelin-13 | Excitotoxicity | D-glutamic acid | Neuroinflammation | SH-SY5Y cell line | Neurotoxicity

摘要： against Glutamate excitotoxicity. Protective effect of | MAE against Glutamate excitotoxicity. Our data | Neurotoxicity induced by glutamate is used | herein in his study for testing the neuroprotective | effects of Tunisian mulberries fruits extracts from two

关键词： HPLC- LCMS | neuroprotection | oxidative stress | molecular mechanism | glutamate excitotoxicity | MAPK | antioxidant system | apoptosis

摘要： as glutamate excitotoxicity, leading to neuronal | damage. This excitotoxicity* contributes to neuronal* | used to counteract glutamate excitotoxicity, but its | efficacy in directly combating excitotoxicity* is limited* | reducing glutamate excitotoxicity* in glioblastoma. In*

关键词： cystine-glutamate antiporter | GLAST | glioblastoma | glutamate | mGlu3R | temozolomide

摘要：Traumatic Brain Injury (TBI) is attributed to | a forceful impact on the brain caused by sharp | , penetrating bodies, like bullets and any sharp object. Some | popular instances like falls, traffic accidents | , physical assaults, and athletic injuries frequently cause

关键词： Traumatic brain injury | behavioral changes | neuro-inflammation | excitotoxic changes | Nrf-2 | and nitric oxide

摘要：The wide application of lithium in green | energy and clinical psychiatry results in ubiquitous | occurrence of lithium in aquatic environments. However | , researches on the toxicity of lithium are largely confined | to acute and/or high-dose scenarios, with

关键词： Lithium | Mugilogobius chulae | Neurotoxicity | Mitochondria | Glutamatergic receptors

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Glutamate excitotoxicity is a central | GluD receptors. Thus, excitotoxicity could be | excitotoxicity in human patients, mainly due to the limited | excitotoxicity. Transient receptor potential (TRP) channels | , including excitotoxicity. In this review, our focus

关键词： excitotoxicity | stroke | epilepsy | TRP channels | TRPM2 | TRPM4 | TRPCs | TRPV4

摘要：Glutamate excitotoxicity plays a critical role | -induced excitotoxicity. Intermediate doses of glutamate | excitotoxicity induces molecular changes at the transcriptome | in neurodegeneration by triggering NMDA receptor | hyperactivation, leading to elevated synaptic calcium levels and

关键词： MAPK signaling; glutamate excitotoxicity; kinomics; multiomics; transcriptomics.

摘要： mitigating excitotoxicity-a process characterized by | Neurodegenerative diseases pose significant | challenges to healthcare systems globally due to their | complex etiology and relentless progression, often | rendering conventional treatments ineffective. Recent

关键词： D-amino acids | Neurotoxicity | Excitotoxicity | Remission | Excitatory

摘要： the excitotoxicity induced by kainic acid (KA) in | . In the KA-induced acute excitotoxicity model | effect by reducing glutamate excitotoxicity through the | the treatment of glutamatergic excitotoxicity and | This study aimed to investigate whether lupeol

关键词： Lupeol | P/Q-type Ca2+channel | Glutamate release inhibition | Glutamate excitotoxicity | Kainic acid | Cortex

摘要： various animal models. Glutamate-induced excitotoxicity | excitotoxicity model to investigate the neuromodulatory agents | its analogue, SZR72 on NMDA-induced excitotoxicity | different ages using an in vitro NMDA excitotoxicity model. | Kynurenic acid (KYNA) is one of the main

关键词： Kynurenic acid | Kynurenic acid analogue | N-methyl-D-aspartate | Mouse acute brain slice preparations | Excitotoxicity

摘要：Excitotoxicity, resulting from excessive | excitotoxicity in SH-SY5Y human neuroblastoma cells, an in | excitotoxicity-induced neuronal damage, emphasizing its ability | accumulation of glutamate in the extracellular space, leads | to neuronal cell death. This study investigates the

关键词： Apelin-13 | Excitotoxicity | D-glutamic acid | Neuroinflammation | SH-SY5Y cell line | Neurotoxicity

摘要： against Glutamate excitotoxicity. Protective effect of | MAE against Glutamate excitotoxicity. Our data | Neurotoxicity induced by glutamate is used | herein in his study for testing the neuroprotective | effects of Tunisian mulberries fruits extracts from two

关键词： HPLC- LCMS | neuroprotection | oxidative stress | molecular mechanism | glutamate excitotoxicity | MAPK | antioxidant system | apoptosis

摘要： as glutamate excitotoxicity, leading to neuronal | damage. This excitotoxicity contributes to neuronal | used to counteract glutamate excitotoxicity, but its | efficacy in directly combating excitotoxicity is limited | reducing glutamate excitotoxicity in glioblastoma. In

关键词： cystine-glutamate antiporter | GLAST | glioblastoma | glutamate | mGlu3R | temozolomide

摘要：Traumatic Brain Injury (TBI) is attributed to | a forceful impact on the brain caused by sharp | , penetrating bodies, like bullets and any sharp object. Some | popular instances like falls, traffic accidents | , physical assaults, and athletic injuries frequently cause

关键词： Traumatic brain injury | behavioral changes | neuro-inflammation | excitotoxic changes | Nrf-2 | and nitric oxide

摘要：The wide application of lithium in green | energy and clinical psychiatry results in ubiquitous | occurrence of lithium in aquatic environments. However | , researches on the toxicity of lithium are largely confined | to acute and/or high-dose scenarios, with

关键词： Lithium | Mugilogobius chulae | Neurotoxicity | Mitochondria | Glutamatergic receptors

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Glutamate excitotoxicity* is a central* | GluD receptors. Thus, excitotoxicity* could be* | excitotoxicity in human patients, mainly due to the limited | excitotoxicity. Transient receptor potential (TRP) channels | , including excitotoxicity. In this review, our focus

摘要：Glutamate excitotoxicity* plays a critical role* | -induced excitotoxicity. Intermediate doses of glutamate | excitotoxicity induces molecular changes at the transcriptome | in neurodegeneration by triggering NMDA receptor | hyperactivation, leading to elevated synaptic calcium levels and

摘要： the excitotoxicity* induced by kainic acid (KA) in* | . In the KA-induced acute excitotoxicity* model* | effect by reducing glutamate excitotoxicity* through the* | the treatment of glutamatergic excitotoxicity* and* | This study aimed to investigate whether lupeol

摘要： various animal models. Glutamate-induced excitotoxicity | excitotoxicity model to investigate the neuromodulatory agents | its analogue, SZR72 on NMDA-induced excitotoxicity | different ages using an in vitro NMDA excitotoxicity* model.* | Kynurenic acid (KYNA) is one of the main

摘要： as glutamate excitotoxicity, leading to neuronal | damage. This excitotoxicity* contributes to neuronal* | used to counteract glutamate excitotoxicity, but its | efficacy in directly combating excitotoxicity* is limited* | reducing glutamate excitotoxicity* in glioblastoma. In*