NSTL国家科技图书文献中心

1. A cell-based drug screening assay on a centrifugal platform NSTL国家科技图书文献中心

Shih, Chia-Tse | Guo, Huan-Jun ... - 《Biofabrication》 - 2025,17(2) - 共14页

摘要：Drug screening is an indispensable procedure | . Microfluidic technology enables drug* screening to be* | drug screening is presented. The microfluidic | in drug* development and pharmaceutical research* | . For cell-based drug* testing, cells were treated with*

关键词： cell-based drug screening assay | concentration gradient generator | centrifugal microfluidics

2. Drug screening approaches for small-molecule compounds in cancer-targeted therapy NSTL国家科技图书文献中心

Zhao, Yelin | Yuan, Chenyu ... - 《Journal of drug targeting》 - 2025,33(3) - 368～383 - 共16页

摘要： past decade, advances in covalent drug* discovery have* | . Researchers are paying more attention to refining drug | screening methods aiming for high throughput, fast speed | facilitated by significantly reducing screening* time and* | screening small-molecule compounds in targeted cancer

关键词： Drug screening | small-molecule compounds | targeted cancer therapy | target-based drug screening | phenotype-based drug screening | computer-aided drug discovery

3. An object detection-based model for automated screening of stem-cells senescence during drug screening NSTL国家科技图书文献中心

Ren, Yu | Song, Youyi ... - 《Neural Networks》 - 2025,183 - Article 106940～Article 106940 - 共15页

摘要：, providing potential for anti-senescent drug* screening. Our* | Deep learning-based cell senescence detection | is crucial for accurate quantitative analysis of | senescence assessment. However, senescent cells are small | in size and have little differences in appearance

关键词： Anti-senescence drug screening | Deep learning | Object detection | Swin Transformer

4. Recent Developments in Glioblastoma-On-A-Chip for Advanced Drug Screening Applications NSTL国家科技图书文献中心

Maity, Surjendu | Bhuyan, Tamanna ... - 《Small》 - 2025,21(1) - n/a～n/a - 共31页

摘要： modeling, drug* screening, and personalized medicine* | etiology and revolutionize drug* development by reducing* | and their applications is reported for drug | screening and discussed current challenges and potential | Glioblastoma (GBM) is an aggressive form of

关键词： disease modeling | drug screening | GBM | GBM-on-a-chip | tumor microenvironment | GBM‐on‐a‐chip

5. Technical note: Evaluation of a transportable linear ion trap mass spectrometer for seized drug screening operated under controlled laboratory conditions NSTL国家科技图书文献中心

Couch, Alleigh N. | Chang, Christina ... - 《Forensic science international》 - 2025,367 - 112381～112381 - 共6页

摘要： instruments for on-site or mobile laboratory drug screening | promise for rapid seized drug* screening under controlled* | Increasing seized drug* casework submissions* | and challenges with rapidly triaging seized drug | chemical ionization (TDAPCI) source for seized drug

关键词： Seized drug screening | Controlled substances | Atmospheric pressure chemical ionization | Linear ion trap | Tandem mass spectrometry | Validation

6. Droplet-based 3D bioprinting for drug delivery and screening NSTL国家科技图书文献中心

Xu, Heqi | Zhang, Shaokun ... - 《Advanced drug delivery reviews》 - 2025,217 - 115486～115486 - 共20页

摘要： therapeutic effects. Besides, drug* screening is a high-cost* | throughput drug* screening, respectively. This review* | in drug* delivery and screening and discusses the* | ensuring drug* screening efficiency and efficacy.* | approaches to facilitate drug* development rate. Benefiting*

关键词： Droplet-based 3D bioprinting | Inkjet 3D bioprinting | Personalized medicine | Drug carriers | Drug delivery | Drug screening | Tissue models

7. Advancing the in vitro drug screening models: Microbiome as a componentof tissue-engineered skin NSTL国家科技图书文献中心

Vsevolod V. Shishkov | Polina Yu Bikmulina ... - 《Bioprinting》 - 2025,45 - Advancing the in vitro/1～Advancing the in vitro/15 - 共15页

摘要： clinical practice and drug* screening. The development of* | models employed in drug* screening typically lack a* | Currently, in vitro skin models are among the | most advanced and frequently utilized tools in | these models often involves the use of skin organoids

关键词： Skin | Skin model | Microbiome | Tissue engineering | Bioprinting

8. High-throughput solutions in tumor organoids: from culture to drug screening NSTL国家科技图书文献中心

Zuo, Jianing | Fang, Yanhua ... - 《Stem Cells》 - 2025,43(1) - sxae070～sxae070 - 共12页

摘要： culture to drug* screening. Furthermore, we explore* | single-cell preparation, organoid culture, and drug | screening with the ultimate goal of ensuring the | Tumor organoids have emerged as an ideal in | vitro model for patient-derived tissues, as they

关键词： tumor organoids | high-throughput technology | individualized medicine | microfluidics | 3D printing | organs-on-chips

9. Techniques for improving the specificity of sandwich enzyme‐linked immunosorbent assay‐based drug screening NSTL国家科技图书文献中心

Rohan Steel | Antony Botteon ... - 《Drug testing and analysis》 - 2025,17(3/4) - 555～560 - 共6页

摘要： drug screening by racing laboratories but are known | ELISA screening* results are typically produced by non* | degradation. While confirmation of drug* positives can be* | inaccurate ELISA screening* results represents an* | particularly true in the case of rhEPO screening* using*

关键词： ELISA screening | recombinant human erythropoietin | specificity

10. Construction of oral squamous cell carcinoma organoids in vitro 3D‐culture for drug screening NSTL国家科技图书文献中心

Xin‐Yuan Zhang | Yi Sui ... - 《Oral diseases》 - 2025,31(1) - 99～109 - 共11页

摘要： personalized in vitro drug* sensitivity screening was* | assess drug* responsiveness. Methods We screened and* | cultured organoids and source tissues. Drug* sensitivity* | , highlighting their value for assessing drug* sensitivity* | Abstract Objective Patient‐derived organoids

摘要：Drug screening is an indispensable procedure | . Microfluidic technology enables drug* screening to be* | drug screening is presented. The microfluidic | in drug* development and pharmaceutical research* | . For cell-based drug* testing, cells were treated with*

关键词： cell-based drug screening assay | concentration gradient generator | centrifugal microfluidics

摘要： past decade, advances in covalent drug* discovery have* | . Researchers are paying more attention to refining drug | screening methods aiming for high throughput, fast speed | facilitated by significantly reducing screening* time and* | screening small-molecule compounds in targeted cancer

关键词： Drug screening | small-molecule compounds | targeted cancer therapy | target-based drug screening | phenotype-based drug screening | computer-aided drug discovery

摘要：, providing potential for anti-senescent drug* screening. Our* | Deep learning-based cell senescence detection | is crucial for accurate quantitative analysis of | senescence assessment. However, senescent cells are small | in size and have little differences in appearance

关键词： Anti-senescence drug screening | Deep learning | Object detection | Swin Transformer

摘要： modeling, drug* screening, and personalized medicine* | etiology and revolutionize drug* development by reducing* | and their applications is reported for drug | screening and discussed current challenges and potential | Glioblastoma (GBM) is an aggressive form of

关键词： disease modeling | drug screening | GBM | GBM-on-a-chip | tumor microenvironment | GBM‐on‐a‐chip

摘要： instruments for on-site or mobile laboratory drug screening | promise for rapid seized drug* screening under controlled* | Increasing seized drug* casework submissions* | and challenges with rapidly triaging seized drug | chemical ionization (TDAPCI) source for seized drug

关键词： Seized drug screening | Controlled substances | Atmospheric pressure chemical ionization | Linear ion trap | Tandem mass spectrometry | Validation

摘要： therapeutic effects. Besides, drug* screening is a high-cost* | throughput drug* screening, respectively. This review* | in drug* delivery and screening and discusses the* | ensuring drug* screening efficiency and efficacy.* | approaches to facilitate drug* development rate. Benefiting*

关键词： Droplet-based 3D bioprinting | Inkjet 3D bioprinting | Personalized medicine | Drug carriers | Drug delivery | Drug screening | Tissue models

摘要： clinical practice and drug* screening. The development of* | models employed in drug* screening typically lack a* | Currently, in vitro skin models are among the | most advanced and frequently utilized tools in | these models often involves the use of skin organoids

关键词： Skin | Skin model | Microbiome | Tissue engineering | Bioprinting

摘要： culture to drug* screening. Furthermore, we explore* | single-cell preparation, organoid culture, and drug | screening with the ultimate goal of ensuring the | Tumor organoids have emerged as an ideal in | vitro model for patient-derived tissues, as they

关键词： tumor organoids | high-throughput technology | individualized medicine | microfluidics | 3D printing | organs-on-chips

摘要： drug screening by racing laboratories but are known | ELISA screening* results are typically produced by non* | degradation. While confirmation of drug* positives can be* | inaccurate ELISA screening* results represents an* | particularly true in the case of rhEPO screening* using*

关键词： ELISA screening | recombinant human erythropoietin | specificity

摘要： personalized in vitro drug* sensitivity screening was* | assess drug* responsiveness. Methods We screened and* | cultured organoids and source tissues. Drug* sensitivity* | , highlighting their value for assessing drug* sensitivity* | Abstract Objective Patient‐derived organoids

关键词： oral squamous cell carcinoma | organoids | precise treatment

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Drug screening is an indispensable procedure | . Microfluidic technology enables drug screening to be | drug screening is presented. The microfluidic | in drug development and pharmaceutical research | . For cell-based drug testing, cells were treated with

关键词： cell-based drug screening assay | concentration gradient generator | centrifugal microfluidics

摘要： past decade, advances in covalent drug discovery have | . Researchers are paying more attention to refining drug | screening methods aiming for high throughput, fast speed | facilitated by significantly reducing screening time and | screening small-molecule compounds in targeted cancer

关键词： Drug screening | small-molecule compounds | targeted cancer therapy | target-based drug screening | phenotype-based drug screening | computer-aided drug discovery

摘要：, providing potential for anti-senescent drug screening. Our | Deep learning-based cell senescence detection | is crucial for accurate quantitative analysis of | senescence assessment. However, senescent cells are small | in size and have little differences in appearance

关键词： Anti-senescence drug screening | Deep learning | Object detection | Swin Transformer

摘要： modeling, drug screening, and personalized medicine | etiology and revolutionize drug development by reducing | and their applications is reported for drug | screening and discussed current challenges and potential | Glioblastoma (GBM) is an aggressive form of

关键词： disease modeling | drug screening | GBM | GBM-on-a-chip | tumor microenvironment | GBM‐on‐a‐chip

摘要： instruments for on-site or mobile laboratory drug screening | promise for rapid seized drug screening under controlled | Increasing seized drug casework submissions | and challenges with rapidly triaging seized drug | chemical ionization (TDAPCI) source for seized drug

关键词： Seized drug screening | Controlled substances | Atmospheric pressure chemical ionization | Linear ion trap | Tandem mass spectrometry | Validation

摘要： therapeutic effects. Besides, drug screening is a high-cost | throughput drug screening, respectively. This review | in drug delivery and screening and discusses the | ensuring drug screening efficiency and efficacy. | approaches to facilitate drug development rate. Benefiting

关键词： Droplet-based 3D bioprinting | Inkjet 3D bioprinting | Personalized medicine | Drug carriers | Drug delivery | Drug screening | Tissue models

摘要： clinical practice and drug screening. The development of | models employed in drug screening typically lack a | Currently, in vitro skin models are among the | most advanced and frequently utilized tools in | these models often involves the use of skin organoids

关键词： Skin | Skin model | Microbiome | Tissue engineering | Bioprinting

摘要： culture to drug screening. Furthermore, we explore | single-cell preparation, organoid culture, and drug | screening with the ultimate goal of ensuring the | Tumor organoids have emerged as an ideal in | vitro model for patient-derived tissues, as they

关键词： tumor organoids | high-throughput technology | individualized medicine | microfluidics | 3D printing | organs-on-chips

摘要： drug screening by racing laboratories but are known | ELISA screening results are typically produced by non | degradation. While confirmation of drug positives can be | inaccurate ELISA screening results represents an | particularly true in the case of rhEPO screening using

关键词： ELISA screening | recombinant human erythropoietin | specificity

摘要： personalized in vitro drug sensitivity screening was | assess drug responsiveness. Methods We screened and | cultured organoids and source tissues. Drug sensitivity | , highlighting their value for assessing drug sensitivity | Abstract Objective Patient‐derived organoids

关键词： oral squamous cell carcinoma | organoids | precise treatment

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：Drug screening is an indispensable procedure | . Microfluidic technology enables drug* screening to be* | drug screening is presented. The microfluidic | in drug* development and pharmaceutical research* | . For cell-based drug* testing, cells were treated with*

摘要：, providing potential for anti-senescent drug* screening. Our* | Deep learning-based cell senescence detection | is crucial for accurate quantitative analysis of | senescence assessment. However, senescent cells are small | in size and have little differences in appearance

摘要： modeling, drug* screening, and personalized medicine* | etiology and revolutionize drug* development by reducing* | and their applications is reported for drug | screening and discussed current challenges and potential | Glioblastoma (GBM) is an aggressive form of

摘要： instruments for on-site or mobile laboratory drug screening | promise for rapid seized drug* screening under controlled* | Increasing seized drug* casework submissions* | and challenges with rapidly triaging seized drug | chemical ionization (TDAPCI) source for seized drug

摘要： therapeutic effects. Besides, drug* screening is a high-cost* | throughput drug* screening, respectively. This review* | in drug* delivery and screening and discusses the* | ensuring drug* screening efficiency and efficacy.* | approaches to facilitate drug* development rate. Benefiting*

摘要： clinical practice and drug* screening. The development of* | models employed in drug* screening typically lack a* | Currently, in vitro skin models are among the | most advanced and frequently utilized tools in | these models often involves the use of skin organoids

摘要： culture to drug* screening. Furthermore, we explore* | single-cell preparation, organoid culture, and drug | screening with the ultimate goal of ensuring the | Tumor organoids have emerged as an ideal in | vitro model for patient-derived tissues, as they

摘要： drug screening by racing laboratories but are known | ELISA screening* results are typically produced by non* | degradation. While confirmation of drug* positives can be* | inaccurate ELISA screening* results represents an* | particularly true in the case of rhEPO screening* using*

摘要： personalized in vitro drug* sensitivity screening was* | assess drug* responsiveness. Methods We screened and* | cultured organoids and source tissues. Drug* sensitivity* | , highlighting their value for assessing drug* sensitivity* | Abstract Objective Patient‐derived organoids