NSTL国家科技图书文献中心

1. STK32C modulates doxorubicin resistance in triple-negative breast cancer cells via glycolysis regulation NSTL国家科技图书文献中心

Xiao, Huawei | Liu, Lei ... - 《Molecular and Cellular Biochemistry》 - 2025,480(1) - 459～471 - 共13页

摘要： doxorubicin resistance in triple-negative breast cancer | little-explored kinase, to impact doxorubicin | unfavorable prognosis in doxorubicin-treated TNBC patients | significantly augmented the sensitivity of doxorubicin | -resistant TNBC cells to doxorubicin. Mechanistically, we

关键词： Triple-negative breast cancer | Doxorubicin resistance | Doxorubicin sensitivity | Glycolysis

2. MALSU1-mediated regulation of mitochondrial function governs proliferation and doxorubicin resistance in triple-negative breast cancer cells NSTL国家科技图书文献中心

Zhuang, Feifei | Huang, Shaoyan ... - 《Molecular and Cellular Biochemistry》 - 2025,480(2) - 1197～1207 - 共11页

摘要： doxorubicin, a widely used chemotherapeutic agent, shows | efficacy in TNBC treatment, acquired resistance* remains a* | and its impact on cell proliferation and doxorubicin | resistance. We observed increased MALSU1 expression in TNBC | knockdown enhanced the sensitivity of doxorubicin

关键词： Triple-negative breast cancer | Doxorubicin resistance | Doxorubicin sensitivity | Mitochondrial respiration

3. Lymphovascular Invasion Is Associated With Doxorubicin Resistance in Breast Cancer NSTL国家科技图书文献中心

Corachea, Allen Joy ... | Ferrer, Regina Joyce...... - 《Laboratory investigation》 - 2025,105(5) - 104115～104115 - 共10页

摘要： drug resistance, which was further confirmed by the | with LVI- tumors. We also observed this resistance* in* | exhibiting lower sensitivity to doxorubicin, implying that | doxorubicin might be less effective for LVI+ breast cancer | Lymphovascular invasion (LVI), the invasion of

关键词： breast cancer | lymphovascular invasion | drug resistance | patient-derived organoids

4. The role of FOXA1 and miR-212-3p in molecular modulation of doxorubicin resistance in liver cancer NSTL国家科技图书文献中心

Elfiky, Ammar | El-Guendy, Nadia ... - 《Medical oncology.》 - 2025,42(5) - Article: 160～Article: 160 - 共14页

摘要： resistance to doxorubicin, we inhibited its expression | essential current treatment for liver cancer. Resistance | to doxorubicin, the chemotherapeutic component of | resistance mechanisms. Upregulation of the Forkhead box A1 | transcription regulator in our model of doxorubicin-resistant

关键词： Liver cancer | FOXA1 | Drug resistance | MicroRNA | Doxorubicin

5. Targeting immune cells in tumor microenvironment in triple negative breast cancer therapy: future perspective to overcome doxorubicin resistance and toxicity NSTL国家科技图书文献中心

Purnomosari, Dewajan... | Nabila, Bilqis Zahra ... - 《Medical oncology.》 - 2025,42(5) - Article: 150～Article: 150 - 共10页

摘要： resistance. The immune cells in the tumor microenvironment | in combination with Doxorubicin* (DOX). Searching* | Triple negative breast cancer (TNBC) has high | recurrence and low survival rates among breast cancer types | . So far, TNBC treatment has been limited to

关键词： Tumor microenvironment | Triple negative breast cancer | Chemotherapy | Doxorubicin | Drug resistance

6. C1GALT1 expression predicts poor survival in osteosarcoma and is crucial for ABCC1 transporter-mediated doxorubicin resistance NSTL国家科技图书文献中心

Liu, Chun-Wei | Huang, Jing-Hui ... - 《Journal of Pathology》 - 2025,265(3) - 289～301 - 共13页

摘要： malignancy with a high propensity for drug resistance* and* | in doxorubicin-selected osteosarcoma cells, where | its suppression significantly promoted doxorubicin | -resistance* phenotype mediated by C1GALT1. C1GALT1-mediated* | Osteosarcoma is an aggressive bone

关键词： C1GALT1 | ABCC1 | doxorubicin | osteosarcoma | chemoresistance | O‐glycosylation | O-glycosylation

7. Morin overcomes doxorubicin resistance in human breast cancer by inducing DNA damage and modulating the LKB1/AMPK/mTORC1 signaling pathway NSTL国家科技图书文献中心

Maharjan, Sushma | Lee, Min-Gu ... - 《BioFactors》 - 2025,51(1) - n/a～n/a - 共19页

摘要：Breast cancer chemoresistance hampers | chemotherapy efficacy; researchers investigate the | pharmacological activities of natural products for potential | solutions. This study aimed to determine the effect of | morin, a bioflavonoid isolated from Maclura pomifera

关键词： cell death | DNA damage | Dox-resistant breast cancer | LKB1/AMPK/mTORC1 pathway | morin | Dox‐resistant breast cancer

8. Hairpin DNA-functionalized gold nanoparticles for diagnostic imaging and overcoming doxorubicin resistance: Enhanced drug loading and cytotoxicity based on thermodynamic guidance NSTL国家科技图书文献中心

Liu, Jie | Wang, Xiangtai ... - 《Journal of Molecular Structure》 - 2025,1337 - 共13页

摘要： for addressing multidrug resistance* (MDR) in* | detect and silence multidrug-resistance-associated | Hairpin DNA-functionalized gold nanoparticles | (hpDNA-AuNPs) have emerged as promising nanocarriers | chemotherapy drug delivery. The interaction between drugs and

关键词： Thermodynamics | Binding affinity | Calorimetry | Gold nanoparticles | Hairpin DNA

9. Curcumin and doxorubicin encapsulated in biocompatible clay-based nanomaterial: A strategy to overcome multidrug resistance NSTL国家科技图书文献中心

Poma, Paola | Massaro, Marina ... - 《Archiv der Pharmazie》 - 2025,358(1) - e2400702～e2400702 - 共11页

摘要：Multidrug resistance* (MDR) due to the* | curcumin and doxorubicin. The efficacy of the co-delivery | of curcumin and doxorubicin* by HNTs-Ht nanomaterial* | causes increased doxorubicin* accumulation by acting as* | efflux transporter on a doxorubicin-resistant breast

关键词： 3D model | clay mineral | curcumin | nanomaterials | P-glycoprotein inhibition

10. Chemotherapy-phototherapy combination drugs co-loaded by a DNA tetrahedron to overcome drug resistance: The influence of different binding properties of doxorubicin and idarubicin and pH response NSTL国家科技图书文献中心

Weng, Tianxin | Liu, Jie ... - 《Dyes and Pigments》 - 2025,235 - 共13页

摘要： resistance (MDR) in tumor cells. The interactions of | -TD and single drug doxorubicin/idarubicin/new | Intelligent DNA nanostructures co-loaded with | chemotherapy-phototherapy (CTPT) combination drugs offer a | promising solution to the challenge of multidrug

摘要： doxorubicin resistance in triple-negative breast cancer | little-explored kinase, to impact doxorubicin | unfavorable prognosis in doxorubicin-treated TNBC patients | significantly augmented the sensitivity of doxorubicin | -resistant TNBC cells to doxorubicin. Mechanistically, we

关键词： Triple-negative breast cancer | Doxorubicin resistance | Doxorubicin sensitivity | Glycolysis

摘要： doxorubicin, a widely used chemotherapeutic agent, shows | efficacy in TNBC treatment, acquired resistance* remains a* | and its impact on cell proliferation and doxorubicin | resistance. We observed increased MALSU1 expression in TNBC | knockdown enhanced the sensitivity of doxorubicin

关键词： Triple-negative breast cancer | Doxorubicin resistance | Doxorubicin sensitivity | Mitochondrial respiration

摘要： drug resistance, which was further confirmed by the | with LVI- tumors. We also observed this resistance* in* | exhibiting lower sensitivity to doxorubicin, implying that | doxorubicin might be less effective for LVI+ breast cancer | Lymphovascular invasion (LVI), the invasion of

关键词： breast cancer | lymphovascular invasion | drug resistance | patient-derived organoids

摘要： resistance to doxorubicin, we inhibited its expression | essential current treatment for liver cancer. Resistance | to doxorubicin, the chemotherapeutic component of | resistance mechanisms. Upregulation of the Forkhead box A1 | transcription regulator in our model of doxorubicin-resistant

关键词： Liver cancer | FOXA1 | Drug resistance | MicroRNA | Doxorubicin

摘要： resistance. The immune cells in the tumor microenvironment | in combination with Doxorubicin* (DOX). Searching* | Triple negative breast cancer (TNBC) has high | recurrence and low survival rates among breast cancer types | . So far, TNBC treatment has been limited to

关键词： Tumor microenvironment | Triple negative breast cancer | Chemotherapy | Doxorubicin | Drug resistance

摘要： malignancy with a high propensity for drug resistance* and* | in doxorubicin-selected osteosarcoma cells, where | its suppression significantly promoted doxorubicin | -resistance* phenotype mediated by C1GALT1. C1GALT1-mediated* | Osteosarcoma is an aggressive bone

关键词： C1GALT1 | ABCC1 | doxorubicin | osteosarcoma | chemoresistance | O‐glycosylation | O-glycosylation

摘要：Breast cancer chemoresistance hampers | chemotherapy efficacy; researchers investigate the | pharmacological activities of natural products for potential | solutions. This study aimed to determine the effect of | morin, a bioflavonoid isolated from Maclura pomifera

关键词： cell death | DNA damage | Dox-resistant breast cancer | LKB1/AMPK/mTORC1 pathway | morin | Dox‐resistant breast cancer

摘要： for addressing multidrug resistance* (MDR) in* | detect and silence multidrug-resistance-associated | Hairpin DNA-functionalized gold nanoparticles | (hpDNA-AuNPs) have emerged as promising nanocarriers | chemotherapy drug delivery. The interaction between drugs and

关键词： Thermodynamics | Binding affinity | Calorimetry | Gold nanoparticles | Hairpin DNA

摘要：Multidrug resistance* (MDR) due to the* | curcumin and doxorubicin. The efficacy of the co-delivery | of curcumin and doxorubicin* by HNTs-Ht nanomaterial* | causes increased doxorubicin* accumulation by acting as* | efflux transporter on a doxorubicin-resistant breast

关键词： 3D model | clay mineral | curcumin | nanomaterials | P-glycoprotein inhibition

摘要： resistance (MDR) in tumor cells. The interactions of | -TD and single drug doxorubicin/idarubicin/new | Intelligent DNA nanostructures co-loaded with | chemotherapy-phototherapy (CTPT) combination drugs offer a | promising solution to the challenge of multidrug

关键词： Spectroscopy | Interaction | Thermodynamic parameters | Combination drugs | pH response

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： doxorubicin resistance in triple-negative breast cancer | little-explored kinase, to impact doxorubicin | unfavorable prognosis in doxorubicin-treated TNBC patients | significantly augmented the sensitivity of doxorubicin | -resistant TNBC cells to doxorubicin. Mechanistically, we

关键词： Triple-negative breast cancer | Doxorubicin resistance | Doxorubicin sensitivity | Glycolysis

摘要： doxorubicin, a widely used chemotherapeutic agent, shows | efficacy in TNBC treatment, acquired resistance remains a | and its impact on cell proliferation and doxorubicin | resistance. We observed increased MALSU1 expression in TNBC | knockdown enhanced the sensitivity of doxorubicin

关键词： Triple-negative breast cancer | Doxorubicin resistance | Doxorubicin sensitivity | Mitochondrial respiration

摘要： drug resistance, which was further confirmed by the | with LVI- tumors. We also observed this resistance in | exhibiting lower sensitivity to doxorubicin, implying that | doxorubicin might be less effective for LVI+ breast cancer | Lymphovascular invasion (LVI), the invasion of

关键词： breast cancer | lymphovascular invasion | drug resistance | patient-derived organoids

关键词： Liver cancer | FOXA1 | Drug resistance | MicroRNA | Doxorubicin

摘要： resistance. The immune cells in the tumor microenvironment | in combination with Doxorubicin (DOX). Searching | Triple negative breast cancer (TNBC) has high | recurrence and low survival rates among breast cancer types | . So far, TNBC treatment has been limited to

关键词： Tumor microenvironment | Triple negative breast cancer | Chemotherapy | Doxorubicin | Drug resistance

摘要： malignancy with a high propensity for drug resistance and | in doxorubicin-selected osteosarcoma cells, where | its suppression significantly promoted doxorubicin | -resistance phenotype mediated by C1GALT1. C1GALT1-mediated | Osteosarcoma is an aggressive bone

关键词： C1GALT1 | ABCC1 | doxorubicin | osteosarcoma | chemoresistance | O‐glycosylation | O-glycosylation

摘要：Breast cancer chemoresistance hampers | chemotherapy efficacy; researchers investigate the | pharmacological activities of natural products for potential | solutions. This study aimed to determine the effect of | morin, a bioflavonoid isolated from Maclura pomifera

关键词： cell death | DNA damage | Dox-resistant breast cancer | LKB1/AMPK/mTORC1 pathway | morin | Dox‐resistant breast cancer

摘要： for addressing multidrug resistance (MDR) in | detect and silence multidrug-resistance-associated | Hairpin DNA-functionalized gold nanoparticles | (hpDNA-AuNPs) have emerged as promising nanocarriers | chemotherapy drug delivery. The interaction between drugs and

关键词： Thermodynamics | Binding affinity | Calorimetry | Gold nanoparticles | Hairpin DNA

摘要：Multidrug resistance (MDR) due to the | curcumin and doxorubicin. The efficacy of the co-delivery | of curcumin and doxorubicin by HNTs-Ht nanomaterial | causes increased doxorubicin accumulation by acting as | efflux transporter on a doxorubicin-resistant breast

关键词： 3D model | clay mineral | curcumin | nanomaterials | P-glycoprotein inhibition

摘要： resistance (MDR) in tumor cells. The interactions of | -TD and single drug doxorubicin/idarubicin/new | Intelligent DNA nanostructures co-loaded with | chemotherapy-phototherapy (CTPT) combination drugs offer a | promising solution to the challenge of multidrug

关键词： Spectroscopy | Interaction | Thermodynamic parameters | Combination drugs | pH response

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： doxorubicin, a widely used chemotherapeutic agent, shows | efficacy in TNBC treatment, acquired resistance* remains a* | and its impact on cell proliferation and doxorubicin | resistance. We observed increased MALSU1 expression in TNBC | knockdown enhanced the sensitivity of doxorubicin

摘要： drug resistance, which was further confirmed by the | with LVI- tumors. We also observed this resistance* in* | exhibiting lower sensitivity to doxorubicin, implying that | doxorubicin might be less effective for LVI+ breast cancer | Lymphovascular invasion (LVI), the invasion of

摘要： resistance. The immune cells in the tumor microenvironment | in combination with Doxorubicin* (DOX). Searching* | Triple negative breast cancer (TNBC) has high | recurrence and low survival rates among breast cancer types | . So far, TNBC treatment has been limited to

摘要： malignancy with a high propensity for drug resistance* and* | in doxorubicin-selected osteosarcoma cells, where | its suppression significantly promoted doxorubicin | -resistance* phenotype mediated by C1GALT1. C1GALT1-mediated* | Osteosarcoma is an aggressive bone

摘要： for addressing multidrug resistance* (MDR) in* | detect and silence multidrug-resistance-associated | Hairpin DNA-functionalized gold nanoparticles | (hpDNA-AuNPs) have emerged as promising nanocarriers | chemotherapy drug delivery. The interaction between drugs and

摘要：Multidrug resistance* (MDR) due to the* | curcumin and doxorubicin. The efficacy of the co-delivery | of curcumin and doxorubicin* by HNTs-Ht nanomaterial* | causes increased doxorubicin* accumulation by acting as* | efflux transporter on a doxorubicin-resistant breast