NSTL国家科技图书文献中心

1. Reduction in presynaptic glutamate release and the prevention of glutamate excitotoxicity by lupeol in rats NSTL国家科技图书文献中心

Lu, Cheng-Wei | Lin, Tzu-Yu ... - 《Neurochemistry International》 - 2025,185 - Article 105951～Article 105951 - 共9页

摘要：, a pentacyclic triterpenoid, affects glutamate | reduced glutamate* release in a manner that could be* | neurodegeneration and downregulated the expression of glutamate | release-related proteins vesicular glutamate* transporter* | the glutamate* levels in the cortices of rats. Our*

关键词： Lupeol | P/Q-type Ca2+channel | Glutamate release inhibition | Glutamate excitotoxicity | Kainic acid | Cortex

2. Channel Engineering of a Glutamate Exporter NSTL国家科技图书文献中心

Zhihua Nie | Pi Liu ... - 《Chembiochem》 - 2025,26(2) - n/a～n/a - 共8页

摘要： involved in glutamate* excretion in most C. glutamicum* | beneficial to the production of glutamate. In this study | the channel entrance for smoother entry of glutamate | negatively charged glutamate* entry. The designed variants* | were found to enhance glutamate* excretion by 2 to 3.3*

关键词： Rational design | Channel engineering | Glutamate exporter | MscCG2

3. The alteration of glutamate involved in the brain of Parkinson's disease patients using glutamate chemical exchange saturation transfer (GluCEST) NSTL国家科技图书文献中心

Liu, Miaomiao | Li, Minglong ... - 《Behavioural Brain Research》 - 2025,483 - Article 115484～Article 115484 - 共7页

摘要：Increased levels of glutamate, a novel | pathogenesis of Parkinson's disease (PD). Although glutamate | variations in glutamate* levels in the striatum and thalamus* | -four healthy controls (HCs). Glutamate* levels were* | . The glutamate* levels in the striatum and thalamus*

关键词： Glutamate chemical exchange saturation | transfer | Parkinson's disease | Glutamate | Striatum | Thalamus

4. Genetic and functional dissection of the glutamate-proline pathway reveals a shortcut for glutamate catabolism in Leishmania NSTL国家科技图书文献中心

Campagnaro, Gustavo ... | Cruz, Angela Kaysel - 《The FEBS journal》 - 2025,292(10) - e70030～e70030 - 共26页

摘要： trypanosomes. Glutamate* is also efficiently used by* | of the glutamate-proline pathway prior to its | , can utilise proline, glutamate* and glutamine as* | proline from glutamate, this pathway has, at best | . In fact, we show that the catabolism of glutamate

关键词： glutamate-proline pathway | Leishmania | mitochondrial metabolism | moonlight activity | proline-glutamate

5. Depression and the Glutamate/GABA-Glutamine Cycle NSTL国家科技图书文献中心

Mamelak, Mortimer - 《Current neuropharmacology.》 - 2025,23(1) - 75～84 - 共10页

摘要： and the reduction in glutamate/GABA-glutamine | , ketamine and ECT, all raise extracellular glutamate* and* | increase glutamate/GABA-glutamine cycling in men and | glutamate. In both animals and man, GHB increases the | level of brain glutamate.

关键词： Depression | stress | glutamate | GABA | glutamine | gammahydroxybutyrate | cholinergic neurotransmission | cerebral metabolic rate

6. Multi-Omic Analysis of Glutamate Excitotoxicity in Primary Neuronal Cultures NSTL国家科技图书文献中心

Jennifer H. Nguyen | Xiaolu Zhang ... - 《Journal of neurochemistry.》 - 2025,169(6) - e70110～e70110 - 共19页

摘要：Glutamate excitotoxicity plays a critical role | glutamate affects neurons in neurological diseases, we | cortical cultures from rat embryos to study glutamate | -induced excitotoxicity. Intermediate doses of glutamate | differentially expressed genes following 250 μM glutamate

关键词： MAPK signaling; glutamate excitotoxicity; kinomics; multiomics; transcriptomics.

7. Glutamate chemical exchange saturation transfer (GluCEST) MRI to evaluate the relationship between demyelination and glutamate content in depressed mice NSTL国家科技图书文献中心

Qi, Kai | Li, Hao ... - 《Behavioural Brain Research》 - 2025,476 - 115247～115247 - 共9页

摘要： consensus on whether glutamate* metabolism changes affect* | . Glutamate* chemical exchange saturation transfer (GluCEST* | that can visualize glutamate* distribution. In this* | at glutamate* levels in mice under chronic* | suggest that altered glutamate* metabolism may be one of*

关键词： Depression | Glutamate | Demyelination | GluCEST | DTI | Luxol Fast Blue | Immunofuorescence

8. Hippocampal-Specific Insulin Resistance Elicits Synaptic Effects on Glutamate Neurotransmission NSTL国家科技图书文献中心

Jennifer M. Erichsen | Jennifer L. Woodruff ... - 《Journal of neurochemistry.》 - 2025,169(6) - e70083～e70083 - 共10页

摘要： glutamate receptors were particularly fascinating, due to | resistance with regard to glutamate* neurotransmission had* | examined hippocampal glutamate* neurochemistry and* | concentrations of glutamate* in the hippocampus, likely a result* | . Additionally, hippocampal glutamate* efflux was significantly*

关键词： glutamate; hippocampal insulin resistance; insulin; insulin resistance; intranasal insulin.

9. Role of Glutamate Excitotoxicity in Glioblastoma Growth and Its Implications in Treatment NSTL国家科技图书文献中心

Moriarty, Colin | Gupta, Natasha ... - 《Cell biology international.》 - 2025,49(5) - 421～434 - 共14页

摘要： astrocytes. Glutamate, a neurotransmitter in the brain | . Excessive glutamate* triggers a pathological process known* | as glutamate* excitotoxicity, leading to neuronal* | glutamate-glutamine homeostasis, releasing excess | glutamate into the extracellular space. This glutamate

关键词： cystine-glutamate antiporter | GLAST | glioblastoma | glutamate | mGlu3R | temozolomide

10. Enzyme-Modified Microelectrodes for Measurement of Glutamate: Characterization and Applications NSTL国家科技图书文献中心

Alyamni, Nadiah | Cook, Clarice ... - 《Electroanalysis》 - 2025,37(3) - n/a～n/a - 共11页

摘要：Glutamate is a critical neurotransmitter in | disorders. Traditional methods of glutamate* detection have* | methods are limited due to glutamate* not being readily* | . This study presents the development of a glutamate | -time detection of glutamate* using fast-scan cyclic*

摘要：, a pentacyclic triterpenoid, affects glutamate | reduced glutamate* release in a manner that could be* | neurodegeneration and downregulated the expression of glutamate | release-related proteins vesicular glutamate* transporter* | the glutamate* levels in the cortices of rats. Our*

关键词： Lupeol | P/Q-type Ca2+channel | Glutamate release inhibition | Glutamate excitotoxicity | Kainic acid | Cortex

摘要： involved in glutamate* excretion in most C. glutamicum* | beneficial to the production of glutamate. In this study | the channel entrance for smoother entry of glutamate | negatively charged glutamate* entry. The designed variants* | were found to enhance glutamate* excretion by 2 to 3.3*

关键词： Rational design | Channel engineering | Glutamate exporter | MscCG2

摘要：Increased levels of glutamate, a novel | pathogenesis of Parkinson's disease (PD). Although glutamate | variations in glutamate* levels in the striatum and thalamus* | -four healthy controls (HCs). Glutamate* levels were* | . The glutamate* levels in the striatum and thalamus*

关键词： Glutamate chemical exchange saturation | transfer | Parkinson's disease | Glutamate | Striatum | Thalamus

摘要： trypanosomes. Glutamate* is also efficiently used by* | of the glutamate-proline pathway prior to its | , can utilise proline, glutamate* and glutamine as* | proline from glutamate, this pathway has, at best | . In fact, we show that the catabolism of glutamate

关键词： glutamate-proline pathway | Leishmania | mitochondrial metabolism | moonlight activity | proline-glutamate

摘要： and the reduction in glutamate/GABA-glutamine | , ketamine and ECT, all raise extracellular glutamate* and* | increase glutamate/GABA-glutamine cycling in men and | glutamate. In both animals and man, GHB increases the | level of brain glutamate.

关键词： Depression | stress | glutamate | GABA | glutamine | gammahydroxybutyrate | cholinergic neurotransmission | cerebral metabolic rate

摘要：Glutamate excitotoxicity plays a critical role | glutamate affects neurons in neurological diseases, we | cortical cultures from rat embryos to study glutamate | -induced excitotoxicity. Intermediate doses of glutamate | differentially expressed genes following 250 μM glutamate

关键词： MAPK signaling; glutamate excitotoxicity; kinomics; multiomics; transcriptomics.

摘要： consensus on whether glutamate* metabolism changes affect* | . Glutamate* chemical exchange saturation transfer (GluCEST* | that can visualize glutamate* distribution. In this* | at glutamate* levels in mice under chronic* | suggest that altered glutamate* metabolism may be one of*

关键词： Depression | Glutamate | Demyelination | GluCEST | DTI | Luxol Fast Blue | Immunofuorescence

关键词： glutamate; hippocampal insulin resistance; insulin; insulin resistance; intranasal insulin.

摘要： astrocytes. Glutamate, a neurotransmitter in the brain | . Excessive glutamate* triggers a pathological process known* | as glutamate* excitotoxicity, leading to neuronal* | glutamate-glutamine homeostasis, releasing excess | glutamate into the extracellular space. This glutamate

关键词： cystine-glutamate antiporter | GLAST | glioblastoma | glutamate | mGlu3R | temozolomide

摘要：Glutamate is a critical neurotransmitter in | disorders. Traditional methods of glutamate* detection have* | methods are limited due to glutamate* not being readily* | . This study presents the development of a glutamate | -time detection of glutamate* using fast-scan cyclic*

关键词： biosensor | carbon‐fiber microelectrode | cyclic voltammetry | enzyme | glutamate | carbon-fiber microelectrode

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：, a pentacyclic triterpenoid, affects glutamate | reduced glutamate release in a manner that could be | neurodegeneration and downregulated the expression of glutamate | release-related proteins vesicular glutamate transporter | the glutamate levels in the cortices of rats. Our

关键词： Lupeol | P/Q-type Ca2+channel | Glutamate release inhibition | Glutamate excitotoxicity | Kainic acid | Cortex

摘要： involved in glutamate excretion in most C. glutamicum | beneficial to the production of glutamate. In this study | the channel entrance for smoother entry of glutamate | negatively charged glutamate entry. The designed variants | were found to enhance glutamate excretion by 2 to 3.3

关键词： Rational design | Channel engineering | Glutamate exporter | MscCG2

摘要：Increased levels of glutamate, a novel | pathogenesis of Parkinson's disease (PD). Although glutamate | variations in glutamate levels in the striatum and thalamus | -four healthy controls (HCs). Glutamate levels were | . The glutamate levels in the striatum and thalamus

关键词： Glutamate chemical exchange saturation | transfer | Parkinson's disease | Glutamate | Striatum | Thalamus

摘要： trypanosomes. Glutamate is also efficiently used by | of the glutamate-proline pathway prior to its | , can utilise proline, glutamate and glutamine as | proline from glutamate, this pathway has, at best | . In fact, we show that the catabolism of glutamate

关键词： glutamate-proline pathway | Leishmania | mitochondrial metabolism | moonlight activity | proline-glutamate

摘要： and the reduction in glutamate/GABA-glutamine | , ketamine and ECT, all raise extracellular glutamate and | increase glutamate/GABA-glutamine cycling in men and | glutamate. In both animals and man, GHB increases the | level of brain glutamate.

关键词： Depression | stress | glutamate | GABA | glutamine | gammahydroxybutyrate | cholinergic neurotransmission | cerebral metabolic rate

摘要：Glutamate excitotoxicity plays a critical role | glutamate affects neurons in neurological diseases, we | cortical cultures from rat embryos to study glutamate | -induced excitotoxicity. Intermediate doses of glutamate | differentially expressed genes following 250 μM glutamate

关键词： MAPK signaling; glutamate excitotoxicity; kinomics; multiomics; transcriptomics.

摘要： consensus on whether glutamate metabolism changes affect | . Glutamate chemical exchange saturation transfer (GluCEST | that can visualize glutamate distribution. In this | at glutamate levels in mice under chronic | suggest that altered glutamate metabolism may be one of

关键词： Depression | Glutamate | Demyelination | GluCEST | DTI | Luxol Fast Blue | Immunofuorescence

关键词： glutamate; hippocampal insulin resistance; insulin; insulin resistance; intranasal insulin.

摘要： astrocytes. Glutamate, a neurotransmitter in the brain | . Excessive glutamate triggers a pathological process known | as glutamate excitotoxicity, leading to neuronal | glutamate-glutamine homeostasis, releasing excess | glutamate into the extracellular space. This glutamate

关键词： cystine-glutamate antiporter | GLAST | glioblastoma | glutamate | mGlu3R | temozolomide

摘要：Glutamate is a critical neurotransmitter in | disorders. Traditional methods of glutamate detection have | methods are limited due to glutamate not being readily | . This study presents the development of a glutamate | -time detection of glutamate using fast-scan cyclic

关键词： biosensor | carbon‐fiber microelectrode | cyclic voltammetry | enzyme | glutamate | carbon-fiber microelectrode

4008-161-200 800-990-8900

国家科技图书文献中心

摘要：, a pentacyclic triterpenoid, affects glutamate | reduced glutamate* release in a manner that could be* | neurodegeneration and downregulated the expression of glutamate | release-related proteins vesicular glutamate* transporter* | the glutamate* levels in the cortices of rats. Our*

摘要： involved in glutamate* excretion in most C. glutamicum* | beneficial to the production of glutamate. In this study | the channel entrance for smoother entry of glutamate | negatively charged glutamate* entry. The designed variants* | were found to enhance glutamate* excretion by 2 to 3.3*

摘要：Increased levels of glutamate, a novel | pathogenesis of Parkinson's disease (PD). Although glutamate | variations in glutamate* levels in the striatum and thalamus* | -four healthy controls (HCs). Glutamate* levels were* | . The glutamate* levels in the striatum and thalamus*

摘要： trypanosomes. Glutamate* is also efficiently used by* | of the glutamate-proline pathway prior to its | , can utilise proline, glutamate* and glutamine as* | proline from glutamate, this pathway has, at best | . In fact, we show that the catabolism of glutamate

摘要： and the reduction in glutamate/GABA-glutamine | , ketamine and ECT, all raise extracellular glutamate* and* | increase glutamate/GABA-glutamine cycling in men and | glutamate. In both animals and man, GHB increases the | level of brain glutamate.

摘要： consensus on whether glutamate* metabolism changes affect* | . Glutamate* chemical exchange saturation transfer (GluCEST* | that can visualize glutamate* distribution. In this* | at glutamate* levels in mice under chronic* | suggest that altered glutamate* metabolism may be one of*

摘要： astrocytes. Glutamate, a neurotransmitter in the brain | . Excessive glutamate* triggers a pathological process known* | as glutamate* excitotoxicity, leading to neuronal* | glutamate-glutamine homeostasis, releasing excess | glutamate into the extracellular space. This glutamate

摘要：Glutamate is a critical neurotransmitter in | disorders. Traditional methods of glutamate* detection have* | methods are limited due to glutamate* not being readily* | . This study presents the development of a glutamate | -time detection of glutamate* using fast-scan cyclic*