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1. Degradation of andrographolide in Andrographis paniculata over 1 year storage NSTL国家科技图书文献中心

Ahammed, Md. Tanvin |  Sultan, Md. Zakir... -  《Phytochemical Analysis》 - 2025,36(1) - 289~295 - 共7页

摘要:Introduction: Andrographolide is a bioactive |  rate of degradation of andrographolide was examined |  concentration of andrographolide after its extraction using |  andrographolide over the storage period. Temperature and |  andrographolide degrades. Conclusion: The results emphasize how
关键词: Andrographis paniculata |  andrographolide |  degradation |  HPLC |  prolonged storage |  Andrographis paniculata

2. Inhibitory effect of andrographolide on the expression of key regulatory genes in Staphylococcus epidermidis biofilm formation NSTL国家科技图书文献中心

Zhang, Kangjian |  Li, Qing... -  《Journal of molecular histology》 - 2025,56(1) - Article: 53~Article: 53 - 共8页

摘要: inhibitory effect of andrographolide on the expression of |  andrographolide on the formation of Staphylococcus epidermidis | - and luxS-related genes of andrographolide on biofilm |  the ability of andrographolide to inhibit biofilm |  of the low- and high-concentration andrographolide
关键词: Andrographolide |  Staphylococcus epidermidis |  Biofilm |  Key regulatory genes |  Inhibition

3. Preparation and characterization of andrographolide nano-cocrystals using hummer acoustic resonance technology NSTL国家科技图书文献中心

Qu, Jianlu |  Wang, Li... -  《International Journal of Pharmaceutics》 - 2025,668 - 124993~124993 - 共14页

摘要:Andrographolide (AG) is a diterpene lactone |  clinical application. An andrographolide-salicylic acid |  with significant anti-inflammatory and antitumor |  activities. However, the poor water solubility limits its |  (AG-SLA) nano-cocrystal delivery system was rapidly
关键词: Andrographolide |  Hummer acoustic resonance |  Nano-cocrystal |  Freeze-drying

4. New Organoruthenium(II) Complexes Containing Andrographolide-Appended Hydrazide Derivatives: Synthesis, Spectral Characterization, Anticancer Evaluation NSTL国家科技图书文献中心

Dhivakar, P. |  Kalaiarasi, G.... -  《Applied Organometallic Chemistry》 - 2025,39(1) - n/a~n/a - 共14页

摘要:A new set of andrographolide-appended |  from the reaction of andrographolide with furan-2 |  ruthenium(II) complexes containing andrographolide-based |  hydrazide derivatives (AFC, AGC, and ATC) were prepared | -carboxylic acid hydrazide (AFC), pyridine-3-carboxylic acid
关键词: andrographolide derivatives |  anticancer studies |  FACS |  Ru(II) arene complexes |  staining assays

5. PCSK5 downregulation promotes the inhibitory effect of andrographolide on glioblastoma through regulating STAT3 NSTL国家科技图书文献中心

Gong, Huiyuan |  Yang, Xiaomin... -  《Molecular and Cellular Biochemistry》 - 2025,480(1) - 521~533 - 共13页

摘要:. Andrographolide is a non-peptide compound with PC inhibition and | Proprotein convertase subtilisin/kexin type 5 |  (PCSK5) is a member of the proprotein convertase (PC | ) family, which processes immature proteins into |  functional proteins and plays an important role in the
关键词: PCSK5 |  Glioblastoma |  EMT |  Andrographolide |  STAT3/MMPs axis

6. Development, Characterization, and Molecular Dynamics Simulation of Andrographolide Nanosuspensions Utilizing Hummer Acoustic Resonance Technology NSTL国家科技图书文献中心

Li,Wang |  Xiaoyang,Zhang... -  《AAPS PharmSciTech》 - 2025,26(5) - Article: 169~Article: 169 - 共16页

摘要:Abstract Andrographolide (AG) is a diterpenoid |  to rapidly develop an andrographolide |  lactone, widely recognized for its potent anti | -inflammatory and immunomodulatory properties. However, AG’s |  clinical applications are significantly limited due to
关键词: Andrographolide |  Hummer acoustic resonance |  Molecular dynamics simulations |  Nanosuspension |  Quality by design

7. Andrographolide mitigates neurotoxicity induced by lipopolysaccharide or amyloid-β through modulation of miR-222-mediated p62 and NF-κBp65 expression NSTL国家科技图书文献中心

Wang, Can |  Liu, Jiayi... -  《European Journal of Pharmacology》 - 2025,988 - 177224~177224 - 共16页

摘要:) patients. Andrographolide (Andro) has been reported to | MicroRNA-222 (miR-222) plays a crucial role in |  neurodegeneration and is up-regulated in Alzheimer's disease (AD |  have anti-inflammatory and neuroprotective effects | , showing potential for treating AD. The relationship
关键词: miR-222 |  Neuroprotective |  Andrographolide

8. Safeguarding Neuronal Integrity: Unveiling Possible Role of NFκB in the Neuroprotective Efficacy of Andrographolide Contrary to Aluminium Chloride-induced Neurotoxicity and Associated Spatial Memory Impairments in Rats NSTL国家科技图书文献中心

Abhitinder Kumar |  Mohit Agrawal... -  《Central nervous system agents in medicinal chemistry》 - 2025,25(2) - 157~168 - 共12页

摘要: andrographolide in the context of aluminum chloride (AlCl 3 |  neurobehavioral outcomes of andrographolide treatment in rats |  andrographolide doses (1, 2, and 3 mg/kg) was grounded in |  tissue. Results: The oral dosing of andrographolide at |  andrographolide. Furthermore, histopathological examinations of
关键词: NFκB |  neurotoxicity |  neuroprotective |  memory deficits |  aluminium chloride |  andrographolide.

9. Synthesis,Structural,Spectroscopic,and Anticancer Studies of 3,19-Furfurylidene-12(S)-thiophenyl-14-deoxy-andrographolide Against 58 Different Cell Lines of Nine Different Cancer Types NSTL国家科技图书文献中心

Nitesh Tamang |  Dipti Ranjan Pati... -  《Chemistry Select》 - 2025,10(3) - e202404092~11 - 共11页

摘要:-andrographolide(12-Ph-S-Fur-ADG)was synthesized and | 3,19-Furfurylidene-12(S)-thiophenyl-14-deoxy |  characterized using the FT-IR,~1H NMR,and ~(13)C NMR,DEPT-45 | ,DEPT-90,DEPT-135,and 2D-NMR(HOMO-COSY and HSQC)and |  HRMS spectroscopy.A single product was obtained when
关键词: Andrographolide |  Anticancer |  NCI |  XRD

10. Optimizing Andrographolide from Sambiloto Leaves (Andrographis paniculata) Using Cyclodextrin Metal-Organic Frameworks for Targeted Pulmonary Delivery via a Metered Dose Inhaler: A Proof-Of-Concept Study NSTL国家科技图书文献中心

Syauqi, Muhammad Amm... |  Burhanuddin, Andi Za...... -  《Molecular pharmaceutics》 - 2025,22(3) - 1280~1292 - 共13页

摘要: primary compound of this plant, andrographolide (AG | Andrographis paniculata is recognized for its |  numerous applications in the pharmaceutical industry. The | ), has demonstrated potent antibacterial properties | , including against K. pneumoniae. However, its poor
关键词: andrographolide |  cyclodextrin |  metal-organicframeworks |  metered dose inhaler |  pneumonia
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