NSTL国家科技图书文献中心

1. Longitudinal population analysis of Plasmodium falciparum apical membrane antigen-1 in Indian field isolates NSTL国家科技图书文献中心

Geetika Narang | Joseph Hawadak ... - 《Acta tropica.》 - 2025,266 - Article 107630～Article 107630 - 共11页

摘要： Plasmodium falciparum apical* membrane *antigen-1 (Pfama-1 | antigen requires information about existing genetic | diversity of gene in circulation. Genotyping of Pfama-1 | explore the longitudinal variation in Pfama-1 in Indian | observed indicating that Indian Pfama-1 is under

关键词： Apical membrane antigen-1; India; Natural selection; Plasmodium falciparum; Population genetics

2. Oral DNA Vaccine Utilizing the Yeast Cell Wall for Dectin-1 Receptor-Mediated Enhancement of Mucosal Immunity NSTL国家科技图书文献中心

Liu, Yingqi | Meng, Fan ... - 《Molecular pharmaceutics》 - 2025,22(3) - 1241～1252 - 共12页

摘要： by the apical* membrane receptor, dectin-1, which* | antigen-presenting cells via receptor dectin-1-mediated | Mucosal vaccines can generate localized | mucosal immunity, effectively preventing initial | pathogen infection and providing more effective

关键词： protamine | yeast cell wall | dectin-1 | oral vaccines | mucosal immunity

3. Genetic diversity and natural selection of apical membrane antigen-1 (ama-1) in Cameroonian Plasmodium falciparum isolates NSTL国家科技图书文献中心

Hawadak, Joseph | Foko, Loick Pradel K...... - 《Gene: An International Journal Focusing on Gene Cloning and Gene Structure and Function》 - 2024,894 - 147956～147956 - 共6页

摘要： diversity in global Plasmodium falciparum apical membrane | antigen-1 (PfAMA-1) is a major impediment to designing | of the Pfama-1 gene in P. falciparum isolates from | Pfama-1 gene was amplified for polymorphism profiling | data on existing Pfama-1 gene polymorphisms in

关键词： Plasmodium falciparum | Apical membrane antigen-1 | Vaccine | Population genetics | Evolution | Natural selection | MALARIA VACCINE CANDIDATE | POPULATION-STRUCTURE | INVASION | ANTIBODY...

4. Immunogenic and diagnostic potential of recombinant apical membrane antigen-1 from Plasmodium malariae NSTL国家科技图书文献中心

Li, Moyan | Liu, Tingting ... - 《Diagnostic microbiology and infectious disease》 - 2024,110(3) - 116480～116480 - 共6页

摘要：The apical* membrane *antigen-1 (AMA-1) is a | strategies. While the immunogenicity of AMA-1 has been | Plasmodium malariae. In this study, recombinant PmAMA-1 was | -1 emulsified in Freund's adjuvant resulted in | PmAMA-1 on P. malariae. These results suggest that

关键词： Plasmodium malariae | AMA-1 | Immunogenicity | IgG subclasses | Cytokines | ERYTHROCYTE INVASION | NAIVE ADULTS | DOUBLE-BLIND | VACCINE | ANTIBODIES...

5. A Diversity Covering (DiCo) Plasmodium vivax apical membrane antigen-1 vaccine adjuvanted with RFASE/RSL10 yields high levels of growth-inhibitory antibodies NSTL国家科技图书文献中心

Faber, Bart W. | Yeoh, Lee M.... - 《Vaccine》 - 2024,42(7) - 1785～1792 - 共8页

摘要：Plasmodium vivax malaria is increasingly | recognized as a major global health problem and the socio | -economic impact of P.vivax-induced burden is huge | . Vaccine development against P. vivax malaria has been | hampered by the lack of an in vitro culture system and

关键词： PLASMODIUM-VIVAX | IMMUNOGENICITY TRIAL | IMMUNE-RESPONSES | PICHIA-PASTORIS | FALCIPARUM | IMMUNIZATION | CANDIDATE | SAFETY | EXPRESSION | MONKEY

6. Identification and molecular characterization of a novel Babesia orientalis rhoptry neck protein 4 (BoRON4) NSTL国家科技图书文献中心

Li, Fangjie | Guo, Jiaying ... - 《Parasitology Research》 - 2024,123(8) - Article: 310～Article: 310 - 共6页

摘要： apical membrane antigen 1 (AMA1). However, the | -6p-1 vector for fusion expression. We successfully | promising candidate antigen* for distinguishing water* | diagnostic antigen* for babesiosis in water buffalo* | Babesia orientalis, a protozoan parasite

关键词： Babesia orientalis | Rhoptry neck protein 4 | Babesiosis | Immunogenicity | MEMBRANE ANTIGEN 1 | IMMUNE EVASION | MALARIA | INVASION | VACCINE

7. Extended Conformational Selection in the Antigen-Antibody Interaction of the PfAMA1 Protein NSTL国家科技图书文献中心

da Silva, Pamella Cr... | Martinez, Leandro - 《The journal of physical chemistry, B. Condensed matter, materials, surfaces, interfaces & biophysical》 - 2024,128(35) - 8400～8408 - 共9页

摘要：Plasmodium falciparum apical membrane antigen | 1 (PfAMA1) is a surface protein found in two | intrinsically disordered regions on the mechanism of antigen | stages of the malaria life cycle. This is a protein | involved in a reorientation movement of the parasite so

关键词： EXCHANGE MOLECULAR-DYNAMICS | INDUCED FIT | DOMAIN-III | BINDING | PROTOCOL

8. Prostate‐specific membrane antigen (PSMA) glycoforms in prostate cancer patients seminal plasma NSTL国家科技图书文献中心

Stephen Mackay | Ian O. Oduor ... - 《The Prostate》 - 2024,84(5) - 479～490 - 共12页

摘要： membrane antigen (PSMA) is a US?Food and Drug | Groups 1 and 2 PCa patients. Intact glycopeptides were | the plasma membrane. The glycoforms at ASN‐459, ASN | basal domain facing the plasma membrane* in cells, are* | the interdomain region adjacent to the apical* domain*

关键词： glutamate carboxypeptidase | N‐linked glycosylation | prostate cancer | PSMA | seminal plasma | site‐specific glycoform

9. A retrospective analysis of P. falciparum drug resistance markers detects an early (2016/17) high prevalence of the k13 C469Y mutation in asymptomatic infections in Northern Uganda NSTL国家科技图书文献中心

Ogwang, Rodney | Osoti, Victor ... - 《Antimicrobial agents and chemotherapy.》 - 2024,68(9) - e0157623～e0157623 - 共6页

摘要：), dihydrofolate reductase (Pfdhfr), and apical membrane antigen | synthase (Pfdhps), multidrug resistance-1 (Pfmdr1 | The emergence of drug-resistant Plasmodium | falciparum parasites in sub-Saharan Africa will | substantially challenge malaria control. Here, we evaluated

关键词： Plasmodium falciparum | molecular surveillance | amplicon sequencing | artemisinin resistance | PLASMODIUM-FALCIPARUM | ARTEMISININ RESISTANCE | MALARIA PARASITES

10. The direct binding of Plasmodium vivax AMA1 to erythrocytes defines a RON2-independent invasion pathway NSTL国家科技图书文献中心

Lee S.-K. | Low L.M.... - 《Proceedings of the National Academy of Sciences of the United States of America.》 - 2023,120(1) - e2210283120～e2210283120 - 共6页

摘要： to express Plasmodium vivax apical membrane antigen | 1 (PvAMA1) protein in place of PfAMA1 to study | PvAMA1 domains 1 and 2 (rPvAMA1) bound to reticulocytes | We used a transgenic parasite in which | Plasmodium falciparum parasites were genetically modified

摘要： Plasmodium falciparum apical* membrane *antigen-1 (Pfama-1 | antigen requires information about existing genetic | diversity of gene in circulation. Genotyping of Pfama-1 | explore the longitudinal variation in Pfama-1 in Indian | observed indicating that Indian Pfama-1 is under

关键词： Apical membrane antigen-1; India; Natural selection; Plasmodium falciparum; Population genetics

摘要： by the apical* membrane receptor, dectin-1, which* | antigen-presenting cells via receptor dectin-1-mediated | Mucosal vaccines can generate localized | mucosal immunity, effectively preventing initial | pathogen infection and providing more effective

关键词： protamine | yeast cell wall | dectin-1 | oral vaccines | mucosal immunity

摘要： diversity in global Plasmodium falciparum apical membrane | antigen-1 (PfAMA-1) is a major impediment to designing | of the Pfama-1 gene in P. falciparum isolates from | Pfama-1 gene was amplified for polymorphism profiling | data on existing Pfama-1 gene polymorphisms in

关键词： Plasmodium falciparum | Apical membrane antigen-1 | Vaccine | Population genetics | Evolution | Natural selection | MALARIA VACCINE CANDIDATE | POPULATION-STRUCTURE | INVASION | ANTIBODY...

摘要：The apical* membrane *antigen-1 (AMA-1) is a | strategies. While the immunogenicity of AMA-1 has been | Plasmodium malariae. In this study, recombinant PmAMA-1 was | -1 emulsified in Freund's adjuvant resulted in | PmAMA-1 on P. malariae. These results suggest that

关键词： Plasmodium malariae | AMA-1 | Immunogenicity | IgG subclasses | Cytokines | ERYTHROCYTE INVASION | NAIVE ADULTS | DOUBLE-BLIND | VACCINE | ANTIBODIES...

摘要：Plasmodium vivax malaria is increasingly | recognized as a major global health problem and the socio | -economic impact of P.vivax-induced burden is huge | . Vaccine development against P. vivax malaria has been | hampered by the lack of an in vitro culture system and

关键词： PLASMODIUM-VIVAX | IMMUNOGENICITY TRIAL | IMMUNE-RESPONSES | PICHIA-PASTORIS | FALCIPARUM | IMMUNIZATION | CANDIDATE | SAFETY | EXPRESSION | MONKEY

摘要： apical membrane antigen 1 (AMA1). However, the | -6p-1 vector for fusion expression. We successfully | promising candidate antigen* for distinguishing water* | diagnostic antigen* for babesiosis in water buffalo* | Babesia orientalis, a protozoan parasite

关键词： Babesia orientalis | Rhoptry neck protein 4 | Babesiosis | Immunogenicity | MEMBRANE ANTIGEN 1 | IMMUNE EVASION | MALARIA | INVASION | VACCINE

摘要：Plasmodium falciparum apical membrane antigen | 1 (PfAMA1) is a surface protein found in two | intrinsically disordered regions on the mechanism of antigen | stages of the malaria life cycle. This is a protein | involved in a reorientation movement of the parasite so

关键词： EXCHANGE MOLECULAR-DYNAMICS | INDUCED FIT | DOMAIN-III | BINDING | PROTOCOL

摘要： membrane antigen (PSMA) is a US?Food and Drug | Groups 1 and 2 PCa patients. Intact glycopeptides were | the plasma membrane. The glycoforms at ASN‐459, ASN | basal domain facing the plasma membrane* in cells, are* | the interdomain region adjacent to the apical* domain*

关键词： glutamate carboxypeptidase | N‐linked glycosylation | prostate cancer | PSMA | seminal plasma | site‐specific glycoform

摘要：), dihydrofolate reductase (Pfdhfr), and apical membrane antigen | synthase (Pfdhps), multidrug resistance-1 (Pfmdr1 | The emergence of drug-resistant Plasmodium | falciparum parasites in sub-Saharan Africa will | substantially challenge malaria control. Here, we evaluated

关键词： Plasmodium falciparum | molecular surveillance | amplicon sequencing | artemisinin resistance | PLASMODIUM-FALCIPARUM | ARTEMISININ RESISTANCE | MALARIA PARASITES

摘要： to express Plasmodium vivax apical membrane antigen | 1 (PvAMA1) protein in place of PfAMA1 to study | PvAMA1 domains 1 and 2 (rPvAMA1) bound to reticulocytes | We used a transgenic parasite in which | Plasmodium falciparum parasites were genetically modified

关键词： apical membrane antigen 1 | Plasmodium vivax | transgenic parasites

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： Plasmodium falciparum apical membrane antigen-1 (Pfama-1 | antigen requires information about existing genetic | diversity of gene in circulation. Genotyping of Pfama-1 | explore the longitudinal variation in Pfama-1 in Indian | observed indicating that Indian Pfama-1 is under

关键词： Apical membrane antigen-1; India; Natural selection; Plasmodium falciparum; Population genetics

摘要： by the apical membrane receptor, dectin-1, which | antigen-presenting cells via receptor dectin-1-mediated | Mucosal vaccines can generate localized | mucosal immunity, effectively preventing initial | pathogen infection and providing more effective

关键词： protamine | yeast cell wall | dectin-1 | oral vaccines | mucosal immunity

摘要： diversity in global Plasmodium falciparum apical membrane | antigen-1 (PfAMA-1) is a major impediment to designing | of the Pfama-1 gene in P. falciparum isolates from | Pfama-1 gene was amplified for polymorphism profiling | data on existing Pfama-1 gene polymorphisms in

关键词： Plasmodium falciparum | Apical membrane antigen-1 | Vaccine | Population genetics | Evolution | Natural selection | MALARIA VACCINE CANDIDATE | POPULATION-STRUCTURE | INVASION | ANTIBODY...

摘要：The apical membrane antigen-1 (AMA-1) is a | strategies. While the immunogenicity of AMA-1 has been | Plasmodium malariae. In this study, recombinant PmAMA-1 was | -1 emulsified in Freund's adjuvant resulted in | PmAMA-1 on P. malariae. These results suggest that

关键词： Plasmodium malariae | AMA-1 | Immunogenicity | IgG subclasses | Cytokines | ERYTHROCYTE INVASION | NAIVE ADULTS | DOUBLE-BLIND | VACCINE | ANTIBODIES...

摘要：Plasmodium vivax malaria is increasingly | recognized as a major global health problem and the socio | -economic impact of P.vivax-induced burden is huge | . Vaccine development against P. vivax malaria has been | hampered by the lack of an in vitro culture system and

关键词： PLASMODIUM-VIVAX | IMMUNOGENICITY TRIAL | IMMUNE-RESPONSES | PICHIA-PASTORIS | FALCIPARUM | IMMUNIZATION | CANDIDATE | SAFETY | EXPRESSION | MONKEY

摘要： apical membrane antigen 1 (AMA1). However, the | -6p-1 vector for fusion expression. We successfully | promising candidate antigen for distinguishing water | diagnostic antigen for babesiosis in water buffalo | Babesia orientalis, a protozoan parasite

关键词： Babesia orientalis | Rhoptry neck protein 4 | Babesiosis | Immunogenicity | MEMBRANE ANTIGEN 1 | IMMUNE EVASION | MALARIA | INVASION | VACCINE

摘要：Plasmodium falciparum apical membrane antigen | 1 (PfAMA1) is a surface protein found in two | intrinsically disordered regions on the mechanism of antigen | stages of the malaria life cycle. This is a protein | involved in a reorientation movement of the parasite so

关键词： EXCHANGE MOLECULAR-DYNAMICS | INDUCED FIT | DOMAIN-III | BINDING | PROTOCOL

摘要： membrane antigen (PSMA) is a US?Food and Drug | Groups 1 and 2 PCa patients. Intact glycopeptides were | the plasma membrane. The glycoforms at ASN‐459, ASN | basal domain facing the plasma membrane in cells, are | the interdomain region adjacent to the apical domain

关键词： glutamate carboxypeptidase | N‐linked glycosylation | prostate cancer | PSMA | seminal plasma | site‐specific glycoform

摘要：), dihydrofolate reductase (Pfdhfr), and apical membrane antigen | synthase (Pfdhps), multidrug resistance-1 (Pfmdr1 | The emergence of drug-resistant Plasmodium | falciparum parasites in sub-Saharan Africa will | substantially challenge malaria control. Here, we evaluated

关键词： Plasmodium falciparum | molecular surveillance | amplicon sequencing | artemisinin resistance | PLASMODIUM-FALCIPARUM | ARTEMISININ RESISTANCE | MALARIA PARASITES

摘要： to express Plasmodium vivax apical membrane antigen | 1 (PvAMA1) protein in place of PfAMA1 to study | PvAMA1 domains 1 and 2 (rPvAMA1) bound to reticulocytes | We used a transgenic parasite in which | Plasmodium falciparum parasites were genetically modified

关键词： apical membrane antigen 1 | Plasmodium vivax | transgenic parasites

4008-161-200 800-990-8900

国家科技图书文献中心

摘要： Plasmodium falciparum apical* membrane *antigen-1 (Pfama-1 | antigen requires information about existing genetic | diversity of gene in circulation. Genotyping of Pfama-1 | explore the longitudinal variation in Pfama-1 in Indian | observed indicating that Indian Pfama-1 is under

摘要： by the apical* membrane receptor, dectin-1, which* | antigen-presenting cells via receptor dectin-1-mediated | Mucosal vaccines can generate localized | mucosal immunity, effectively preventing initial | pathogen infection and providing more effective

摘要：The apical* membrane *antigen-1 (AMA-1) is a | strategies. While the immunogenicity of AMA-1 has been | Plasmodium malariae. In this study, recombinant PmAMA-1 was | -1 emulsified in Freund's adjuvant resulted in | PmAMA-1 on P. malariae. These results suggest that

摘要： apical membrane antigen 1 (AMA1). However, the | -6p-1 vector for fusion expression. We successfully | promising candidate antigen* for distinguishing water* | diagnostic antigen* for babesiosis in water buffalo* | Babesia orientalis, a protozoan parasite

摘要： membrane antigen (PSMA) is a US?Food and Drug | Groups 1 and 2 PCa patients. Intact glycopeptides were | the plasma membrane. The glycoforms at ASN‐459, ASN | basal domain facing the plasma membrane* in cells, are* | the interdomain region adjacent to the apical* domain*