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1. Metabolic complexities and heterogeneity in quorum sensing signaling molecules in bacteria isolated from black band disease in a Caribbean coral NSTL国家科技图书文献中心

Ripe-Jaime, Laura |  Diaz, Erika... -  《Research in Microbiology》 - 2025,176(1/2) - 104248~104248 - 共15页

摘要:Coral diseases contribute to the worldwide |  loss of coral reefs, with the Black Band Disease (BBD | ) being a prominent example. BBD is an infectious |  condition with lesions with a pigmented mat composed of |  cyanobacteria, sulphate-reducing, sulphide-oxidizing, and
关键词: Bacterial isolates |  Orbicella faveolata |  Black band disease |  Coral disease |  Quorum sensing

2. Disseminated fusariosis after allogenic hematopoietic stem cell transplantation: case report NSTL国家科技图书文献中心

Gantner, A. |  Hagemann, J. B.... -  《Infection》 - 2025,53(2) - 727~731 - 共5页

摘要:In allogenic stem cell recipients, invasive |  fungal disease is a common yet dreaded complication |  with high mortality. Among these, fusariosis is |  especially complex to treat due to high intrinsic |  resistance and few antimycotic options, requiring close
关键词: Allogenic hematopoietic stem cell transplantation |  Fusariosis |  Fusarium |  Fungal infection

3. In Vitro Influence of Specific Bacteroidales Strains on Gut and Liver Health Related to Metabolic Dysfunction-Associated Fatty Liver Disease NSTL国家科技图书文献中心

Garcia-Morena, Diego |  Fernandez-Cantos, Ma...... -  《Probiotics and Antimicrobial Proteins》 - 2025,17(3) - 1498~1512 - 共15页

摘要:Metabolic dysfunction-associated fatty liver |  disease (MAFLD) has become a major health risk and a |  serious worldwide issue. MAFLD typically arises from |  aberrant lipid metabolism, insulin resistance, oxidative |  stress, and inflammation. However, subjacent causes are
关键词: MAFLD |  Microbiota |  Bacteroidales |  Antimicrobials |  Fatty liver |  Probiotics

4. Controlling Substrate- and Stereospecificity of Condensation Domains in Nonribosomal Peptide Synthetases NSTL国家科技图书文献中心

Peng, Huiyun |  Schmiederer, Julian... -  《ACS Chemical Biology》 - 2024,19(3) - 599~606 - 共8页 - 被引量:1

摘要:Nonribosomal peptide synthetases (NRPSs) are |  sophisticated molecular machines that biosynthesize peptide |  drugs. In attempts to generate new bioactive compounds | , some parts of NRPSs have been successfully |  manipulated, but especially the influence of condensation (C
关键词: AMINO-ACID |  BIOSYNTHESIS OPERON |  SELECTIVITY |  PROBES

5. Modeling of intravenous caspofungin administration using an intestine-on-chip reveals altered Candida albicans microcolonies and pathogenicity NSTL国家科技图书文献中心

Kaden, Tim |  Alonso-Roman, Raquel... -  《Biomaterials》 - 2024,307 - ARTN 122525~ - 共18页

摘要:Candida albicans is a commensal yeast of the |  human intestinal microbiota that, under predisposing |  conditions, can become pathogenic and cause life | -threatening systemic infections (candidiasis). Fungal-host |  interactions during candidiasis are commonly studied using
关键词: Organ -on -chip |  Image-based analysis |  Infection model |  Candidiasis |  Antifungals |  GASTROINTESTINAL COLONIZATION |  INVASIVE CANDIDIASIS |  MUCOSAL |  MICE |  SUSCEPTIBILITIES...

6. Bacteria modulate microalgal aging physiology through the induction of extracellular vesicle production to remove harmful metabolites NSTL国家科技图书文献中心

Deng, Yun |  Yu, Ruyi... -  《Nature Microbiology》 - 2024,9(9) - 共26页

摘要:The bloom and bust patterns of microalgae in |  aquatic systems contribute massively to global |  biogeochemical cycles. The decline of algal blooms is mainly |  caused by nutrient limitation resulting in cell death | , the arrest of cell division and the aging of
关键词: GROWTH-PHASE |  DIATOM |  SILICATE |  COMMUNICATION |  BLOOM |  CYCLE |  WAKE

7. Analysis of the Valgamicin Biosynthetic Pathway Reveals a General Mechanism for Cyclopropanol Formation across Diverse Natural Product Scaffolds NSTL国家科技图书文献中心

Little, Rory F. |  Trottmann, Felix... -  《ACS Chemical Biology》 - 2024,19(3) - 660~668 - 共9页 - 被引量:2

摘要:Cyclopropanol rings are highly reactive and |  may function as molecular "warheads" that affect |  natural product bioactivity. Yet, knowledge on their |  biosynthesis is limited. Using gene cluster analyses, isotope |  labeling, and in vitro enzyme assays, we shed first light
关键词: STEREOCONTROLLED SYNTHESIS |  BURKHOLDERIA-PSEUDOMALLEI |  POLYKETIDE |  ACID |  DISCOVERY |  SEQUENCE |  STRAIN

8. Plant and algal lipidomes: Analysis, composition, and their societal significance NSTL国家科技图书文献中心

Jouhet, Juliette |  Alves, Eliana... -  《Progress in Lipid Research》 - 2024,96 - 101290~101290 - 共30页

摘要:Plants and algae play a crucial role in the |  earth's ecosystems. Through photosynthesis they convert |  light energy into chemical energy, capture CO2 and |  produce oxygen and energy-rich organic compounds | . Photosynthetic organisms are primary producers and synthesize
关键词: Lipids |  Fatty acids |  Lipidomics |  Plants |  Macroalgae |  Microalgae |  Seaweeds

9. Biomimetic engineering of nonribosomal peptide synthesis NSTL国家科技图书文献中心

Zhang, Kexin |  Kries, Hajo -  《Biochemical Society transactions.》 - 2023,51(4) - 1521~1532 - 共12页

摘要:Nonribosomal peptides (NRPs) have gained |  attention due to their diverse biological activ-ities and |  potential applications in medicine and agriculture. The |  natural diversity of NRPs is a result of evolutionary |  processes that have occurred over millions of years
关键词: NATURAL-PRODUCTS |  ADENYLATION DOMAINS |  DIRECTED EVOLUTION |  STRUCTURAL BASIS |  CONFERRING CODE |  BIOSYNTHESIS |  SYNTHETASES |  MODULE |  SPECIFICITY |  ENZYMES

10. Discovery and Biosynthesis of the Cytotoxic Polyene Terpenomycin in Human Pathogenic Nocardia NSTL国家科技图书文献中心

Herisse, Marion |  Ishida, Keishi... -  《ACS Chemical Biology》 - 2023,18(8) - 1872~1879 - 共8页

摘要:Nocardia are opportunistic humanpathogens that |  can cause a range of debilitating and difficult |  totreat infections of the lungs, brain, skin, and soft |  tissues. Despitetheir close relationship to the well | -known secondary metabolite-producinggenus
关键词: ACYL CARRIER PROTEIN |  GENE-CLUSTER |  POLYKETIDE SYNTHASE |  ANTIFUNGAL |  INHIBITORS |  SUBSTRATE |  MACROLIDE |  BAFILOMYCINS |  ANSAMITOCIN |  EXPRESSION
检索条件机构:Leibniz Inst Nat Prod Res & Infect Biol

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