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1. Time-Dependent Transcriptional Dynamics of Contextual Fear Memory Retrieval Reveals the Function of Dipeptidyl Peptidase 9 in Reconsolidation

Guo, Wen-Ting |  Li, Wen-Xing... -  《neuroscience bulletin》 - 2025,41(1) - 16~32 - 共17页

摘要:Numerous studies on the formation and |  consolidation of memory have shown that memory processes are |  characterized by phase-dependent and dynamic regulation | . Memory retrieval, as the only representation of memory |  content and an active form of memory processing that
关键词: Transcriptome analysis |  Temporal gene expression |  Fear memory retrieval |  Reconsolidation |  DPP9 |  DOMAIN-CONTAINING PROTEIN |  LONG-TERM-MEMORY |  SYNAPTIC PLASTICITY |  MOLECULAR REQUIREMENTS |  AMPA RECEPTORS...

2. The Role of Neuroinflammation and Network Anomalies in Drug-Resistant Epilepsy

Shi, Jianwei |  Xie, Jing... -  《neuroscience bulletin》 - 2025, - 共25页

摘要:Epilepsy affects over 50 million people |  worldwide. Drug-resistant epilepsy (DRE) accounts for up |  to a third of these cases, and neuro-inflammation |  is thought to play a role in such cases. Despite |  being a long-debated issue in the field of DRE, the
关键词: Neuroglia |  Neuro-immune interaction |  Brain network |  Chronicity |  Epilepsy |  TEMPORAL-LOBE EPILEPSY |  DEEP BRAIN-STIMULATION |  REACTIVE ASTROCYTES |  PARKINSONS-DISEASE |  WHITE-MATTER...

3. Endothelial Cell Integrin α6 Regulates Vascular Remodeling Through the PI3K/Akt-eNOS-VEGFA Axis After Stroke

Wang, Bing-Qiao |  Duan, Yang-Ying... -  《neuroscience bulletin》 - 2025, - 共15页

摘要:The angiogenic response is essential for the |  repair of ischemic brain tissue. Integrin alpha 6 |  (Itga6) expression has been shown to increase under |  hypoxic conditions and is expressed exclusively in |  vascular structures; however, its role in post-ischemic
关键词: Integrin alpha 6 |  Ischemia |  Angiogenesis |  INCREASED EXPRESSION |  ISCHEMIC-STROKE |  ANGIOGENESIS |  PROLIFERATION |  DISRUPTION |  INJURY |  MICE

4. Transcranial temporal interference stimulation precisely targets deep brain regions to regulate eye movements

Wang, Mo |  Song, Sixian... -  《neuroscience bulletin》 - 2025, - 共13页

摘要:Transcranial temporal interference stimulation |  (tTIS) is a novel non-invasive neuromodulation |  technique with the potential to precisely target deep |  brain structures. This study explores the neural and |  behavioral effects of tTIS on the superior colliculus (SC
关键词: Temporal interference stimulation |  Superior colliculus |  Tissue phantom |  Finite element method |  Transcranial electrical stimulation |  Eye movement

5. A Personalized Predictor of Motor Imagery Ability Based on Multi-frequency EEG Features

Li, Mengfan |  Zhao, Qi... -  《neuroscience bulletin》 - 2025, - 共15页

摘要:A brain-computer interface (BCI) based on |  motor imagery (MI) provides additional control |  pathways by decoding the intentions of the brain. MI |  ability has great intra-individual variability, and the |  majority of MI-BCI systems are unable to adapt to this
关键词: EEG |  Brain computer interface |  Motor imagery |  Personalized predictor |  BRAIN-COMPUTER-INTERFACE |  BCI PERFORMANCE |  CLASSIFICATION |  PATTERNS |  ALPHA

6. Histopathological Insights into Demyelination and Remyelination After Spinal Cord Injury in Non-human Primates

Liu, Junhao |  Huang, Zucheng... -  《neuroscience bulletin》 - 2025, - 共19页

摘要:Demyelination and remyelination play key roles |  in spinal cord injury (SCI), affecting the recovery |  of motor and sensory functions. Research in rodent |  models is extensive, but the study of these processes |  in non-human primates is limited. Therefore, our
关键词: Demyelination |  Remyelination |  Spinal cord injury |  Histological analysis |  Non-human primate |  SCHWANN-CELLS |  RECOVERY |  RAT |  OLIGODENDROCYTES |  TRANSPLANTATION...

7. Computational Modeling of the Prefrontal-Cingulate Cortex to Investigate the Role of Coupling Relationships for Balancing Emotion and Cognition

Wei, Jinzhao |  Li, Licong... -  《neuroscience bulletin》 - 2025,41(1) - 33~45 - 共13页

摘要:Within the prefrontal-cingulate cortex | , abnormalities in coupling between neuronal networks can |  disturb the emotion-cognition interactions, contributing |  to the development of mental disorders such as |  depression. Despite this understanding, the neural circuit
关键词: Prefrontal-cingulate cortex |  Computational modeling |  Coupling relationships |  Depression |  Emotion and cognition |  DEEP BRAIN-STIMULATION |  LATE-LIFE DEPRESSION |  FUNCTIONAL CONNECTIVITY |  RESTING STATE |  NETWORKS...

8. The Supplementary Motor Area as a Flexible Hub Mediating Behavioral and Neuroplastic Changes in Motor Sequence Learning: A TMS and TMS-EEG Study

Chen, Jing |  Fan, Yanzi... -  《neuroscience bulletin》 - 2025, - 共16页

摘要:Attempts have been made to modulate motor |  sequence learning (MSL) through repetitive transcranial |  magnetic stimulation, targeting different sites within |  the sensorimotor network. However, the target with |  the optimum modulatory effect on neural plasticity
关键词: Motor sequence learning |  Intermittent theta burst stimulation |  Concurrent transcranial magnetic stimulation and electroencephalogram |  Neuroplasticity |  Functional connectivity |  THETA-BURST STIMULATION |  TRANSCRANIAL MAGNETIC STIMULATION |  REPETITIVE TMS |  CORTICOSPINAL EXCITABILITY |  CORTICAL EXCITABILITY...

9. A Novel Functional Method of Protector Screening for Zebrafish Lateral Line Hair Cells via the Acoustic Escape Response

Zheng, Ling |  Shen, Qiaosen... -  《neuroscience bulletin》 - 2025, - 共16页

摘要:Zebrafish larvae are useful for identifying |  chemicals against lateral line (LL) hair cell (HC) damage |  and this type of chemical screen mainly focuses on |  searching for protectors against cell death. To expand the |  candidate pool of HC protectors, a self-built acoustic
关键词: Acoustic escape response |  Zebrafish |  Lateral line |  Hair cell |  Low-frequency sound |  Functional screening |  STARTLE RESPONSE |  HEARING |  DAMAGE |  AMINOGLYCOSIDES...

10. Dentate Gyrus Morphogenesis is Regulated by an Autism Risk Gene Trio Function in Granule Cells

Sun, Mengwen |  Xue, Weizhen... -  《neuroscience bulletin》 - 2025,41(1) - 1~15 - 共15页

摘要:Autism Spectrum Disorders (ASDs) are reported |  as a group of neurodevelopmental disorders. The |  structural changes of brain regions including the |  hippocampus were widely reported in autistic patients and |  mouse models with dysfunction of ASD risk genes, but
关键词: Trio |  Autism spectrum disorders |  Dentate gyrus morphogenesis |  Neuron migration |  Spatial transcriptomic sequencing |  SPECTRUM DISORDER |  MATURATION |  MUTATIONS |  MIGRATION |  REELIN
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