全部 |
  • 全部
  • 题名
  • 作者
  • 机构
  • 关键词
  • NSTL主题词
  • 摘要
检索 二次检索 AI检索
展示更多
外文文献 中文文献
筛选条件:

1. Galactose-replacement unmasks the biochemical consequences of the G11778A mitochondrial DNA mutation of LHON in patient-derived fibroblasts NSTL国家科技图书文献中心

Pasqualotto, Bryce A... |  Tegeman, Carina... -  《Experimental Cell Research》 - 2024,439(1) - 共14页

摘要:Leber 's hereditary optic neuropathy (LHON) is |  a visual impairment associated with mutations of |  mitochondrial genes encoding elements of the electron |  transport chain. While much is known about the genetics of |  LHON, the cellular pathophysiology leading to retinal
关键词: LHON |  Galactose |  ATP |  Oxidative stress |  Proliferation |  Fibroblasts

2. MiR-92a-2-5p suppresses esophageal squamous cell carcinoma cell proliferation and invasion by targeting PRDX2 NSTL国家科技图书文献中心

Zhan, Xiang |  Li, Jixian... -  《Experimental Cell Research》 - 2024,435(1) - ARTN 113925~ - 共9页

摘要:MicroRNAs (miRNAs) can function as negative |  regulators of gene expression by binding to the 3 |  '-untranslated region (3 '-UTR) of target genes. The aberrant |  expression of miRNAs in neoplasm is extensively associated |  with tumorigenesis and cancer progression, including
关键词: MiRNA |  Esophageal squamous cell carcinoma |  Peroxiredoxin2 |  Protein kinase B/mammalian target of |  rapamycin |  Wnt/beta-catenin |  PEROXIREDOXINS |  MICRORNAS

3. Uncovering SIRT3 and SHMT2-dependent pathways as novel targets for apigenin in modulating colorectal cancer: In vitro and in vivo studies NSTL国家科技图书文献中心

Abdelmaksoud, Nourha... |  Abulsoud, Ahmed I.... -  《Experimental Cell Research》 - 2024,441(1) - 共12页

摘要:Despite significant advances in the treatment |  of colorectal cancer (CRC), identification of novel |  targets and treatment options are imperative for |  improving its prognosis and survival rates. The |  mitochondrial SIRT3 and SHMT2 have key roles in metabolic
关键词: Apigenin |  Apoptosis |  Colorectal cancer |  LINC01234 |  SHMT2 |  SIRT3

4. Generation of a stably transfected mouse embryonic stem cell line for inducible differentiation to excitatory neurons NSTL国家科技图书文献中心

Gu, Jinchao |  Rollo, Ben... -  《Experimental Cell Research》 - 2024,435(1) - ARTN 113902~ - 共8页 - 被引量:2

摘要:In vitro differentiation of stem cells into |  various cell lineages is valuable in developmental |  studies and an important source of cells for modelling |  physiology and pathology, particularly for complex tissues |  such as the brain. Conventional protocols for in
关键词: Embryonic stem cells |  neurogenin 2 |  PiggyBac |  inducible cell line |  neuronal differentiation

5. TAK-242 inhibits glioblastoma invasion, migration, and proneural-mesenchymal transition by inhibiting TLR4 signaling NSTL国家科技图书文献中心

Feng, Zibin |  Chen, Guangliang... -  《Experimental Cell Research》 - 2024,439(1) - 共12页

摘要:Resatorvid (TAK-242), a small-molecule |  inhibitor of Toll-like receptor 4 (TLR4), has the ability |  to cross the blood-brain barrier (BBB). In this |  study, we explored the role of TAK-242 on glioblastoma |  (GBM) invasion, migration, and proneural-mesenchymal
关键词: Glioma cells |  Invasion and migration abilities |  Proneural-mesenchymal transition |  Toll-like receptor 4

6. Characterization of the dehydrogenase-reductase DHRS2 and its involvement in histone deacetylase inhibition in urological malignancies NSTL国家科技图书文献中心

Mueller, Melanie R. |  Burmeister, Aaron... -  《Experimental Cell Research》 - 2024,439(1) - 共9页

摘要:Background: Being implicated during tumor |  migration, invasion, clonogenicity, and proliferation, the |  nicotinamide adenine dinucleotide (NAD)/-phosphate (NADP | )-dependent dehydrogenase/reductase member 2 (DHRS2) has |  been considered to be induced upon inhibition of
关键词: DHRS2 |  Histone deacetylase inhibitor |  Germ cell tumors |  Urothelial cancer |  Prostate cancer |  Renal cell carcinoma |  Lipid metabolism |  Energy metabolism

7. UBA5 inhibition restricts lung adenocarcinoma via blocking macrophage M2 polarization and cisplatin resistance NSTL国家科技图书文献中心

Xu, Dacai |  Zhang, Donghui... -  《Experimental Cell Research》 - 2024,440(2) - 共10页

摘要:UBA5, a ubiquitin-like activated enzyme |  involved in ufmylation and sumoylation, presents a viable |  target for pancreatic and breast cancer treatments, yet |  its role in lung adenocarcinoma (LUAD) remains |  underexplored. This study reveals UBA5's tumor-promoting
关键词: UBA5 |  Lung adenocarcinoma |  Cell growth |  Macrophage |  Cisplatin resistance

8. Exploring the in vivo anti-cancer potential of Neosetophomone B in leukemic cells using a zebrafish xenograft model NSTL国家科技图书文献中心

Kuttikrishnan, Shilp... |  Hasan, Maram... -  《Experimental Cell Research》 - 2024,435(1) - ARTN 113907~ - 共5页 - 被引量:1

摘要:Neosetophomone B (NSP-B) is a unique |  meroterpenoid fungal secondary metabolite that has previously |  demonstrated promising anti -cancer properties against |  various cancer cell lines in vitro. However, its in vivo |  anticancer potential remaines unexplored. To fill this gap
关键词: Cell proliferation |  Fungal secondary metabolites |  Neosetophomone B |  Zebrafish |  Xenograft model |  Leukemia

9. Raman spectroscopy analysis of human amniotic fluid cells from fetuses with myelomeningocele NSTL国家科技图书文献中心

Pontiggia, Luca |  Michalak-Micka, Kata...... -  《Experimental Cell Research》 - 2024,439(1) - 共11页

摘要:Prenatal surgery for the treatment of spina |  bifida (myelomeningocele, MMC) significantly enhances |  the neurological prognosis of the patient. To ensure |  better protection of the spinal cord by large defects | , the application of skin grafts produced with cells
关键词: Amniotic fluid stem cells |  Raman spectroscopy |  Spina bifida aperta |  Myelomeningocele |  cKit/CD117

10. Circular RNA SLC8A1 triggers hippocampal neuronal ferroptosis by regulating FUS-mediated ATF3 mRNA stability in epilepsy NSTL国家科技图书文献中心

Kang, Qin |  Zhang, Ji... -  《Experimental Cell Research》 - 2024,434(1) - ARTN 113848~ - 共10页 - 被引量:4

摘要:Background: Epilepsy is a neurological |  disorder characterized by recurrent seizures and is often |  unresponsive to current treatment options. Ferroptosis, a |  recently defined iron-dependent regulated cell death, has |  been suggested as a potential therapeutic target for
关键词: Epilepsy |  Ferroptosis |  FUS |  ATF3 |  EXPRESSION
检索条件出处:Experimental Cell Research

NSTL主题词

  • NSTL学科导航