NSTL国家科技图书文献中心

1. Metabolomics identifies metabolite markers in plasma and extracellular vesicles within plasma in patients with asthma NSTL国家科技图书文献中心

Chang, Chih-Jung | Ma, Qi-Wen ... - 《Clinica chimica acta》 - 2025,565 - 120010～120010 - 共10页

摘要：Background: Plasma and extracellular vesicles | (EVs) derived from plasma are important sources of | information regarding individual health. Metabolomic | analysis of plasma and EVs may provide new methods for | predicting disease occurrence. This study aims to analyze

关键词： Asthma | Extracellular vesicles | LC-MS | Metabolomics

2. Identification of novel variants in hereditary spherocytosis patients by whole-exome sequencing NSTL国家科技图书文献中心

Qin, Li | Jia, Yujiao ... - 《Clinica chimica acta》 - 2025,565 - 119989～119989 - 共10页

摘要：Defects in erythrocyte membrane proteins can | cause the most common type of inherited hemolytic | anemia, so called hereditary spherocytosis (HS). It is | characterized by the appearance of spherocytes in peripheral | blood, hemolytic anemia, splenomegaly, jaundice and

关键词： Hereditary spherocytosis | Hemolytic anemia | Gene mutation | Whole-exome sequencing (WES) | Next-generation sequencing (NGS)

3. Cherry-red plasma: Beyond the assumption of hemolysis NSTL国家科技图书文献中心

Chen, Lechuang | Zhang, Yu ... - 《Clinica chimica acta》 - 2025,564 - 119917～119917 - 共6页

摘要：Hemolysis is the most prevalent pre-analytical | interfering factor and a major source of error in laboratory | analysis. The examination of samples post-centrifugation | can provide valuable information regarding | preanalytical interferences. In this unusual case, a patient's

关键词： Cherry-red plasma | PV-10 | Rose bengal | Hemolysis | Interference

4. Methylated cell-free DNA as a novel biomarker in Alzheimer's disease NSTL国家科技图书文献中心

Zhen, Mengyang | Dang, Miao ... - 《Clinica chimica acta》 - 2025,566 - Article 120069～Article 120069 - 共4页

摘要：Due to an aging population, Alzheimer's | disease (AD), a neurodegenerative disorder, has affected | more than 40 million people worldwide, a figure | predicted to significantly increase in the coming decades | . Despite much effort to understand AD pathogenesis

关键词： Alzheimer's disease | Biomarker | Cell-free DNA | Methylation

5. A colorectal liver metastasis prediction model based on the combination of lipoprotein-associated phospholipase A2 and serum biomarker levels NSTL国家科技图书文献中心

Feng, Sisi | Zhou, Manli ... - 《Clinica chimica acta》 - 2025,568 - Article 120143～Article 120143 - 共8页

摘要：Objective: This study aims to assess the | predictive value of serum lipoprotein-associated | phospholipase A2 (LpPLA2) in colorectal liver metastasis (CRLM | ) patients. Methods: A total of 507 participants were | recruited for this study, comprising 162 healthy controls

关键词： Lp-PLA2 | Colorectal liver metastasis | Machine learning | Prediction model

6. Biosensors for early stroke detection NSTL国家科技图书文献中心

Alavian, Firoozeh | Khodabakhshi, Fateme...... - 《Clinica chimica acta》 - 2025,567 - Article 120079～Article 120079 - 共14页

摘要：This article aims to provide a comprehensive | review of the latest advances in biosensor technology | for early stroke diagnosis. Analyzing current | research from authoritative databases highlights the | significance of biosensors in improving stroke detection and

关键词： Biosensor | Stroke | Early diagnosis | Detection | Treatment | Clinical implementation

7. Systematic review and meta -analysis of biological variation data of urine albumin, albumin to creatinine ratio and other markers in urine NSTL国家科技图书文献中心

Aslan, Berna | Carobene, Anna ... - 《Clinica chimica acta》 - 2025,566 - Article 120032～Article 120032 - 共13页

摘要：Introduction: Significant variations in | Biological Variation (BV) estimates have been reported for | urine markers. This study aimed to systematically | review and critically appraise BV studies for albumin | , creatinine, albumin-to-creatinine ratio (ACR), and other

关键词： Albumin | Albumin to creatinine ratio | Analytical performance specifications | Biological variation | Creatinine | Albumin excretion rate | Meta-analysis

8. Circulating levels of PADs and citrullinated histone H3 in SARS-CoV-2 infection: Influence of genetic polymorphisms NSTL国家科技图书文献中心

Gutierrez-Perez, Ils... | Perez-Rubio, Gloria ... - 《Clinica chimica acta》 - 2025,569 - Article 120180～Article 120180 - 共10页

摘要：Background: Peptidyl arginine deiminases (PADs | ) and citrullinated H3 histone (H3Cit) play a crucial | role in the inflammatory response. These components | determine various clinical situations in COVID-2019 | associated pneumonia. Single nucleotide polymorphisms (SNPs

关键词： PADI2 | PADI4 | Citrulinated histone H3 | SARS-CoV-2 | Invasive mechanical ventilation | Non-survival

9. Heterogeneity in benign and malignant salivary gland tumors NSTL国家科技图书文献中心

Ghasemian, Mehdi | Gholami, Mohammad Am...... - 《Clinica chimica acta》 - 2025,572 - 120258～120258 - 共8页

摘要：Advanced proteomics tools have identified the | role of proteins in cancer biology, highlighting the | importance of these molecules for biomarker discovery and | providing valuable insights into cancer diagnosis | , prognosis, and targeted therapy. Proteome analysis of

关键词： Salivary gland tumors | Protein | Proteomics | Tumor biomarkers

10. Haptoglobin phenotype: A germline risk factor for malignant pleural mesothelioma? A case-control study NSTL国家科技图书文献中心

Lamote, Kevin | Delanghe, Sigurd ... - 《Clinica chimica acta》 - 2025,573 - Article 120309～Article 120309 - 共6页

摘要：Purpose: The pathogenesis of malignant pleural | mesothelioma (MPM) is linked to asbestos-induced chronic | inflammation, oxidant formation, hemolysis and subsequent | hemoglobin (Hb) release, potentiating oxidative injury | . Haptoglobin (Hp) serves as a major antioxidant by binding