NSTL国家科技图书文献中心

1. Investigating tumor-host response dynamics in preclinical immunotherapy experiments using a stepwise mathematical modeling strategy NSTL国家科技图书文献中心

Jarrett, Angela M. | Song, Patrick N.... - 《Mathematical Biosciences: An International Journal》 - 2023,366 - ARTN 109106～ - 共15页 - 被引量：1

摘要：Immunotherapies such as checkpoint blockade to PD1 and CTLA4 can have varied effects on individual tumors. To quantify the successes and failures of these therapeutics, we developed a stepwise mathema...

关键词： FMISO-PET | Imaging | Immune response | Computational | Hypoxia | E0771 | MC38 | CANCER | HYPOXIA | RESISTANCE...

2. Longitudinal FRET Imaging of Glucose and Lactate Dynamics and Response to Therapy in Breast Cancer Cells NSTL国家科技图书文献中心

Yang, Jianchen | Davis, Tessa ... - 《Molecular imaging and biology: MIB : the official publication of the Academy of Molecular Imaging》 - 2022,24(1) - 144～155 - 共12页 - 被引量：3

摘要：Purpose The reprogramming of cellular metabolism is a hallmark of cancer. The ability to noninvasively assay glucose and lactate concentrations in cancer cells would improve our understanding of the d...

关键词： Fluorescence | Time-resolved microscopy | MDA-MB-231 | Metabolism | Oncometabolite | Hypoxia | Warburg effect | TRANSPORTER | SENSITIVITY | GLYCOLYSIS...

3. Differences Between Ipsilateral and Contralateral Early Parenchymal Enhancement Kinetics Predict Response of Breast Cancer to Neoadjuvant Therapy NSTL国家科技图书文献中心

Ren, Zhen | Pineda, Federico D.... - 《Academic radiology》 - 2022,29(10) - 1469～1479 - 共11页 - 被引量：3

摘要：Rationale and Objectives: To determine whether kinetics measured with ultrafast dynamic contrast-enhanced magnetic resonance imaging in tumor and normal parenchyma pre- and post-neoadjuvant therapy (N...

关键词： breast cancer imaging | ultrafast dynamic contrast enhanced MRI (DCE-MRI) | background parenchymal enhancement (BPE) | background parenchymal kinetics | bilateral asymmetry | DCE-MRI | TUMOR RESPONSE | CHEMOTHERAPY | ASSOCIATION | ULTRAFAST...

4. An in silico validation framework for quantitative DCE-MRI techniques based on a dynamic digital phantom SCOPUS Scopus数据库 SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Wu, Chengyue | Hormuth, David A., I...... - 《Medical image analysis》 - 2021,73 - 共17页 - 被引量：4

摘要：Quantitative evaluation of an image processing method to perform as designed is central to both its utility and its ability to guide the data acquisition process. Unfortunately, these tasks can be qui...

关键词： Computational fluid dynamics | Kidney | MRI simulator | Quantitative MRI | Pharmacokinetics | Hemodynamics

5. Simulating the spread of COVID-19 via a spatially-resolved susceptible-exposed-infected-recovered-deceased (SEIRD) model with heterogeneous diffusion SCOPUS Scopus数据库 SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Viguerie, Alex | Lorenzo, Guillermo ... - 《Applied mathematics letters》 - 2021,111 - 共9页 - 被引量：88

摘要：We present an early version of a Susceptible-Exposed-Infected-Recovered-Deceased (SEIRD) mathematical model based on partial differential equations coupled with a heterogeneous diffusion model. The mo...

关键词： Partial differential equations | Mathematical epidemiology | Compartmental models | COVID-19 | Mathematical modeling | Mathematical biology

6. The rate of breast fibroglandular enhancement during dynamic contrast-enhanced MRI reflects response to neoadjuvant therapy SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Virostko, John | Kuketz, Garrett ... - 《European Journal of Radiology》 - 2021,136 - 共7页 - 被引量：3

摘要：Purpose: This study assesses the rate of enhancement of breast fibroglandular tissue after administration of a magnetic resonance imaging (MRI) gadolinium-based contrast agent and determines its relat...

关键词： Breast cancer | Fibroglandular | Ipsilateral | BPE | NAT

7. Integrating transcriptomics and bulk time course data into a mathematical framework to describe and predict therapeutic resistance in cancer SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Johnson, Kaitlyn E. | Howard, Grant R.... - 《Physical biology》 - 2021,18(1) - 共18页 - 被引量：9

摘要：A significant challenge in the field of biomedicine is the development of methods to integrate the multitude of dispersed data sets into comprehensive frameworks to be used to generate optimal clinica...

关键词： mathematical modeling | mathematical oncology | chemoresistance | intratumor heterogeneity | population dynamic

8. A coupled mass transport and deformation theory of multi-constituent tumor growth SCOPUS Scopus数据库 EI 工程索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

Faghihi, Danial | Feng, Xinzeng ... - 《Journal of the Mechanics and Physics of Solids》 - 2020,139 - 共31页 - 被引量：18

摘要：We develop a general class of thermodynamically consistent, continuum models based on mixture theory with phase effects that describe the behavior of a mass of multiple interacting constituents. The c...

关键词： Mixture theory | Phase-field | Hyperelastic solid | Biochemomechanical coupling | Tumor growth

9. Patient-Specific Characterization of Breast Cancer Hemodynamics Using Image-Guided Computational Fluid Dynamics SCOPUS Scopus数据库 SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Wu, Chengyue | Hormuth, David A.... - 《IEEE Transactions on Medical Imaging》 - 2020,39(9) - 2760～2771 - 共12页 - 被引量：16

摘要：The overall goal of this study is to employ quantitative magnetic resonance imaging (MRI) data to constrain a patient-specific, computational fluid dynamics (CFD) model of blood flow and interstitial ...

关键词： Magnetic resonance imaging | Tumors | Computational fluid dynamics | Computational modeling | Cancer | Hemodynamics | Tumor | 1D-3D coupled | blood flow | interstitial fluid pressure...

10. Diffusion-reaction compartmental models formulated in a continuum mechanics framework: application to COVID-19, mathematical analysis, and numerical study SCOPUS Scopus数据库 SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Viguerie, Alex | Veneziani, Alessandr...... - 《Computational Mechanics: Solids, Fluids, Fracture Transport Phenomena and Variational Methods》 - 2020,66(5) - 1131～1152 - 共22页 - 被引量：48

摘要：The outbreak of COVID-19 in 2020 has led to a surge in interest in the research of the mathematical modeling of epidemics. Many of the introduced models are so-calledcompartmental models, in which the...