NSTL国家科技图书文献中心

1. A nuclear-driven combined cooling and power system based on supercritical and transcritical CO2 cycles: energy, exergy, and exergoeconomic analysis, multi-objective optimization and reactor startup analysis NSTL国家科技图书文献中心

Wang, Mengxuan | Wang, Jiangfeng ... - 《Nuclear engineering and design》 - 2025,432(Feb.) - 1.1～1.18 - 共18页 - 被引量：1

摘要：Energy cascade utilization is deemed as one of the most efficient paths to cope with energy crises and improve energy efficiency. To further analyze the application and performance of the multi-genera...

关键词： Nuclear energy | Combined cooling and power system | Thermodynamic and exergoeconomic analysis | Multi-objective optimization | Reactor startup analysis | WASTE HEAT-RECOVERY | REFRIGERATION CYCLE | THERMODYNAMIC ANALYSIS | CORE DESIGN

2. Convective heat transfer enhancement by combination effect of twist and helix in helical twisted tubes NSTL国家科技图书文献中心

Wang, Mengxuan | Li, Xiuzhen ... - 《Thermal science and engineering progress》 - 2025,60 - 共20页

摘要：A novel heat exchange element-helical twisted tube (HTT) is proposed, and its novelty is reflected in the heat transfer enhancement brought about by the coupled deformation effect of helix and twist. ...

关键词： Helical twisted tube | Heat transfer enhancement | Numerical simulation | Entropy production analysis

3. Synthesis of novel deuterated EGFR/ALK dual-target inhibitors and their activity against non-small cell lung cancer NSTL国家科技图书文献中心

Nie, Haoran | Zhang, Shuai ... - 《European Journal of Medicinal Chemistry》 - 2025,283 - 117146～117146 - 共19页

摘要：EGFR and ALK are common driver genes in NSCLC, and more patients with these mutations are being identified due to medical advances. Thus, developing dual-target EGFR/ALK inhibitors is crucial. In this...

关键词： NSCLC | EGFR | ALK | Dual-target inhibitors | Deuterated

4. Weaning causes imbalanced T lymphocyte distribution and impaired intestinal immune barrier function in piglets NSTL国家科技图书文献中心

Dong, Li | Wang, Mengxuan ... - 《Animal Production Science》 - 2024,64(2) - ARTN AN22471～ - 共13页

摘要：Context. The immune system of piglets is not fully developed at weaning. The immature adaptive immune system along with the change in the feed types and the living conditions make piglets susceptible ...

关键词： cytokines | immunity | intestine | Notch2 | nutrition | pigs | T lymphocytes | weaning | INFLAMMATORY CYTOKINES | UP-REGULATION...

5. Metabolic engineering of glycolysis in Escherichia coli for efficient production of patchoulol and tau-cadinol NSTL国家科技图书文献中心

Zhou, Li | Wang, Qin ... - 《Bioresource Technology: Biomass, Bioenergy, Biowastes, Conversion Technologies, Biotransformations, Production Technologies》 - 2024,391(Pt.B) - ARTN 130004～ - 共12页 - 被引量：3

摘要：Glucose metabolism suppresses the microbial synthesis of sesquiterpenes with a syndrome of "too much of a good thing can be bad". Here, patchoulol production in Escherichia coli was increased 2.02 tim...

关键词： Carbon catabolite repression | Overflow metabolism | Patchoulol | tau-Cadinol | Escherichia coli | Dynamic metabolic engineering | T-CADINOL | FUNCTIONAL-CHARACTERIZATION | OVERFLOW METABOLISM | POGOSTEMON-CABLIN...

6. Perfluorocarbon-Encapsulated Porphyrin-Lipid Nanoparticles as a Photoactive Pyroptosis Inducer for Cancer Therapy NSTL国家科技图书文献中心

Lin, Xiaona | Jiang, Xinpeng ... - 《Journal of biomedical nanotechnology》 - 2023,19(1) - 28～35 - 共8页

摘要：Pyroptosis is a unique mode of programmed cell death extensively accepted to outperform apoptosis in inducing rapid cell death and evoking potent immune responses for further inhibiting tumor progress...

关键词： Pyroptosis | Photodynamic Therapy | Cancer | Porphyrin-Lipid Nanoparticle | Perfluorocarbon

7. A New Neuro-Optimal Nonlinear Tracking Control Method via Integral Reinforcement Learning with Applications to Nuclear Systems EI 工程索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

Zhong, Weifeng | Wang, Mengxuan ... - 《Neurocomputing》 - 2022,483(Apr.28) - 361～369 - 共9页 - 被引量：11

摘要：In this paper, a new infinite horizon optimal tracking control method for continuous-time nonlinear sys-tems is given using an actor-critic structure. This present integral reinforcement learning (IRL...

关键词： Integral reinforcement learning | Nuclear power reactor | Nonlinear system | Optimal tracking control | Neural networks

8. O-GlcNAc transferase Ogt regulates embryonic neuronal development through modulating Wnt/beta-catenin signaling SCIE Web of Science核心 NSTL国家科技图书文献中心

Shen, Hui | Zhao, Xingsen ... - 《Human Molecular Genetics》 - 2022,31(1) - 57～68 - 共12页 - 被引量：18

摘要：Ogt-mediated O-GlcNAcylation is enriched in the nervous system and involves in neuronal development, brain function and neurological diseases. However, the roles of Ogt and O-GlcNAcylation in embryoni...

关键词： GLCNACYLATION | GLYCOSYLATION | PHOSPHORYLATION | IDENTIFICATION | ORGANOIDS | PRECURSOR | PROMOTES

9. ParallelNet: multiple backbone network for detection tasks on thigh bone fracture SCIE Web of Science核心 EI 工程索引 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Wang, Mengxuan | Yao, Jinkun ... - 《Multimedia systems》 - 2021,27(6) - 1091～1100 - 共10页 - 被引量：7

摘要：In this paper, a novel two-stage R-CNN network called ParallelNet is proposed for thigh fracture detection task. In the proposed method, multiple parallel backbone networks and a feature fusion connec...

关键词： Thigh fracture detection | Deep learning | Parallel backbone networks | Dilated convolution

10. Human group A rotavirus P[25] VP8*specifically binds to A-type histo-blood group antigen SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Li, Dandi | Wang, Mengxuan ... - 《Virology》 - 2021,555 - 56～63 - 共8页 - 被引量：5

摘要：Rotavirus (RV) is a common cause of acute gastroenteritis in young children. While P[8] and P[4] are the most prevalent RV genotypes in humans, other genotypes are also reported in human infections oc...