Thissera, Bathini |  Soldatou, Sylvia... -  《Journal of applied microbiology》 - 2025,136(1) - 共22页

摘要：Expansion of the microbial drug discovery pipeline has been impeded by a limited and skewed appreciation of the microbial world and its full chemical capabilities and by an inability to induce silent ...

关键词： induction of microbial natural products |  quorum sensing |  epigenetic modulation |  ribosome engineering

Moore, Jane |  Jayakumar, Anjali... -  《Environmental Science & Technology: ES&T》 - 2023,57(43) - 16372～16385 - 共14页 - 被引量：2

摘要：Climate change and high eutrophication levels of freshwater sources are increasing the occurrence and intensity of toxic cyanobacterial blooms in drinking water supplies. Conventional water treatment ...

关键词： biological water treatment |  eutrophication |  waste valorization |  microcystins |  biodegradation |  microbiome |  MICROCYSTIN-LR |  DRINKING-WATER |  ACTIVATED CARBON |  BIODEGRADATION...

Parra, Jonathan |  Soldatou, Sylvia... -  《International Journal of Systematic and Evolutionary Microbiology》 - 2021,71(9) - 共8页 - 被引量：5

摘要：The actinomycetes strains KRD168T and KRD185T were isolated from sediments collected from the deep Southern Ocean and, in this work, they are described as representing two novel species of the genus P...

关键词： Actinobacteria |  ocean |  Pseudonocardia |  sediments |  DEOXYRIBONUCLEIC-ACID |  EMENDED DESCRIPTION |  DNA |  WIDESPREAD |  DIVERSITY |  SEQUENCES...

Jayakumar, Anjali |  Wurzer, Christian... -  《Science of the Total Environment》 - 2021,796 - 共13页 - 被引量：26

摘要：Cost-effective, efficient, and sustainable water treatment solutions utilising existing materials and technology will make it easier for low and middle-income countries to adopt them, improving public...

关键词： Biologically-enhanced biochar |  Biological water treatment |  Biochar-microbial interactions |  Sequential biochar systems

Soldatou, Sylvia |  Eldjarn, Grimur Hjor...... -  《FEMS Microbiology Letters》 - 2019,366(13) - 共8页 - 被引量：15

摘要：Secondary metabolites can be viewed as a chemical language, facilitating communication between microorganisms. From an ecological point of view, this metabolite exchange is in constant flux due to evo...

关键词： secondary metabolites |  specialised metabolites |  biosynthetic gene clusters |  genome mining |  comparative metabolomics

Millan-Aguinaga, Nat... |  Soldatou, Sylvia... -  《Microbiology》 - 2019,165(11) - 1169～1180 - 共12页 - 被引量：12

摘要：Polar and subpolar ecosystems are highly vulnerable to global climate change with consequences for biodiversity and community composition. Bacteria are directly impacted by future environmental change...

关键词： Actinobacteria |  specialized metabolites |  marine |  Antarctic |  Arctic |  evolution

Soldatou, Sylvia |  Baker, Bill J. -  《Natural product reports》 - 2017,34(6) - 585～626 - 共42页 - 被引量：4

摘要：This is an update report on marine natural products isolated from cold-water organisms in the last decade, following the previous review that covered the literature up to 2005. Emphasis is given to th...

Diyaolu, Oluwatofunm... |  Oluwabusola, Emmanue...... -  《molecules》 - 2022,27(23) - 共20页

摘要：The Nigerian Niger-Delta crude oil exploration often results in spills that affect indigenous medicinal plant biodiversity, likely changing the phytochemical profile of surviving species, their bioact...

关键词： Vernonia amygdalina leaves |  Ocimum gratissimum leaves |  UPLC-QTOF-MS |  sickle cell anaemia |  molecular docking |  metabolomics |  pharmacophore |  drug design |  in silico |  SICKLE...

Laguionie-Marchais, ... |  Allcock, A. Louise... -  《marine drugs》 - 2022,20(1) - 共15页

摘要：Phylum Cnidaria has been an excellent source of natural products, with thousands of metabolites identified. Many of these have not been screened in bioassays. The aim of this study was to explore the ...

关键词： ADME |  chemical space |  drug-likeness |  MarinLit |  multivariate |  rule-of-five |  virtual screening |  SOFT CORAL |  DISCOVERY |  LIBRARIES...

Soldatou, Sylvia |  Eldjarn, Grimur Hjor...... -  《marine drugs》 - 2021,19(2) - 共21页

摘要：Biosynthetic and chemical datasets are the two major pillars for microbial drug discovery in the omics era. Despite the advancement of analysis tools and platforms for multi-strain metabolomics and ge...

关键词： Actinobacteria |  marine |  Polar |  genomics |  metabolomics |  specialised metabolites |  NATURAL-PRODUCT DISCOVERY |  MOLECULAR NETWORKING |  GENE CLUSTERS |  BIOSYNTHETIC-PATHWAY...