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1. Robust antiviral innate immune response and miRNA regulatory network were identified in ZIKV-infected cells: implications in the pathogenesis of ZIKV infection NSTL国家科技图书文献中心

Lai, Mingshuang |  Lai, Rongji... -  《Virus Genes》 - 2025,61(3) - 249~264 - 共16页

摘要:Zika virus (ZIKV) infection has emerged as a significant public health concern due to its association with fetal microcephaly and Guillain-Barre syndrome (GBS). Unfortunately, its detailed pathogenesi...
关键词: Bioinformatics analysis |  Zika virus (ZIKV) |  Differentially expressed genes (DEGs) |  Interferon-stimulated genes (ISGs) |  Innate immune response

2. Global Burden and Trends of Acute Hepatitis C From 1990 to 2021: An Analysis Based on the 2021 Global Burden of Disease Study NSTL国家科技图书文献中心

Wang, Xinwei |  Yan, Xipeng... -  《Journal of viral hepatitis.》 - 2025,32(5) - e70026~e70026 - 共13页

摘要:Acute hepatitis C (AHC) represents a considerable challenge to global public health, although direct-acting antiviral (DAA) therapy has substantially improved therapeutic outcomes for hepatitis C viru...
关键词: acute hepatitis C |  epidemiology |  global burden of disease |  trend

3. Preliminary survey of three mosquito-borne viruses using a self-established multiplex RT-qPCR assay in Chinese blood donors NSTL国家科技图书文献中心

Yan, Xipeng |  Wang, Xinwei... -  《Journal of Virological Methods》 - 2025,331 - 115055~115055 - 共5页

摘要:Background: Mosquito-borne pathogens pose a significant threat to both human health and blood safety. The primary mosquito-borne viruses that present this threat are Zika virus, Chikungunya virus, and...
关键词: Mosquito borne virus |  Blood donor |  Blood safety |  Arbovirus disease monitoring |  Single-tube multiplex RT-qPCR

4. Establishment of a Cleavage-Based Single-Plasmid Dual-Luciferase Surrogate Reporter for the Cleavage Efficiency Evaluation of CRISPR-Cas12a Systems and Its Primary Application NSTL国家科技图书文献中心

Shi, Yaoqiang |  Tan, Qi... -  《The CRISPR Journal》 - 2024,7(3) - 156~167 - 共12页

摘要:CRISPR-Cas technology is a widely utilized gene-editing tool that involves gRNA-guided sequence recognition and Cas nuclease-mediated cleavage. The design and evaluation of gRNA are essential for enha...
关键词: CRISPR

5. Identification and validation of ferroptosis-related genes in patients infected with dengue virus: implication in the pathogenesis of DENV NSTL国家科技图书文献中心

Li, Jinlian |  Yan, Xipeng... -  《Virus Genes》 - 2023,59(3) - 377~390 - 共14页 - 被引量:3

摘要:Ferroptosis, an iron-dependent form of regulated cell death, has been associated with many virus infections. However, the role of ferroptosis in dengue virus (DENV) infection remains to be clarified. ...
关键词: Dengue virus (DENV) |  Ferroptosis |  Bioinformatics analysis |  Differentially expressed genes (DEGs) |  Ferroptosis-related genes |  CELLS

7. Role of Exosomal Modulation of Macrophages in Liver Fibrosis

Fan, Bin |  Xie, He... -  《Journal of Clinical and Translational Hepatology》 - 2024,12(2) - 201~209 - 共9页

摘要:Exosomes are 60-120 nm diameter double-membrane lipid organelles discharged by cells. Various studies have shown that exosomes exert multiple functions in both physical and diseased processes, such as...
关键词: Exosome |  Macrophage |  Liver fibrosis |  Hepatocyte |  Mesenchymal stem cell |  Hepatic stellate cell |  EXTRACELLULAR VESICLES |  INJURY |  POLARIZATION |  EXPRESSION...

8. Cost-benefit analysis of serological and nucleic acid testing for hepatitis B virus in blood donors in southern China

Ye, Xianlin |  Xiong, Wen... -  《BMC Infectious Diseases》 - 2024,24(1) - 共9页 - 被引量:1

摘要:BackgroundMost Chinese blood centers have implemented mini pool (MP) HBV nucleic acid testing (NAT) together with HBsAg ELISA in routine blood donor screening for HBV infection since 2015, and a few c...
关键词: Blood screening |  Hepatitis B |  Cost-effectiveness analysis |  Nuleic acid testing |  Mini pool |  Individual donation |  Occult hepatitis B infection |  HUMAN-IMMUNODEFICIENCY-VIRUS |  INFECTION |  DONATIONS...
检索条件作者:He, Baoren

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