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1. Characteristics of VA hospitals by participation status in a large pragmatic embedded clinical trial NSTL国家科技图书文献中心

Dupuis, Genevieve |  Ferguson, Ryan E.... -  《Contemporary clinical trials》 - 2025,148 - 107755~107755 - 共5页

摘要:Background: The Diuretic Comparison Project (DCP) was a multi-center, embedded pragmatic trial conducted within the VA healthcare system comparing chlorthalidone and hydrochlorothiazide in preventing ...
关键词: Pragmatic clinical trial |  Recruitment |  Engagement

2. Efficacy and Safety of Allopurinol and Febuxostat in Patients With Gout and CKD: Subgroup Analysis of the STOP Gout Trial NSTL国家科技图书文献中心

Helget, Lindsay N. |  Davis-Karim, Anne... -  《American Journal of Kidney Diseases》 - 2024,84(5) - 538~545 - 共8页

摘要:Rationale & Objective: We conducted a pre- specified examination of the efficacy and safety of allopurinol and febuxostat administered using a treat-to-target strategy in trial participants with chron...
关键词: Allopurinol |  chronic kidney disease |  febuxostat |  gout |  urate-lowering therapy

3. Estimating the per-protocol effect of lithium on suicidality in a randomized trial of individuals with depression or bipolar disorder NSTL国家科技图书文献中心

Szmulewicz, Alejandr... |  Madenci, Arin... -  《Journal of psychopharmacology》 - 2023,37(6) - 539~544 - 共6页

摘要:Background: The CSP590 randomized trial was designed to estimate the effect of lithium on suicidality. After a third of the intended number of participants were enrolled, the hazard ratio of suicidali...
关键词: Suicide |  lithium |  randomized trial |  per-protocol effect |  adherence |  PREVENTION |  RISK

4. Patient- reported reasons for non-participation in a COVID-19 therapeutics clinical trial: Findings from a multi-center investigation NSTL国家科技图书文献中心

Dassum, Samira Reyes |  Ferguson, Ryan... -  《Contemporary clinical trials》 - 2023,126 - 107082~107082 - 共6页

摘要:Background: Early in the pandemic, there were no evidence-based treatments for SARS-CoV-2, creating an urgent need to identify effective therapeutics. However, public participation in medical research...
关键词: COVID-19 |  IL-6 receptor inhibitor |  Therapeutics trial |  Clinical trial |  Enrollment rates |  Clinical trial participation |  Recruitment rates |  PARTICIPATION |  OPPORTUNITIES |  ENROLLMENT...

5. Ascertainment of stroke from administrative data to support a pragmatic embedded clinical trial NSTL国家科技图书文献中心

Raju, Srihari |  Hau, Cynthia... -  《Contemporary clinical trials》 - 2023,130 - 107214~107214 - 共8页 - 被引量:3

摘要:The goal of this observational study was to identify stroke hospitalizations using International Classification of Disease (ICD)-10 codes and use these codes to develop an ascertainment algorithm for ...
关键词: ICD-10 codes |  Stroke |  Administrative data |  Ascertainment |  ACUTE ISCHEMIC-STROKE |  INTERNATIONAL-CLASSIFICATION |  DIAGNOSIS CODES |  VALIDATION |  ACCURACY |  VALIDITY...

6. Temperature Changes During Electrophysiology Ablation in Veterans and 1-Year Success Rates: A Retrospective Pilot Analysis NSTL国家科技图书文献中心

Schumann, Roman |  Yuyun, Matthew... -  《Journal of cardiothoracic and vascular anesthesia》 - 2023,37(9) - 1646~1650 - 共5页

摘要:Objectives: The authors hypothesized that body core temperature during cardiac arrhythmia procedures in the electrophysiology laboratory declines, and examined the association of changes with the pati...
关键词: Words |  electrophysiology lab |  catheter ablation |  atrial fibrillation |  1-year ablation success |  core temperature |  general anesthesia |  PERIOPERATIVE HYPOTHERMIA

7. Impact of multi-site clinical trial results on clinical practice: Use of risperidone to treat PTSD nationally in the veterans health administration NSTL国家科技图书文献中心

Rosenheck, Robert |  Kurtz, Stephen G.... -  《Psychiatry research》 - 2023,321 - 115071~115071 - 共6页

摘要:Multi-site randomized effectiveness trials evaluate treatments under real-world conditions. Whether results change practice is under-studied. A 6-month 26-site Veterans Health Administration (VHA) coo...
关键词: Antipsychotics |  Dissemination |  Veterans |  Veterans health administration |  Va cooperative studies |  Randomized effectiveness trials |  Mental health systems |  PTSD pharmacotherapy |  POSTTRAUMATIC-STRESS-DISORDER |  ANTIPSYCHOTICS

8. Practical issues in pragmatic trials: the implementation of the Diuretic Comparison Project NSTL国家科技图书文献中心

Ferguson, Ryan E. |  Leatherman, Sarah M.... -  《Clinical trials: journal of the Society for Clinical Trials》 - 2023,20(3) - 276~283 - 共8页 - 被引量:1

摘要:Background/Aims: The US Department of Veterans Affairs Point of Care Clinical Trial Program conducts studies that utilize informatics infrastructure to integrate clinical trial protocols into routine ...
关键词: Pragmatic trials |  clinical trials |  point of care trials |  hypertension |  diuretics |  CLINICAL-TRIALS |  POINT

9. Creatinine standardization: a key consideration in evaluating whole blood creatinine monitoring systems for CKD screening SCIE Web of Science核心 EI 工程索引 NSTL国家科技图书文献中心

Dalton, Raymond Neil |  Isbell, Timothy Scot...... -  《Analytical and bioanalytical chemistry》 - 2022,414(10) - 3279~3289 - 共11页 - 被引量:4

摘要:Early detection of CKD using point of care creatinine and eGFR testing improves patient management outcomes. We undertook a field study to evaluate the use of a whole blood creatinine/eGFR device to s...
关键词: Stable isotope dilution liquid chromatography mass spectrometry |  Creatinine |  Traceability |  Standardization |  CHRONIC KIDNEY-DISEASE |  PREVALENCE |  BURDEN |  DEVICE |  COSTS |  POINT

10. Lithium Treatment in the Prevention of Repeat Suicide-Related Outcomes in Veterans With Major Depression or Bipolar Disorder A Randomized Clinical Trial SSCI 社会科学引文索引 SCIE Web of Science核心 NSTL国家科技图书文献中心

Katz, Ira R. |  Rogers, Malcolm P.... -  《JAMA psychiatry》 - 2022,79(1) - 24~32 - 共9页 - 被引量:30

摘要:IMPORTANCE Suicide and suicide attempts are persistent and increasing public health problems. Observational studies and meta-analyses of randomized clinical trials have suggested that lithium may prev...
关键词: BEHAVIOR |  RISK |  SCALE |  METAANALYSIS |  THOUGHTS |  VALIDITY
检索条件作者:Ferguson, Ryan

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