NSTL国家科技图书文献中心

1. Pharmacology and pharmacokinetics of antibody-drug conjugates, where do we stand? NSTL国家科技图书文献中心

Geraud, Arthur | Gougis, Paul ... - 《Cancer Treatment Reviews》 - 2025,135 - 102922～102922 - 共15页

摘要：Antibody-drug conjugates (ADCs) are a rising therapeutic class in oncology and hematology, with eleven drugs approved by the US Food and Drug Administration as of January 2025. These "magic bullets" h...

关键词： Antibody-dug conjugate (ADC) | Pharmacokinetics | Pharmacodynamics | Exposure-efficacy relationship (EER) | Exposure-safety relationship (ESR) | Therapeutic drug monitoring (TDM)

Collineau, Berenice | Goncalves, Anthony ... - 《Bulletin du Cancer: Journal de l'Association Francaise pour l'Etude du Cancer》 - 2024,111(7/8) - 765～781 - 共17页

摘要：Therapeutic options for breast cancer have recently been enriched by new antibody-drug conjugates (ADC), which are now being utilized across all known molecular subtypes. ADCs represent a groundbreaki...

关键词： Antibody drug conjugate | Breast cancer | Safety | Toxicity | TRASTUZUMAB EMTANSINE | SACITUZUMAB GOVITECAN | OPEN-LABEL | DERUXTECAN | IMMUNOCONJUGATE | PHASE-1

3. A 2023 inventory in oncology news NSTL国家科技图书文献中心

Bay, Jacques-Olivier | Auberger, Benjamin ... - 《Bulletin du Cancer: Journal de l'Association Francaise pour l'Etude du Cancer》 - 2024,111(1) - 18～32 - 共15页

摘要：In 2023, the improvement of our therapeutic management has largely taken shape. The aim of our article is to highlight the major advances that will change our practices. These are not only in the fiel...

关键词： New treatments in | oncology | Updates in 2023 | OPEN-LABEL | PLUS CHEMOTHERAPY | HODGKIN LYMPHOMA | PHASE-III | CANCER | PEMBROLIZUMAB | CARCINOMA...

4. Medical thesis publication of medical oncology residents in France: Trends and associated factors SCIE Web of Science核心 NSTL国家科技图书文献中心

de Nonneville, Alexa... | Bertucci, Francois ... - 《Bulletin du Cancer: Journal de l'Association Francaise pour l'Etude du Cancer》 - 2022,109(4) - 409～423 - 共15页

摘要：Introduction > The French medical residency system requires the completion and subsequent defense of a thesis. Only a minority of this work is eventually published in an peer-reviewed journal. The mai...

关键词： Medical Oncology | Medical studies | Residency | Medical thesis | Publication

5. Adjuvant chemotherapy for small, lymph node-negative, triple-negative breast cancer: A single-center study and a meta-analysis of the published literature SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

An, Xin | Lei, Xuefen ... - 《Cancer: A Journal of the American Cancer Society》 - 2020,126(S16) - 3837～3846 - 共10页

摘要：Background Current guidelines recommend adjuvant chemotherapy for patients with small, lymph node-negative, triple-negative breast cancer (TNBC) measuring >5 mm (T1b disease), but clinical evidence to...

关键词： adjuvant chemotherapy | lymph node-negative | meta-analysis | small | single-center study | triple-negative breast cancer

6. Isolated ipsilateral local recurrence of breast cancer: predictive factors and prognostic impact SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Houvenaeghel, Gilles | de Nonneville, Alexa...... - 《Breast cancer research and treatment.》 - 2019,173(1) - 111～122 - 共12页

摘要：BackgroundTumour features associated with isolated invasive breast cancer (BC) ipsilateral local recurrence (ILR) after breast conservative treatment (BCT) and consequences on overall survival (OS) ar...

关键词： Ipsilateral | Local recurrence | Breast cancer | Survival | Prognosis

7. Adjuvant chemotherapy in lobular carcinoma of the breast: a clinicopathological score identifies high-risk patient with survival benefit SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

de Nonneville, Alexa... | Jauffret, Camille ... - 《Breast cancer research and treatment.》 - 2019,175(2) - 379～387 - 共9页

摘要：BackgroundInvasive lobular carcinomas (ILCs) represent approximately 10% of all breast cancers. Despite this high frequency, benefit of adjuvant chemotherapy (CT) is still unclear.MethodsOur objective...

关键词： Adjuvant chemotherapy | Breast cancer | Lobular | Hormone receptor-positive

8. Homeopathy in cancer patients: What does the "best'' evidence tell us? SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

de Nonneville, Alexa... | Goncalves, Anthony - 《Bulletin du Cancer: Journal de l'Association Francaise pour l'Etude du Cancer》 - 2018,105(4) - 426～430 - 共5页

摘要：Homeopathic medicines are used by many patients with cancer, usually alongside conventional treatment. A recent report by the European Academies' Science Advisory Council concluded that "that there ar...

关键词： Homeopathy | Cancer | Complementary and alternative medication | Treatments | Adverse events

9. Benefit of adjuvant chemotherapy with or without trastuzumab in pT1ab node-negative human epidermal growth factor receptor 2-positive breast carcinomas: results of a national multi-institutional study SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

de Nonneville, Alexa... | Goncalves, Anthony ... - 《Breast cancer research and treatment.》 - 2017,162(2) - 307～316 - 共10页

摘要：Benefit of adjuvant trastuzumab-based chemotherapy for node-positive and/or > 1 cm human epidermal growth factor receptor 2-positive (HER2+) breast carcinomas has been clearly demonstrated in randomiz...

关键词： Subcentimetric breast cancer | HER2 | Adjuvant chemotherapy | Trastuzumab

10. Tailoring chemoimmunotherapy de-escalation in early-stage triple-negative breast cancer NSTL国家科技图书文献中心

Goncalves, Anthony | de Nonneville, Alexa... - 《The lancet oncology》 - 2025,26(3) - 273～274 - 共2页

摘要：Antibody-drug conjugates (ADCs) are a rising therapeutic class in oncology and hematology, with eleven drugs approved by the US Food and Drug Administration as of January 2025. These "magic bullets" h...

关键词： Antibody-dug conjugate (ADC) | Pharmacokinetics | Pharmacodynamics | Exposure-efficacy relationship (EER) | Exposure-safety relationship (ESR) | Therapeutic drug monitoring (TDM)

摘要：Therapeutic options for breast cancer have recently been enriched by new antibody-drug conjugates (ADC), which are now being utilized across all known molecular subtypes. ADCs represent a groundbreaki...

关键词： Antibody drug conjugate | Breast cancer | Safety | Toxicity | TRASTUZUMAB EMTANSINE | SACITUZUMAB GOVITECAN | OPEN-LABEL | DERUXTECAN | IMMUNOCONJUGATE | PHASE-1

摘要：In 2023, the improvement of our therapeutic management has largely taken shape. The aim of our article is to highlight the major advances that will change our practices. These are not only in the fiel...

关键词： New treatments in | oncology | Updates in 2023 | OPEN-LABEL | PLUS CHEMOTHERAPY | HODGKIN LYMPHOMA | PHASE-III | CANCER | PEMBROLIZUMAB | CARCINOMA...

摘要：Introduction > The French medical residency system requires the completion and subsequent defense of a thesis. Only a minority of this work is eventually published in an peer-reviewed journal. The mai...

关键词： Medical Oncology | Medical studies | Residency | Medical thesis | Publication

摘要：Background Current guidelines recommend adjuvant chemotherapy for patients with small, lymph node-negative, triple-negative breast cancer (TNBC) measuring >5 mm (T1b disease), but clinical evidence to...

关键词： adjuvant chemotherapy | lymph node-negative | meta-analysis | small | single-center study | triple-negative breast cancer

摘要：BackgroundTumour features associated with isolated invasive breast cancer (BC) ipsilateral local recurrence (ILR) after breast conservative treatment (BCT) and consequences on overall survival (OS) ar...

关键词： Ipsilateral | Local recurrence | Breast cancer | Survival | Prognosis

摘要：BackgroundInvasive lobular carcinomas (ILCs) represent approximately 10% of all breast cancers. Despite this high frequency, benefit of adjuvant chemotherapy (CT) is still unclear.MethodsOur objective...

关键词： Adjuvant chemotherapy | Breast cancer | Lobular | Hormone receptor-positive

摘要：Homeopathic medicines are used by many patients with cancer, usually alongside conventional treatment. A recent report by the European Academies' Science Advisory Council concluded that "that there ar...

关键词： Homeopathy | Cancer | Complementary and alternative medication | Treatments | Adverse events

摘要：Benefit of adjuvant trastuzumab-based chemotherapy for node-positive and/or > 1 cm human epidermal growth factor receptor 2-positive (HER2+) breast carcinomas has been clearly demonstrated in randomiz...

关键词： Subcentimetric breast cancer | HER2 | Adjuvant chemotherapy | Trastuzumab

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