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1. Management of serotonin syndrome (toxicity) NSTL国家科技图书文献中心

Chiew, Angela L. |  Isbister, Geoffrey K... -  《British Journal of Clinical Pharmacology》 - 2025,91(3) - 654~661 - 共8页

摘要:Serotonin syndrome (toxicity), resulting from an excessive accumulation of serotonin in the central nervous system, it can occur due to various factors such as the initiation of medication, overdose o...
关键词: cyproheptadine |  serotonin antagonist |  serotonin syndrome |  serotonin toxicity |  treatment

2. Early cardiovascular collapse after envenoming by snakes in Australia, 2005-2020: an observational study (ASP-31) NSTL国家科技图书文献中心

Isbister, Geoffrey K... |  Isoardi, Katherine Z...... -  《The Medical journal of Australia.》 - 2025,222(6) - 313~317 - 共5页

摘要:Objectives: To investigate the frequency, timing, and characteristics of cardiovascular collapse after snakebite in Australia, and the complications of collapse following envenoming. Study design: Obs...
关键词: Snake bites |  Hypotension |  Coagulation disorders

3. A prospective study of acute propranolol overdose defining dose thresholds of severe toxicity (ATOM-9) NSTL国家科技图书文献中心

Isoardi, Katherine Z... |  Chiew, Angela L.... -  《Clinical toxicology》 - 2025,63(1) - 1~9 - 共9页

摘要:Introduction Propranolol is a beta-adrenoceptor blocking drug with sodium channel-blocking properties that can cause life-threatening toxicity in overdose. Limited research defines dose thresholds of ...
关键词: Beta-adrenoceptor blocking drug |  bicarbonate |  overdose |  propranolol |  sodium channel blockade

4. Real world delays in antivenom administration: patient, snake or hospital factors (ASP-33) NSTL国家科技图书文献中心

Isbister, Geoffrey K... |  Chiew, Angela L.... -  《Clinical toxicology》 - 2025,63(1) - 10~15 - 共6页

摘要:ObjectiveEarly antivenom administration is essential for effective treatment. We investigated the delays in antivenom administration. MethodsWe reviewed snakebites from the Australian Snakebite Projec...
关键词: Delay to therapy |  diagnosis |  envenomation |  snakebite |  venom

5. Rivastigmine for the management of anticholinergic delirium NSTL国家科技图书文献中心

Chiew, Angela L. |  Holford, Amanda G.... -  《Clinical toxicology: the official journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists》 - 2024,62(2) - 82~87 - 共6页

摘要:IntroductionAnticholinergic agents are commonly taken in overdose, often causing delirium. The spectrum of anticholinergic delirium ranges from mild agitation to severe behavioural disturbance. Physos...
关键词: Anticholinergic |  antimuscarinic |  cholinesterase inhibitor |  rivastigmine |  antidote |  delirium |  ACETYLCHOLINESTERASE INHIBITION |  ALZHEIMERS-DISEASE |  TRANSDERMAL PATCH |  PHYSOSTIGMINE...

6. Cognitive impairment following sedative overdose NSTL国家科技图书文献中心

Stewart, Patrick T. |  Rahman, Md Bayzidur... -  《Clinical toxicology: the official journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists》 - 2024,62(3) - 152~163 - 共12页

摘要:Introduction: Patients with sedative overdose may have residual cognitive impairment at the time they are deemed medically cleared for discharge. Impairment could affect the performance of high-risk a...
关键词: Sedative |  central nervous system depressants |  poisoning |  drug overdose |  cognitive impairment |  trail-making test |  OLDER DRIVERS |  DRUG OVERDOSE |  TRAIL |  RISK

8. Advances in the understanding of acetaminophen toxicity mechanisms: a clinical toxicology perspective NSTL国家科技图书文献中心

Chiew, Angela L. |  Isbister, Geoffrey K... -  《Expert opinion on drug metabolism & toxicology》 - 2023,19(7/12) - 601~616 - 共16页 - 被引量:3

摘要:IntroductionAcetaminophen (paracetamol) is a commonly used analgesic and antipyretic agent, which is safe in therapeutic doses. Acetaminophen poisoning due to self-harm or repeated supratherapeutic in...
关键词: Hepatotoxicity |  poisoning |  biomarker |  acute liver injury |  paracetamol |  management |  AMINOTRANSFERASE MULTIPLICATION PRODUCT |  INTRAVENOUS N-ACETYLCYSTEINE |  MITOCHONDRIAL OXIDANT STRESS |  FULMINANT HEPATIC-FAILURE...

9. Acetaminophen Metabolites on Presentation Following an Acute Acetaminophen Overdose (ATOM-7) NSTL国家科技图书文献中心

Chiew, Angela L. L. |  Isbister, Geoffrey K...... -  《Clinical Pharmacology and Therapeutics》 - 2023,113(6) - 1304~1314 - 共11页 - 被引量:5

摘要:Acetaminophen (APAP) is commonly taken in overdose and can cause acute liver injury via the toxic metabolite NAPQI formed by cytochrome (CYP) P450 pathway. We aimed to evaluate the concentrations of A...
关键词: MASSIVE PARACETAMOL OVERDOSE |  RELEASE PARACETAMOL |  N-ACETYLCYSTEINE |  PROTEIN ADDUCTS |  SULFATION |  SULFOTRANSFERASES |  PHARMACOKINETICS |  MULTICENTER |  BIOMARKERS |  KINETICS

10. The serotonin toxidrome: shortfalls of current diagnostic criteria for related syndromes SCIE Web of Science核心 NSTL国家科技图书文献中心

Chiew, Angela L. |  Buckley, Nicholas A. -  《Clinical toxicology: the official journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists》 - 2022,60(2) - 143~158 - 共16页 - 被引量:17

摘要:Introduction Serotonin syndrome (toxicity) describes adverse drug effects from toxic amounts of intra-synaptic central nervous system serotonin. A wide range of drugs have been implicated to cause ser...
关键词: Serotonin syndrome |  serotonin toxicity |  diagnosis |  diagnostic criteria |  ANIMAL-MODEL |  REUPTAKE INHIBITORS |  COMBINATION RISPERIDONE |  TOXICITY |  HYPERTHERMIA |  MOCLOBEMIDE...
检索条件作者:Chiew, Angela L.

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