NSTL国家科技图书文献中心

1. Detection of sensory deficits in fine nerve fibres in leprosy diagnosis NSTL国家科技图书文献中心

Rodrigues Junior, Is... | Chaves, Ana Thereza ... - 《Tropical Medicine and International Health》 - 2025,30(3) - 170～180 - 共11页

摘要：ObjectivesThe purpose of this study was to determine reference points for thermal perception in cutaneous lesions of leprosy, a disease caused by Mycobacterium leprae characterised by hypoesthesia in ...

关键词： leprosy | Semmes-Weinstein monofilament | skin lesions | thermal sensory analyser | touch-pressure thresholds | warm and cold perception thresholds | Semmes‐Weinstein monofilament | touch‐pressure thresholds

2. Reduced vitamin D receptor (VDR) and cathelicidin antimicrobial peptide (CAMP) gene expression contribute to the maintenance of inflammatory immune response in leprosy patients NSTL国家科技图书文献中心

de Oliveira, Ana Lau... | Chaves, Ana Thereza ... - 《Microbes and infection》 - 2022,24(6/7) - 104981～104981 - 共7页 - 被引量：2

摘要：Leprosy is an infectious disease influenced by genetic, immunological, and environmental factors. Reduced gene expressions may be associated with the immunological response pattern and leprosy suscept...

关键词： Leprosy | Vitamin D receptor | Cathelicidin antimicrobial peptide | Gene expression | Path analysis | 1 | 25-DIHYDROXYVITAMIN D-3 | CUTTING EDGE | CELLS | ASSOCIATION...

3. Hypovitaminosis D and reduced cathelicidin are strongly correlated during the multidrug therapy against leprosy SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Grossi de Oliveira, ... | Chaves, Ana Thereza ... - 《Microbial Pathogenesis》 - 2020,147 - 共6页 - 被引量：1

摘要：Mycobacterium leprae infection depends on the competence of the host immune defense to induce effective protection against this intracellular pathogen. The present study investigated the serum levels ...

关键词： Leprosy | M. leprae | Vitamin D-3 | Cathelicidin | Leprosy drug therapy

4. The prognostic value of health-related quality of life in patients with Chagas heart disease SCIE Web of Science核心 SSCI 社会科学引文索引 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Costa, Henrique Silv... | Oliveira Lima, Marci...... - 《Quality of life research: An international journal of quality of life aspects of treatment, care and rehabilitation》 - 2019,28(1) - 67～72 - 共6页 - 被引量：12

摘要：PurposeTo verify the prognostic value of health-related quality of life (HRQoL) and the differences in HRQoL and clinical variables between groups of Chagas heart disease (CHD) patients with and witho...

关键词： Chagas disease | Chagas heart disease | Health-related quality of life | Prognosis

5. Immunogenomic screening approach to identify new antigens for the serological diagnosis of chronic Chagas' disease SCOPUS Scopus数据库 SCIE Web of Science核心 NSTL国家科技图书文献中心

Tonelli Elisei, Ruty... | Matos, Christiane Sa...... - 《Applied Microbiology and Biotechnology》 - 2018,102(14) - 6069～6080 - 共12页 - 被引量：13

摘要：Serological tests are preferentially used for the diagnosis of Chagas' disease (CD) during the chronic phase because of the low parasitemia and high anti-Trypanosoma cruzi antibody titers. However, th...

关键词： Trypanosoma cruzi | Chagas' disease | Immunoinformatics | B-cell epitope mapping | Immunodiagnosis | Peptides

6. Vitamin D receptor expression and hepcidin levels in the protection or severity of leprosy: a systematic review SCIE Web of Science核心 SCOPUS Scopus数据库 NSTL国家科技图书文献中心

Grossi de Oliveira, ... | Chaves, Ana Thereza ... - 《Microbes and infection》 - 2017,19(6) - 311～322 - 共12页 - 被引量：5

摘要：Leprosy is a chronic infectious disease whose disequilibrium in the host's genetic, immunological and clinical mechanisms leads to distinct manifestations defining the type of immunological response. ...

关键词： Leprosy | Vitamin D receptor | Polymorphism | Hepcidin | Protection | Severity

7. Recombinant proteins as promising antigens applied to the immunodiagnosis of Chagas disease: a scoping review

Resende, Carlos Anan... | Ribeiro, Anna Julia ... - 《Frontiers in Microbiology》 - 2024,15 - 共19页

摘要：Chagas disease (CD), caused by the protozoan Trypanosoma cruzi, is an important public health problem, occurring mainly in Latin America. The disease has a major social and economical effect, negative...

关键词： Chagas disease | Trypanosoma cruzi | diagnosis | recombinant | serodiagnosis | immunodiagnosis | LINKED-IMMUNOSORBENT-ASSAY | TRYPANOSOMA-CRUZI INFECTION | MULTIEPITOPE PROTEIN | DIAGNOSIS...

8. The use of peptides for immunodiagnosis of human Chagas disease

Ribeiro, Anna Julia | Silva, Kamila Alves ... - 《amino acids》 - 2024,56(1) - 共21页

摘要：Chagas disease, caused by the protozoa Trypanosoma cruzi, continues to be a serious public health problem in Latin America, worsened by the limitations in its detection. Given the importance of develo...

关键词： Chagas disease | Trypanosoma cruzi | Serodiagnosis | Imunodiagnosis; peptide | LINKED-IMMUNOSORBENT-ASSAY | TRYPANOSOMA-CRUZI | SYNTHETIC-PEPTIDE | ANTIGENIC EPITOPE | ANTIBODIES | ELISA...

9. Proof of Concept of a Novel Multiepitope Recombinant Protein for the Serodiagnosis of Patients with Chagas Disease

Machado, Juliana Mar... | Pereira, Isabela Amo...... - 《pathogens》 - 2023,12(2) - 共11页

摘要：Chagas disease remains a neglected disease that is considered to be a public health problem. The early diagnosis of cases is important to improve the prognosis of infected patients and prevent transmi...

关键词： multiepitope | recombinant protein | immunodiagnosis | Chagas disease | TRYPANOSOMA-CRUZI INFECTION | IN-HOUSE ELISA | DIAGNOSIS | MANAGEMENT | ANTIGENS | PEPTIDE

10. rMELEISH: A Novel Recombinant Multiepitope-Based Protein Applied to the Serodiagnosis of Both Canine and Human Visceral Leishmaniasis

Dias, Daniel Silva | Machado, Juliana Mar...... - 《pathogens》 - 2023,12(2) - 共13页

摘要：Background: visceral leishmaniasis (VL) is a critical public health problem in over ninety countries. The control measures adopted in Brazil have been insufficient when it comes to preventing the spre...

关键词： leishmaniasis | recombinant chimeric protein | serodiagnosis | visceral leishmaniasis | humans | dogs | HEAT-SHOCK PROTEINS | IMMUNE-RESPONSES | INFANTUM HSP70 | ENDEMIC AREA...